[{"map_name": "e_coli_core.Core metabolism", "map_id": "0df3827fde8464e80f455a773a52c274", "map_description": "E. coli core metabolic network\nLast Modified Fri Dec 05 2014 16:39:44 GMT-0800 (PST)", "homepage": "https://escher.github.io", "schema": "https://escher.github.io/escher/jsonschema/1-0-0#"}, {"reactions": {"1577514": {"name": "Formate transport in via proton symport", "bigg_id": "FORt2", "segments": {"11": {"to_node_id": "1577044", "from_node_id": "1576666", "b2": {"y": 4749.209372712298, "x": 1360.0}, "b1": {"y": 4827.353507999329, "x": 1360.0}}, "10": {"to_node_id": "1577046", "from_node_id": "1577045", "b2": null, "b1": null}, "13": {"to_node_id": "1576590", "from_node_id": "1577046", "b2": {"y": 4275.94781629675, "x": 1360.0}, "b1": {"y": 4411.784344889025, "x": 1360.0}}, "12": {"to_node_id": "1577044", "from_node_id": "1576833", "b2": {"y": 4744.773286702694, "x": 1360.0}, "b1": {"y": 4779.244289008981, "x": 1360.0}}, "14": {"to_node_id": "1576811", "from_node_id": "1577046", "b2": {"y": 4422.5658350974745, "x": 1360.0}, "b1": {"y": 4455.769750529243, "x": 1360.0}}, "9": {"to_node_id": "1577045", "from_node_id": "1577044", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b2492", "name": "focB"}, {"bigg_id": "b0904", "name": "focA"}], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "for_e"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": 1.0, "bigg_id": "for_c"}, {"coefficient": -1.0, "bigg_id": "h_e"}], "label_x": 1255.7530517578125, "label_y": 4574.13232421875, "gene_reaction_rule": "b0904 or b2492"}, "1577518": {"name": "Formate transport via diffusion", "bigg_id": "FORti", "segments": {"15": {"to_node_id": "1577047", "from_node_id": "1576590", "b2": {"y": 4263.5, "x": 1460.0}, "b1": {"y": 4145.55, "x": 1460.0}}, "16": {"to_node_id": "1576666", "from_node_id": "1577047", "b2": {"y": 4654.322265625, "x": 1460.0}, "b1": {"y": 4488.7, "x": 1460.0}}}, "genes": [{"bigg_id": "b2492", "name": "focB"}, {"bigg_id": "b0904", "name": "focA"}], "reversibility": false, "metabolites": [{"coefficient": 1.0, "bigg_id": "for_e"}, {"coefficient": -1.0, "bigg_id": "for_c"}], "label_x": 1479.5206298828125, "label_y": 4509.27197265625, "gene_reaction_rule": "b0904 or b2492"}, "1576747": {"name": "D-lactate dehydrogenase", "bigg_id": "LDH_D", "segments": {"120": {"to_node_id": "1576957", "from_node_id": "1576956", "b2": null, "b1": null}, "121": {"to_node_id": "1576955", "from_node_id": "1576957", "b2": null, "b1": null}, "122": {"to_node_id": "1576956", "from_node_id": "1576633", "b2": {"y": 4240.660459763366, "x": 1055.0}, "b1": {"y": 4277.201532544553, "x": 1055.0}}, "123": {"to_node_id": "1576956", "from_node_id": "1576584", "b2": {"y": 4243.0, "x": 1055.0}, "b1": {"y": 4285.0, "x": 1055.0}}, "124": {"to_node_id": "1576634", "from_node_id": "1576955", "b2": {"y": 4060.9687576256715, "x": 1055.0}, "b1": {"y": 4105.790627287702, "x": 1055.0}}, "125": {"to_node_id": "1576511", "from_node_id": "1576955", "b2": {"y": 4035.0, "x": 1055.0}, "b1": {"y": 4098.0, "x": 1055.0}}, "126": {"to_node_id": "1576635", "from_node_id": "1576955", "b2": {"y": 4072.7984674554473, "x": 1055.0}, "b1": {"y": 4109.339540236634, "x": 1055.0}}}, "genes": [{"bigg_id": "b1380", "name": "ldhA"}, {"bigg_id": "b2133", "name": "dld"}], "reversibility": true, "metabolites": [{"coefficient": 1.0, "bigg_id": "pyr_c"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": -1.0, "bigg_id": "lac__D_c"}, {"coefficient": -1.0, "bigg_id": "nad_c"}, {"coefficient": 1.0, "bigg_id": "nadh_c"}], "label_x": 1065.0, "label_y": 4165.0, "gene_reaction_rule": "b2133 or b1380"}, "1576746": {"name": "ATP maintenance requirement", "bigg_id": "ATPM", "segments": {"115": {"to_node_id": "1576952", "from_node_id": "1576534", "b2": {"y": 1176.0, "x": 4215.0}, "b1": {"y": 1120.0, "x": 4215.0}}, "114": {"to_node_id": "1576954", "from_node_id": "1576953", "b2": null, "b1": null}, "117": {"to_node_id": "1576631", "from_node_id": "1576954", "b2": {"y": 1411.0327780786686, "x": 4215.0}, "b1": {"y": 1368.3098334236006, "x": 4215.0}}, "116": {"to_node_id": "1576952", "from_node_id": "1576630", "b2": {"y": 1187.2720779386423, "x": 4215.0}, "b1": {"y": 1157.5735931288073, "x": 4215.0}}, "113": {"to_node_id": "1576953", "from_node_id": "1576952", "b2": null, "b1": null}, "119": {"to_node_id": "1576536", "from_node_id": "1576954", "b2": {"y": 1430.0, "x": 4215.0}, "b1": {"y": 1374.0, "x": 4215.0}}, "118": {"to_node_id": "1576632", "from_node_id": "1576954", "b2": {"y": 1388.0788655293195, "x": 4215.0}, "b1": {"y": 1361.423659658796, "x": 4215.0}}}, "genes": [], "reversibility": false, "metabolites": [{"coefficient": 1.0, "bigg_id": "adp_c"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": -1.0, "bigg_id": "atp_c"}, {"coefficient": -1.0, "bigg_id": "h2o_c"}, {"coefficient": 1.0, "bigg_id": "pi_c"}], "label_x": 4241.11474609375, "label_y": 1266.1151123046875, "gene_reaction_rule": ""}, "1576745": {"name": "Glutaminase", "bigg_id": "GLUN", "segments": {"108": {"to_node_id": "1576949", "from_node_id": "1576951", "b2": null, "b1": null}, "109": {"to_node_id": "1576950", "from_node_id": "1576628", "b2": {"y": 3888.700961498954, "x": 4247.0}, "b1": {"y": 3916.003204996513, "x": 4247.0}}, "111": {"to_node_id": "1576629", "from_node_id": "1576949", "b2": {"y": 3777.1681351239463, "x": 4247.0}, "b1": {"y": 3803.650440537184, "x": 4247.0}}, "110": {"to_node_id": "1576950", "from_node_id": "1576578", "b2": {"y": 3909.550345620285, "x": 4247.0}, "b1": {"y": 3985.501152067616, "x": 4247.0}}, "112": {"to_node_id": "1576554", "from_node_id": "1576949", "b2": {"y": 3723.4986338899794, "x": 4247.0}, "b1": {"y": 3787.5495901669938, "x": 4247.0}}, "107": {"to_node_id": "1576951", "from_node_id": "1576950", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b1524", "name": "glsB"}, {"bigg_id": "b0485", "name": "glsA"}, {"bigg_id": "b1812", "name": "pabB"}], "reversibility": false, "metabolites": [{"coefficient": 1.0, "bigg_id": "glu__L_c"}, {"coefficient": -1.0, "bigg_id": "gln__L_c"}, {"coefficient": 1.0, "bigg_id": "nh4_c"}, {"coefficient": -1.0, "bigg_id": "h2o_c"}], "label_x": 4253.77685546875, "label_y": 3866.338134765625, "gene_reaction_rule": "b1812 or b0485 or b1524"}, "1576744": {"name": "Acetate exchange", "bigg_id": "EX_ac_e", "segments": {"105": {"to_node_id": "1576947", "from_node_id": "1576627", "b2": {"y": 4890.0, "x": 1715.0}, "b1": {"y": 4888.64794921875, "x": 1715.0}}}, "genes": [], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "ac_e"}], "label_x": 1742.4544677734375, "label_y": 4917.06640625, "gene_reaction_rule": ""}, "1576743": {"name": "Glucose 6-phosphate dehydrogenase", "bigg_id": "G6PDH2r", "segments": {"99": {"to_node_id": "1576944", "from_node_id": "1576945", "b2": null, "b1": null}, "98": {"to_node_id": "1576945", "from_node_id": "1576946", "b2": null, "b1": null}, "102": {"to_node_id": "1576624", "from_node_id": "1576944", "b2": {"y": 1265.0, "x": 1393.0018939122203}, "b1": {"y": 1265.0, "x": 1346.800568173666}}, "103": {"to_node_id": "1576625", "from_node_id": "1576944", "b2": {"y": 1265.0, "x": 1381.6008241696038}, "b1": {"y": 1265.0, "x": 1343.3802472508812}}, "100": {"to_node_id": "1576946", "from_node_id": "1576623", "b2": {"y": 1265.0, "x": 1270.6197527491188}, "b1": {"y": 1265.0, "x": 1232.3991758303962}}, "101": {"to_node_id": "1576946", "from_node_id": "1576524", "b2": {"y": 1265.0, "x": 1252.2}, "b1": {"y": 1265.0, "x": 1171.0}}, "104": {"to_node_id": "1576626", "from_node_id": "1576944", "b2": {"y": 1265.0, "x": 1417.0}, "b1": {"y": 1265.0, "x": 1354.0}}}, "genes": [{"bigg_id": "b1852", "name": "zwf"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "g6p_c"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": -1.0, "bigg_id": "nadp_c"}, {"coefficient": 1.0, "bigg_id": "nadph_c"}, {"coefficient": 1.0, "bigg_id": "6pgl_c"}], "label_x": 1261.46337890625, "label_y": 1320.0572509765625, "gene_reaction_rule": "b1852"}, "1576742": {"name": "Malic enzyme (NAD)", "bigg_id": "ME1", "segments": {"91": {"to_node_id": "1576942", "from_node_id": "1576941", "b2": null, "b1": null}, "93": {"to_node_id": "1576941", "from_node_id": "1576504", "b2": {"y": 3307.175835174097, "x": 2355.6483296518063}, "b1": {"y": 3253.9194505803225, "x": 2462.161098839355}}, "92": {"to_node_id": "1576943", "from_node_id": "1576942", "b2": null, "b1": null}, "95": {"to_node_id": "1576511", "from_node_id": "1576943", "b2": {"y": 3870.856276574083, "x": 1117.2138384533964}, "b1": {"y": 3474.7533185191, "x": 2020.4933629618001}}, "94": {"to_node_id": "1576941", "from_node_id": "1576620", "b2": {"y": 3321.8944463483363, "x": 2326.2111073033275}, "b1": {"y": 3302.9814878277875, "x": 2364.0370243444254}}, "97": {"to_node_id": "1576622", "from_node_id": "1576943", "b2": {"y": 3415.0, "x": 2140.0}, "b1": {"y": 3397.5, "x": 2175.0}}, "96": {"to_node_id": "1576621", "from_node_id": "1576943", "b2": {"y": 3419.8328677803524, "x": 2130.3342644392947}, "b1": {"y": 3398.949860334106, "x": 2172.1002793317884}}}, "genes": [{"bigg_id": "b1479", "name": "maeA"}], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "mal__L_c"}, {"coefficient": 1.0, "bigg_id": "pyr_c"}, {"coefficient": 1.0, "bigg_id": "co2_c"}, {"coefficient": -1.0, "bigg_id": "nad_c"}, {"coefficient": 1.0, "bigg_id": "nadh_c"}], "label_x": 2188.595703125, "label_y": 3321.438232421875, "gene_reaction_rule": "b1479"}, "1576741": {"name": "GLNabc", "bigg_id": "GLNabc", "segments": {"88": {"to_node_id": "1576617", "from_node_id": "1576938", "b2": {"y": 4158.0, "x": 4332.993902665717}, "b1": {"y": 4158.0, "x": 4390.398170799715}}, "89": {"to_node_id": "1576618", "from_node_id": "1576938", "b2": {"y": 4158.0, "x": 4362.798467455447}, "b1": {"y": 4158.0, "x": 4399.339540236634}}, "90": {"to_node_id": "1576619", "from_node_id": "1576938", "b2": {"y": 4158.0, "x": 4350.968757625671}, "b1": {"y": 4158.0, "x": 4395.790627287702}}, "82": {"to_node_id": "1576939", "from_node_id": "1576940", "b2": null, "b1": null}, "83": {"to_node_id": "1576938", "from_node_id": "1576939", "b2": null, "b1": null}, "86": {"to_node_id": "1576940", "from_node_id": "1576616", "b2": {"y": 4158.0, "x": 4470.660459763366}, "b1": {"y": 4158.0, "x": 4507.201532544553}}, "87": {"to_node_id": "1576578", "from_node_id": "1576938", "b2": {"y": 4158.0, "x": 4324.643760591755}, "b1": {"y": 4158.0, "x": 4387.893128177527}}, "84": {"to_node_id": "1576940", "from_node_id": "1576537", "b2": {"y": 4158.0, "x": 4519.05}, "b1": {"y": 4158.0, "x": 4668.5}}, "85": {"to_node_id": "1576940", "from_node_id": "1576615", "b2": {"y": 4158.0, "x": 4474.209372712298}, "b1": {"y": 4158.0, "x": 4519.031242374329}}}, "genes": [{"bigg_id": "b0811", "name": "glnH"}, {"bigg_id": "b0810", "name": "glnP"}, {"bigg_id": "b0809", "name": "glnQ"}], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "h2o_c"}, {"coefficient": -1.0, "bigg_id": "atp_c"}, {"coefficient": -1.0, "bigg_id": "gln__L_e"}, {"coefficient": 1.0, "bigg_id": "adp_c"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": 1.0, "bigg_id": "pi_c"}, {"coefficient": 1.0, "bigg_id": "gln__L_c"}], "label_x": 4535.24462890625, "label_y": 4133.49658203125, "gene_reaction_rule": "b0811 and b0810 and b0809"}, "1577547": {"name": "Biomass Objective Function with GAM", "bigg_id": "BIOMASS_Ecoli_core_w_GAM", "segments": {"498": {"to_node_id": "1577090", "from_node_id": "1577076", "b2": {"y": 4899.2412109375, "x": 5215.0458984375}, "b1": {"y": 4793.48193359375, "x": 5334.0517578125}}, "499": {"to_node_id": "1577091", "from_node_id": "1577076", "b2": {"y": 4977.43115234375, "x": 5353.5947265625}, "b1": {"y": 4789.48193359375, "x": 5334.0517578125}}, "494": {"to_node_id": "1577086", "from_node_id": "1577074", "b2": {"y": 4564.25048828125, "x": 5140.27099609375}, "b1": {"y": 4681.48193359375, "x": 5334.0517578125}}, "495": {"to_node_id": "1577087", "from_node_id": "1577076", "b2": {"y": 4938.26416015625, "x": 5273.55517578125}, "b1": {"y": 4793.48193359375, "x": 5334.0517578125}}, "496": {"to_node_id": "1577088", "from_node_id": "1577074", "b2": {"y": 4579.03759765625, "x": 5068.69580078125}, "b1": {"y": 4681.48193359375, "x": 5334.0517578125}}, "497": {"to_node_id": "1577089", "from_node_id": "1577074", "b2": {"y": 4594.88134765625, "x": 5023.52734375}, "b1": {"y": 4681.48193359375, "x": 5334.0517578125}}, "490": {"to_node_id": "1577082", "from_node_id": "1577074", "b2": {"y": 4413.09912109375, "x": 5307.541015625}, "b1": {"y": 4681.48193359375, "x": 5334.0517578125}}, "491": {"to_node_id": "1577083", "from_node_id": "1577074", "b2": {"y": 4523.05615234375, "x": 5316.9716796875}, "b1": {"y": 4681.48193359375, "x": 5334.0517578125}}, "492": {"to_node_id": "1577084", "from_node_id": "1577074", "b2": {"y": 4533.61865234375, "x": 5258.0712890625}, "b1": {"y": 4681.48193359375, "x": 5334.0517578125}}, "493": {"to_node_id": "1577085", "from_node_id": "1577074", "b2": {"y": 4544.18115234375, "x": 5197.05859375}, "b1": {"y": 4681.48193359375, "x": 5334.0517578125}}, "506": {"to_node_id": "1577098", "from_node_id": "1577076", "b2": {"y": 4820.185546875, "x": 5099.533203125}, "b1": {"y": 4793.48193359375, "x": 5334.0517578125}}, "504": {"to_node_id": "1577096", "from_node_id": "1577076", "b2": {"y": 4868.333984375, "x": 5114.79541015625}, "b1": {"y": 4793.48193359375, "x": 5334.0517578125}}, "505": {"to_node_id": "1577097", "from_node_id": "1577074", "b2": {"y": 4717.4072265625, "x": 4780.78271484375}, "b1": {"y": 4681.48193359375, "x": 5334.0517578125}}, "502": {"to_node_id": "1577094", "from_node_id": "1577074", "b2": {"y": 4664.59423828125, "x": 4851.0517578125}, "b1": {"y": 4681.48193359375, "x": 5334.0517578125}}, "503": {"to_node_id": "1577095", "from_node_id": "1577074", "b2": {"y": 4685.7197265625, "x": 4807.9951171875}, "b1": {"y": 4681.48193359375, "x": 5334.0517578125}}, "500": {"to_node_id": "1577092", "from_node_id": "1577074", "b2": {"y": 4611.78173828125, "x": 4962.51416015625}, "b1": {"y": 4681.48193359375, "x": 5334.0517578125}}, "501": {"to_node_id": "1577093", "from_node_id": "1577074", "b2": {"y": 4637.1318359375, "x": 4907.83935546875}, "b1": {"y": 4681.48193359375, "x": 5334.0517578125}}, "489": {"to_node_id": "1577081", "from_node_id": "1577076", "b2": {"y": 5001.37158203125, "x": 5337.27587890625}, "b1": {"y": 4793.48193359375, "x": 5334.0517578125}}, "488": {"to_node_id": "1577080", "from_node_id": "1577074", "b2": {"y": 4453.01611328125, "x": 5350.98828125}, "b1": {"y": 4681.48193359375, "x": 5334.0517578125}}, "487": {"to_node_id": "1577079", "from_node_id": "1577074", "b2": {"y": 4516.16943359375, "x": 5423.4208984375}, "b1": {"y": 4681.48193359375, "x": 5334.0517578125}}, "486": {"to_node_id": "1577078", "from_node_id": "1577074", "b2": {"y": 4630.19921875, "x": 5427.28515625}, "b1": {"y": 4681.48193359375, "x": 5334.0517578125}}, "485": {"to_node_id": "1577077", "from_node_id": "1577076", "b2": {"y": 4926.6220703125, "x": 5391.197265625}, "b1": {"y": 4793.48193359375, "x": 5334.0517578125}}, "484": {"to_node_id": "1577073", "from_node_id": "1577074", "b2": {"y": 4573.30322265625, "x": 5455.328125}, "b1": {"y": 4685.48193359375, "x": 5334.0517578125}}, "483": {"to_node_id": "1577075", "from_node_id": "1577076", "b2": null, "b1": null}, "482": {"to_node_id": "1577075", "from_node_id": "1577074", "b2": null, "b1": null}}, "genes": [], "reversibility": false, "metabolites": [{"coefficient": 3.7478, "bigg_id": "coa_c"}, {"coefficient": -0.8977, "bigg_id": "r5p_c"}, {"coefficient": -1.496, "bigg_id": "3pg_c"}, {"coefficient": -0.361, "bigg_id": "e4p_c"}, {"coefficient": -0.2557, "bigg_id": "gln__L_c"}, {"coefficient": 3.547, "bigg_id": "nadh_c"}, {"coefficient": -2.8328, "bigg_id": "pyr_c"}, {"coefficient": -0.0709, "bigg_id": "f6p_c"}, {"coefficient": -13.0279, "bigg_id": "nadph_c"}, {"coefficient": -3.7478, "bigg_id": "accoa_c"}, {"coefficient": -1.7867, "bigg_id": "oaa_c"}, {"coefficient": -0.129, "bigg_id": "g3p_c"}, {"coefficient": -3.547, "bigg_id": "nad_c"}, {"coefficient": 59.81, "bigg_id": "pi_c"}, {"coefficient": -0.205, "bigg_id": "g6p_c"}, {"coefficient": 4.1182, "bigg_id": "akg_c"}, {"coefficient": -0.5191, "bigg_id": "pep_c"}, {"coefficient": -4.9414, "bigg_id": "glu__L_c"}, {"coefficient": -59.81, "bigg_id": "atp_c"}, {"coefficient": 59.81, "bigg_id": "adp_c"}, {"coefficient": 59.81, "bigg_id": "h_c"}, {"coefficient": -59.81, "bigg_id": "h2o_c"}, {"coefficient": 13.0279, "bigg_id": "nadp_c"}], "label_x": 5392.94580078125, "label_y": 4746.6962890625, "gene_reaction_rule": ""}, "1576749": {"name": "H2O transport via diffusion", "bigg_id": "H2Ot", "segments": {"135": {"to_node_id": "1576640", "from_node_id": "1576961", "b2": {"y": 4524.0, "x": 3257.0}, "b1": {"y": 4587.0, "x": 3257.0}}, "134": {"to_node_id": "1576961", "from_node_id": "1576639", "b2": {"y": 4684.0, "x": 3257.0}, "b1": {"y": 4733.0, "x": 3257.0}}}, "genes": [{"bigg_id": "s0001", "name": "None"}, {"bigg_id": "b0875", "name": "aqpZ"}], "reversibility": true, "metabolites": [{"coefficient": 1.0, "bigg_id": "h2o_c"}, {"coefficient": -1.0, "bigg_id": "h2o_e"}], "label_x": 3267.0, "label_y": 4604.0, "gene_reaction_rule": "b0875 or s0001"}, "1576748": {"name": "Malate dehydrogenase", "bigg_id": "MDH", "segments": {"133": {"to_node_id": "1576521", "from_node_id": "1576958", "b2": {"y": 3595.960728582294, "x": 2580.6915524727365}, "b1": {"y": 3497.9882185746883, "x": 2578.807465741821}}, "132": {"to_node_id": "1576638", "from_node_id": "1576958", "b2": {"y": 3505.0826757349405, "x": 2578.9438976102874}, "b1": {"y": 3470.7248027204823, "x": 2578.2831692830864}}, "131": {"to_node_id": "1576637", "from_node_id": "1576958", "b2": {"y": 3538.2116199944217, "x": 2579.5809926922}, "b1": {"y": 3480.6634859983265, "x": 2578.47429780766}}, "130": {"to_node_id": "1576960", "from_node_id": "1576636", "b2": {"y": 3327.0487806839114, "x": 2583.107239628261}, "b1": {"y": 3294.4959356130375, "x": 2585.69079876087}}, "127": {"to_node_id": "1576959", "from_node_id": "1576960", "b2": null, "b1": null}, "128": {"to_node_id": "1576958", "from_node_id": "1576959", "b2": null, "b1": null}, "129": {"to_node_id": "1576960", "from_node_id": "1576504", "b2": {"y": 3317.969496697346, "x": 2583.827817722433}, "b1": {"y": 3264.23165565782, "x": 2588.092725741443}}}, "genes": [{"bigg_id": "b3236", "name": "mdh"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "mal__L_c"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": 1.0, "bigg_id": "oaa_c"}, {"coefficient": -1.0, "bigg_id": "nad_c"}, {"coefficient": 1.0, "bigg_id": "nadh_c"}], "label_x": 2587.0, "label_y": 3394.0, "gene_reaction_rule": "b3236"}, "1577545": {"name": "Succinate dehydrogenase (irreversible)", "bigg_id": "SUCDi", "segments": {"48": {"to_node_id": "1577066", "from_node_id": "1577065", "b2": null, "b1": null}, "49": {"to_node_id": "1577064", "from_node_id": "1576814", "b2": {"y": 2816.4590794794085, "x": 3193.7934732750823}, "b1": {"y": 2815.1969315980286, "x": 3225.9782442502737}}, "47": {"to_node_id": "1577065", "from_node_id": "1577064", "b2": null, "b1": null}, "51": {"to_node_id": "1576503", "from_node_id": "1577066", "b2": {"y": 2843.2084583195547, "x": 2952.624089386102}, "b1": {"y": 2831.162537495866, "x": 3040.3872268158307}}, "50": {"to_node_id": "1577064", "from_node_id": "1576533", "b2": {"y": 2815.5590310361767, "x": 3216.7447085774984}, "b1": {"y": 2812.1967701205886, "x": 3302.482361924995}}, "52": {"to_node_id": "1576830", "from_node_id": "1577066", "b2": {"y": 2833.0526323200284, "x": 3026.6165359540787}, "b1": {"y": 2828.1157896960085, "x": 3062.5849607862237}}}, "genes": [{"bigg_id": "b0724", "name": "sdhB"}, {"bigg_id": "b0721", "name": "sdhC"}, {"bigg_id": "b0722", "name": "sdhD"}, {"bigg_id": "b0723", "name": "sdhA"}], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "succ_c"}, {"coefficient": 1.0, "bigg_id": "fum_c"}, {"coefficient": -1.0, "bigg_id": "q8_c"}, {"coefficient": 1.0, "bigg_id": "q8h2_c"}], "label_x": 3108.851318359375, "label_y": 2862.949951171875, "gene_reaction_rule": "b0721 and b0722 and b0723 and b0724"}, "1577540": {"name": "NADH dehydrogenase (ubiquinone-8 & 3 protons)", "bigg_id": "NADH16", "segments": {"39": {"to_node_id": "1577062", "from_node_id": "1577061", "b2": null, "b1": null}, "46": {"to_node_id": "1576542", "from_node_id": "1577063", "b2": {"y": 2507.151123046875, "x": 4630.938294107013}, "b1": {"y": 2571.611572265625, "x": 4800.053949169604}}, "44": {"to_node_id": "1576808", "from_node_id": "1577063", "b2": {"y": 2570.0, "x": 4780.0}, "b1": {"y": 2568.388427734375, "x": 4766.45361328125}}, "45": {"to_node_id": "1576809", "from_node_id": "1577063", "b2": {"y": 2655.409912109375, "x": 4928.099683314913}, "b1": {"y": 2570.000244140625, "x": 4798.6355690569735}}, "42": {"to_node_id": "1577061", "from_node_id": "1576827", "b2": {"y": 2570.0, "x": 4595.729021023612}, "b1": {"y": 2567.302001953125, "x": 4458.799047943291}}, "43": {"to_node_id": "1577061", "from_node_id": "1576539", "b2": {"y": 2570.0, "x": 4542.513923505967}, "b1": {"y": 2375.007080078125, "x": 4706.342147363639}}, "40": {"to_node_id": "1577063", "from_node_id": "1577062", "b2": null, "b1": null}, "41": {"to_node_id": "1577061", "from_node_id": "1576820", "b2": {"y": 2570.0, "x": 4582.0}, "b1": {"y": 2570.0, "x": 4470.0}}}, "genes": [{"bigg_id": "b2284", "name": "nuoF"}, {"bigg_id": "b2279", "name": "nuoK"}, {"bigg_id": "b2287", "name": "nuoB"}, {"bigg_id": "b2286", "name": "nuoC"}, {"bigg_id": "b2288", "name": "nuoA"}, {"bigg_id": "b2283", "name": "nuoG"}, {"bigg_id": "b2277", "name": "nuoM"}, {"bigg_id": "b2281", "name": "nuoI"}, {"bigg_id": "b2280", "name": "nuoJ"}, {"bigg_id": "b2276", "name": "nuoN"}, {"bigg_id": "b2282", "name": "nuoH"}, {"bigg_id": "b2278", "name": "nuoL"}, {"bigg_id": "b2285", "name": "nuoE"}], "reversibility": false, "metabolites": [{"coefficient": 3.0, "bigg_id": "h_e"}, {"coefficient": -1.0, "bigg_id": "q8_c"}, {"coefficient": -1.0, "bigg_id": "nadh_c"}, {"coefficient": 1.0, "bigg_id": "q8h2_c"}, {"coefficient": -4.0, "bigg_id": "h_c"}, {"coefficient": 1.0, "bigg_id": "nad_c"}], "label_x": 4589.75537109375, "label_y": 2624.46044921875, "gene_reaction_rule": "b2276 and b2277 and b2278 and b2279 and b2280 and b2281 and b2282 and b2283 and b2284 and b2285 and b2286 and b2287 and b2288"}, "1577507": {"name": "Alcohol dehydrogenase (ethanol)", "bigg_id": "ALCD2x", "segments": {"3": {"to_node_id": "1577043", "from_node_id": "1577042", "b2": null, "b1": null}, "2": {"to_node_id": "1577042", "from_node_id": "1577041", "b2": null, "b1": null}, "5": {"to_node_id": "1577041", "from_node_id": "1576822", "b2": {"y": 4111.911975251582, "x": 2383.7628306266947}, "b1": {"y": 4139.7065841719395, "x": 2413.5427687556494}}, "4": {"to_node_id": "1577041", "from_node_id": "1576829", "b2": {"y": 4118.6722220553565, "x": 2391.0059522021684}, "b1": {"y": 4162.240740184523, "x": 2437.6865073405606}}, "7": {"to_node_id": "1576813", "from_node_id": "1577043", "b2": {"y": 4033.046682944248, "x": 2306.576904081298}, "b1": {"y": 4059.6140048832744, "x": 2331.3730712243896}}, "6": {"to_node_id": "1576817", "from_node_id": "1577043", "b2": {"y": 4004.2974661013272, "x": 2279.744301694572}, "b1": {"y": 4050.989239830398, "x": 2323.3232905083714}}, "8": {"to_node_id": "1576824", "from_node_id": "1577043", "b2": {"y": 4021.1795086945217, "x": 2295.5008747815536}, "b1": {"y": 4056.0538526083565, "x": 2328.0502624344663}}}, "genes": [{"bigg_id": "b1241", "name": "adhE"}, {"bigg_id": "b0356", "name": "frmA"}, {"bigg_id": "b1478", "name": "adhP"}], "reversibility": true, "metabolites": [{"coefficient": 1.0, "bigg_id": "acald_c"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": -1.0, "bigg_id": "nad_c"}, {"coefficient": 1.0, "bigg_id": "nadh_c"}, {"coefficient": -1.0, "bigg_id": "etoh_c"}], "label_x": 2356.4794921875, "label_y": 4047.4384765625, "gene_reaction_rule": "b0356 or b1478 or b1241"}, "1576754": {"name": "Phosphoenolpyruvate synthase", "bigg_id": "PPS", "segments": {"151": {"to_node_id": "1576970", "from_node_id": "1576511", "b2": {"y": 3844.115214431216, "x": 835.0}, "b1": {"y": 3935.384048104053, "x": 835.0}}, "150": {"to_node_id": "1576970", "from_node_id": "1576642", "b2": {"y": 3821.7705098312485, "x": 835.0}, "b1": {"y": 3860.9016994374947, "x": 835.0}}, "153": {"to_node_id": "1576517", "from_node_id": "1576971", "b2": {"y": 3391.8647304430565, "x": 835.0}, "b1": {"y": 3485.059419132917, "x": 835.0}}, "152": {"to_node_id": "1576970", "from_node_id": "1576643", "b2": {"y": 3820.0, "x": 835.0}, "b1": {"y": 3855.0, "x": 835.0}}, "155": {"to_node_id": "1576645", "from_node_id": "1576971", "b2": {"y": 3475.0, "x": 835.0}, "b1": {"y": 3510.0, "x": 835.0}}, "154": {"to_node_id": "1576644", "from_node_id": "1576971", "b2": {"y": 3469.0983005625053, "x": 835.0}, "b1": {"y": 3508.2294901687515, "x": 835.0}}, "156": {"to_node_id": "1576646", "from_node_id": "1576971", "b2": {"y": 3454.289321881345, "x": 835.0}, "b1": {"y": 3503.7867965644036, "x": 835.0}}, "148": {"to_node_id": "1576972", "from_node_id": "1576970", "b2": null, "b1": null}, "149": {"to_node_id": "1576971", "from_node_id": "1576972", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b1702", "name": "ppsA"}], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "pyr_c"}, {"coefficient": -1.0, "bigg_id": "atp_c"}, {"coefficient": 1.0, "bigg_id": "amp_c"}, {"coefficient": 1.0, "bigg_id": "pep_c"}, {"coefficient": 2.0, "bigg_id": "h_c"}, {"coefficient": 1.0, "bigg_id": "pi_c"}, {"coefficient": -1.0, "bigg_id": "h2o_c"}], "label_x": 741.8604125976562, "label_y": 3669.90869140625, "gene_reaction_rule": "b1702"}, "1576755": {"name": "D-Glucose exchange", "bigg_id": "EX_glc__D_e", "segments": {"157": {"to_node_id": "1576974", "from_node_id": "1576647", "b2": {"y": 623.4132690429688, "x": 1056.6529541015625}, "b1": {"y": 625.4632568359375, "x": 1055.066162109375}}}, "genes": [], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "glc__D_e"}], "label_x": 1082.5206298828125, "label_y": 598.4705200195312, "gene_reaction_rule": ""}, "1576756": {"name": "ETOHt2r", "bigg_id": "ETOHt2r", "segments": {"159": {"to_node_id": "1576976", "from_node_id": "1576977", "b2": null, "b1": null}, "164": {"to_node_id": "1576829", "from_node_id": "1576975", "b2": {"y": 4328.998762383821, "x": 2500.0}, "b1": {"y": 4399.699628715146, "x": 2500.0}}, "160": {"to_node_id": "1576975", "from_node_id": "1576976", "b2": null, "b1": null}, "161": {"to_node_id": "1576977", "from_node_id": "1576648", "b2": {"y": 4745.660459763366, "x": 2500.0}, "b1": {"y": 4782.201532544553, "x": 2500.0}}, "162": {"to_node_id": "1576977", "from_node_id": "1576649", "b2": {"y": 4745.0, "x": 2500.0}, "b1": {"y": 4780.0, "x": 2500.0}}, "163": {"to_node_id": "1576650", "from_node_id": "1576975", "b2": {"y": 4377.798467455447, "x": 2500.0}, "b1": {"y": 4414.339540236634, "x": 2500.0}}}, "genes": [], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "h_e"}, {"coefficient": 1.0, "bigg_id": "etoh_c"}, {"coefficient": -1.0, "bigg_id": "etoh_e"}, {"coefficient": 1.0, "bigg_id": "h_c"}], "label_x": 2530.6279296875, "label_y": 4611.404296875, "gene_reaction_rule": ""}, "1576757": {"name": "Phosphoglycerate mutase", "bigg_id": "PGM", "segments": {"165": {"to_node_id": "1576978", "from_node_id": "1576522", "b2": {"y": 3060.0, "x": 1055.0}, "b1": {"y": 3105.5, "x": 1055.0}}, "166": {"to_node_id": "1576486", "from_node_id": "1576978", "b2": {"y": 2935.0, "x": 1055.0}, "b1": {"y": 2977.0, "x": 1055.0}}}, "genes": [{"bigg_id": "b3612", "name": "gpmM"}, {"bigg_id": "b4395", "name": "ytjC"}, {"bigg_id": "b0755", "name": "gpmA"}], "reversibility": true, "metabolites": [{"coefficient": 1.0, "bigg_id": "3pg_c"}, {"coefficient": -1.0, "bigg_id": "2pg_c"}], "label_x": 1065.0, "label_y": 2985.0, "gene_reaction_rule": "b3612 or b4395 or b0755"}, "1576750": {"name": "H2O exchange", "bigg_id": "EX_h2o_e", "segments": {"136": {"to_node_id": "1576962", "from_node_id": "1576639", "b2": {"y": 4839.0, "x": 3257.0}, "b1": {"y": 4779.5, "x": 3257.0}}}, "genes": [], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "h2o_e"}], "label_x": 3267.0, "label_y": 4914.0, "gene_reaction_rule": ""}, "1576751": {"name": "Transketolase", "bigg_id": "TKT1", "segments": {"142": {"to_node_id": "1576546", "from_node_id": "1576966", "b2": {"y": 1816.322080948729, "x": 2070.2734375}, "b1": {"y": 1823.819109636181, "x": 2173.413330078125}}, "143": {"to_node_id": "1576545", "from_node_id": "1576966", "b2": {"y": 1821.0824569252916, "x": 2297.1806640625}, "b1": {"y": 1822.232439714306, "x": 2175.0}}, "140": {"to_node_id": "1576964", "from_node_id": "1576605", "b2": {"y": 1605.9896167668144, "x": 2175.0}, "b1": {"y": 1557.80791851959, "x": 2171.826416015625}}, "141": {"to_node_id": "1576964", "from_node_id": "1576558", "b2": {"y": 1607.9527328943145, "x": 2175.0}, "b1": {"y": 1558.0047151164654, "x": 2171.82666015625}}, "139": {"to_node_id": "1576966", "from_node_id": "1576965", "b2": null, "b1": null}, "138": {"to_node_id": "1576965", "from_node_id": "1576964", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b2465", "name": "tktB"}, {"bigg_id": "b2935", "name": "tktA"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "xu5p__D_c"}, {"coefficient": -1.0, "bigg_id": "r5p_c"}, {"coefficient": 1.0, "bigg_id": "g3p_c"}, {"coefficient": 1.0, "bigg_id": "s7p_c"}], "label_x": 2185.0, "label_y": 1685.0, "gene_reaction_rule": "b2935 or b2465"}, "1576752": {"name": "CO2 transporter via diffusion", "bigg_id": "CO2t", "segments": {"144": {"to_node_id": "1576967", "from_node_id": "1576544", "b2": {"y": 4679.0, "x": 3621.0}, "b1": {"y": 4731.5, "x": 3621.0}}, "145": {"to_node_id": "1576641", "from_node_id": "1576967", "b2": {"y": 4519.0, "x": 3621.0}, "b1": {"y": 4578.5, "x": 3621.0}}}, "genes": [{"bigg_id": "s0001", "name": "None"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "co2_e"}, {"coefficient": 1.0, "bigg_id": "co2_c"}], "label_x": 3631.0, "label_y": 4594.0, "gene_reaction_rule": "s0001"}, "1576753": {"name": "2-Oxoglutarate exchange", "bigg_id": "EX_akg_e", "segments": {"146": {"to_node_id": "1576969", "from_node_id": "1576598", "b2": {"y": 3228.0, "x": 4977.0}, "b1": {"y": 3228.0, "x": 4938.5}}}, "genes": [], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "akg_e"}], "label_x": 5042.0, "label_y": 3218.0, "gene_reaction_rule": ""}, "1576758": {"name": "Ethanol exchange", "bigg_id": "EX_etoh_e", "segments": {"167": {"to_node_id": "1576980", "from_node_id": "1576649", "b2": {"y": 4887.93359375, "x": 2500.0}, "b1": {"y": 4875.1484375, "x": 2500.0}}}, "genes": [], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "etoh_e"}], "label_x": 2519.520751953125, "label_y": 4934.28076171875, "gene_reaction_rule": ""}, "1576759": {"name": "Acetate kinase", "bigg_id": "ACKr", "segments": {"169": {"to_node_id": "1576982", "from_node_id": "1576981", "b2": null, "b1": null}, "174": {"to_node_id": "1576613", "from_node_id": "1576983", "b2": {"y": 4215.0, "x": 1715.0}, "b1": {"y": 4243.0, "x": 1715.0}}, "173": {"to_node_id": "1576653", "from_node_id": "1576983", "b2": {"y": 4202.798467455447, "x": 1715.0}, "b1": {"y": 4239.339540236634, "x": 1715.0}}, "172": {"to_node_id": "1576981", "from_node_id": "1576652", "b2": {"y": 4317.0, "x": 1715.0}, "b1": {"y": 4345.0, "x": 1715.0}}, "171": {"to_node_id": "1576981", "from_node_id": "1576651", "b2": {"y": 4320.660459763366, "x": 1715.0}, "b1": {"y": 4357.201532544553, "x": 1715.0}}, "170": {"to_node_id": "1576983", "from_node_id": "1576982", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b2296", "name": "ackA"}, {"bigg_id": "b3115", "name": "tdcD"}, {"bigg_id": "b1849", "name": "purT"}], "reversibility": true, "metabolites": [{"coefficient": 1.0, "bigg_id": "adp_c"}, {"coefficient": -1.0, "bigg_id": "ac_c"}, {"coefficient": 1.0, "bigg_id": "actp_c"}, {"coefficient": -1.0, "bigg_id": "atp_c"}], "label_x": 1737.694091796875, "label_y": 4293.5615234375, "gene_reaction_rule": "b3115 or b2296 or b1849"}, "1576710": {"name": "CO2 exchange", "bigg_id": "EX_co2_e", "segments": {"367": {"to_node_id": "1576871", "from_node_id": "1576544", "b2": {"y": 4834.0, "x": 3621.0}, "b1": {"y": 4778.0, "x": 3621.0}}}, "genes": [], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "co2_e"}], "label_x": 3631.0, "label_y": 4904.0, "gene_reaction_rule": ""}, "1576760": {"name": "Ammonia exchange", "bigg_id": "EX_nh4_e", "segments": {"175": {"to_node_id": "1576985", "from_node_id": "1576526", "b2": {"y": 4837.5, "x": 3990.0}, "b1": {"y": 4781.15, "x": 3989.3}}}, "genes": [], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "nh4_e"}], "label_x": 4001.0, "label_y": 4908.0, "gene_reaction_rule": ""}, "1576763": {"name": "Fumarate transport via proton symport  2 H ", "bigg_id": "FUMt2_2", "segments": {"191": {"to_node_id": "1576659", "from_node_id": "1576992", "b2": {"y": 1032.2015325445527, "x": 2840.0}, "b1": {"y": 995.6604597633658, "x": 2840.0}}, "190": {"to_node_id": "1576991", "from_node_id": "1576658", "b2": {"y": 714.3395402366342, "x": 2840.0}, "b1": {"y": 677.7984674554473, "x": 2840.0}}, "192": {"to_node_id": "1576503", "from_node_id": "1576992", "b2": {"y": 1950.0011597931211, "x": 2840.0}, "b1": {"y": 1271.0003479379363, "x": 2840.0}}, "187": {"to_node_id": "1576993", "from_node_id": "1576991", "b2": null, "b1": null}, "188": {"to_node_id": "1576992", "from_node_id": "1576993", "b2": null, "b1": null}, "189": {"to_node_id": "1576991", "from_node_id": "1576657", "b2": {"y": 718.0, "x": 2840.0}, "b1": {"y": 690.0, "x": 2840.0}}}, "genes": [{"bigg_id": "b3528", "name": "dctA"}], "reversibility": false, "metabolites": [{"coefficient": 1.0, "bigg_id": "fum_c"}, {"coefficient": 2.0, "bigg_id": "h_c"}, {"coefficient": -1.0, "bigg_id": "fum_e"}, {"coefficient": -2.0, "bigg_id": "h_e"}], "label_x": 2851.586669921875, "label_y": 845.8676147460938, "gene_reaction_rule": "b3528"}, "1576762": {"name": "Phosphate exchange", "bigg_id": "EX_pi_e", "segments": {"185": {"to_node_id": "1576989", "from_node_id": "1576594", "b2": {"y": 4909.82177734375, "x": 2880.0}, "b1": {"y": 4896.2666015625, "x": 2879.999755859375}}}, "genes": [], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "pi_e"}], "label_x": 2902.694091796875, "label_y": 4926.21484375, "gene_reaction_rule": ""}, "1576765": {"name": "D-glucose transport via PEP:Pyr PTS", "bigg_id": "GLCpts", "segments": {"201": {"to_node_id": "1576998", "from_node_id": "1576662", "b2": {"y": 830.8607140720374, "x": 1056.2982974892807}, "b1": {"y": 817.6128620109578, "x": 962.100078544998}}, "200": {"to_node_id": "1576999", "from_node_id": "1576997", "b2": null, "b1": null}, "203": {"to_node_id": "1576663", "from_node_id": "1576999", "b2": {"y": 1091.99109457335, "x": 1162.89990234375}, "b1": {"y": 1155.6497636747395, "x": 1056.5867919921875}}, "202": {"to_node_id": "1576998", "from_node_id": "1576647", "b2": {"y": 852.0646158583277, "x": 1054.6540059434642}, "b1": {"y": 841.218336226978, "x": 1054.4691636917553}}, "199": {"to_node_id": "1576997", "from_node_id": "1576998", "b2": null, "b1": null}, "204": {"to_node_id": "1576524", "from_node_id": "1576999", "b2": {"y": 1159.3526000976562, "x": 1055.0}, "b1": {"y": 1156.4998046875, "x": 1056.5867919921875}}}, "genes": [{"bigg_id": "b1621", "name": "malX"}, {"bigg_id": "b2416", "name": "ptsI"}, {"bigg_id": "b1817", "name": "manX"}, {"bigg_id": "b1101", "name": "ptsG"}, {"bigg_id": "b1818", "name": "manY"}, {"bigg_id": "b1819", "name": "manZ"}, {"bigg_id": "b2415", "name": "ptsH"}, {"bigg_id": "b2417", "name": "crr"}], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "pep_c"}, {"coefficient": 1.0, "bigg_id": "pyr_c"}, {"coefficient": -1.0, "bigg_id": "glc__D_e"}, {"coefficient": 1.0, "bigg_id": "g6p_c"}], "label_x": 1074.520263671875, "label_y": 929.0499877929688, "gene_reaction_rule": "(b2417 and b1101 and b2415 and b2416) or (b1817 and b1818 and b1819 and b2415 and b2416) or (b2417 and b1621 and b2415 and b2416)"}, "1576764": {"name": "Acetate reversible transport via proton symport", "bigg_id": "ACt2r", "segments": {"198": {"to_node_id": "1576661", "from_node_id": "1576996", "b2": {"y": 4430.253057299197, "x": 1719.76025390625}, "b1": {"y": 4485.835145705384, "x": 1715.0}}, "195": {"to_node_id": "1576994", "from_node_id": "1576627", "b2": {"y": 4760.0, "x": 1715.0}, "b1": {"y": 4779.13232421875, "x": 1716.5867919921875}}, "194": {"to_node_id": "1576996", "from_node_id": "1576995", "b2": null, "b1": null}, "197": {"to_node_id": "1576652", "from_node_id": "1576996", "b2": {"y": 4450.38818359375, "x": 1715.0}, "b1": {"y": 4489.49560546875, "x": 1715.0}}, "196": {"to_node_id": "1576994", "from_node_id": "1576660", "b2": {"y": 4760.660459763366, "x": 1715.0}, "b1": {"y": 4787.680536450803, "x": 1715.0}}, "193": {"to_node_id": "1576995", "from_node_id": "1576994", "b2": null, "b1": null}}, "genes": [], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "h_e"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": -1.0, "bigg_id": "ac_e"}, {"coefficient": 1.0, "bigg_id": "ac_c"}], "label_x": 1740.8675537109375, "label_y": 4638.470703125, "gene_reaction_rule": ""}, "1576766": {"name": "Succinate transport out via proton antiport", "bigg_id": "SUCCt3", "segments": {"205": {"to_node_id": "1577000", "from_node_id": "1577002", "b2": null, "b1": null}, "207": {"to_node_id": "1577002", "from_node_id": "1576664", "b2": {"y": 2844.388427734375, "x": 4392.512762612581}, "b1": {"y": 2928.186767578125, "x": 4395.992900114855}}, "210": {"to_node_id": "1576665", "from_node_id": "1577001", "b2": {"y": 2757.366943359375, "x": 4896.373608481642}, "b1": {"y": 2844.388427734375, "x": 4895.4172094976175}}, "206": {"to_node_id": "1577001", "from_node_id": "1577000", "b2": null, "b1": null}, "209": {"to_node_id": "1576531", "from_node_id": "1577001", "b2": {"y": 2846.0, "x": 4852.764726786234}, "b1": {"y": 2844.388427734375, "x": 4830.28303131712}}, "208": {"to_node_id": "1577002", "from_node_id": "1576533", "b2": {"y": 2846.0, "x": 4388.970989302984}, "b1": {"y": 2846.0, "x": 3989.9032976766134}}}, "genes": [], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "succ_c"}, {"coefficient": 1.0, "bigg_id": "succ_e"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": -1.0, "bigg_id": "h_e"}], "label_x": 4451.38818359375, "label_y": 2819.884765625, "gene_reaction_rule": ""}, "1576769": {"name": "Glyceraldehyde-3-phosphate dehydrogenase", "bigg_id": "GAPD", "segments": {"217": {"to_node_id": "1577008", "from_node_id": "1577006", "b2": null, "b1": null}, "218": {"to_node_id": "1577007", "from_node_id": "1577008", "b2": null, "b1": null}, "219": {"to_node_id": "1577006", "from_node_id": "1576575", "b2": {"y": 2322.5, "x": 1055.0}, "b1": {"y": 2270.0, "x": 1055.0}}, "224": {"to_node_id": "1576672", "from_node_id": "1577007", "b2": {"y": 2482.4341649025255, "x": 1055.0}, "b1": {"y": 2449.230249470758, "x": 1055.0}}, "223": {"to_node_id": "1576671", "from_node_id": "1577007", "b2": {"y": 2495.2079728939616, "x": 1055.0}, "b1": {"y": 2453.0623918681886, "x": 1055.0}}, "222": {"to_node_id": "1576487", "from_node_id": "1577007", "b2": {"y": 2500.0, "x": 1055.0}, "b1": {"y": 2454.5, "x": 1055.0}}, "221": {"to_node_id": "1577006", "from_node_id": "1576670", "b2": {"y": 2330.769750529242, "x": 1055.0}, "b1": {"y": 2297.5658350974745, "x": 1055.0}}, "220": {"to_node_id": "1577006", "from_node_id": "1576669", "b2": {"y": 2326.9376081318114, "x": 1055.0}, "b1": {"y": 2284.7920271060384, "x": 1055.0}}}, "genes": [{"bigg_id": "b1779", "name": "gapA"}], "reversibility": true, "metabolites": [{"coefficient": 1.0, "bigg_id": "13dpg_c"}, {"coefficient": -1.0, "bigg_id": "g3p_c"}, {"coefficient": 1.0, "bigg_id": "nadh_c"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": -1.0, "bigg_id": "nad_c"}, {"coefficient": -1.0, "bigg_id": "pi_c"}], "label_x": 1065.0, "label_y": 2385.0, "gene_reaction_rule": "b1779"}, "1576768": {"name": "6-phosphogluconolactonase", "bigg_id": "PGL", "segments": {"216": {"to_node_id": "1576490", "from_node_id": "1577004", "b2": {"y": 1265.0, "x": 1742.0}, "b1": {"y": 1265.0, "x": 1682.5}}, "214": {"to_node_id": "1577005", "from_node_id": "1576667", "b2": {"y": 1265.0, "x": 1600.6197527491188}, "b1": {"y": 1265.0, "x": 1562.3991758303962}}, "215": {"to_node_id": "1576668", "from_node_id": "1577004", "b2": {"y": 1265.0, "x": 1711.6008241696038}, "b1": {"y": 1265.0, "x": 1673.3802472508812}}, "212": {"to_node_id": "1577004", "from_node_id": "1577003", "b2": null, "b1": null}, "213": {"to_node_id": "1577005", "from_node_id": "1576626", "b2": {"y": 1265.0, "x": 1600.5}, "b1": {"y": 1265.0, "x": 1562.0}}, "211": {"to_node_id": "1577003", "from_node_id": "1577005", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b0767", "name": "pgl"}], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "6pgl_c"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": -1.0, "bigg_id": "h2o_c"}, {"coefficient": 1.0, "bigg_id": "6pgc_c"}], "label_x": 1599.3970947265625, "label_y": 1312.1234130859375, "gene_reaction_rule": "b0767"}, "1576699": {"name": "Pyruvate dehydrogenase", "bigg_id": "PDH", "segments": {"331": {"to_node_id": "1576514", "from_node_id": "1576851", "b2": {"y": 3945.0, "x": 1635.0}, "b1": {"y": 3945.0, "x": 1579.0}}, "330": {"to_node_id": "1576513", "from_node_id": "1576851", "b2": {"y": 3945.0, "x": 1606.478150704935}, "b1": {"y": 3945.0, "x": 1570.4434452114806}}, "332": {"to_node_id": "1576515", "from_node_id": "1576851", "b2": {"y": 3945.0, "x": 1613.309518948453}, "b1": {"y": 3945.0, "x": 1572.492855684536}}, "326": {"to_node_id": "1576851", "from_node_id": "1576850", "b2": null, "b1": null}, "327": {"to_node_id": "1576849", "from_node_id": "1576510", "b2": {"y": 3945.0, "x": 1413.3472975166192}, "b1": {"y": 3945.0, "x": 1374.4909917220637}}, "325": {"to_node_id": "1576850", "from_node_id": "1576849", "b2": null, "b1": null}, "328": {"to_node_id": "1576849", "from_node_id": "1576511", "b2": {"y": 3945.0, "x": 1373.75}, "b1": {"y": 3945.0, "x": 1242.5}}, "329": {"to_node_id": "1576849", "from_node_id": "1576512", "b2": {"y": 3945.0, "x": 1411.736306507171}, "b1": {"y": 3945.0, "x": 1369.1210216905704}}}, "genes": [{"bigg_id": "b0114", "name": "aceE"}, {"bigg_id": "b0115", "name": "aceF"}, {"bigg_id": "b0116", "name": "lpd"}], "reversibility": false, "metabolites": [{"coefficient": 1.0, "bigg_id": "nadh_c"}, {"coefficient": -1.0, "bigg_id": "coa_c"}, {"coefficient": -1.0, "bigg_id": "pyr_c"}, {"coefficient": 1.0, "bigg_id": "accoa_c"}, {"coefficient": -1.0, "bigg_id": "nad_c"}, {"coefficient": 1.0, "bigg_id": "co2_c"}], "label_x": 1417.72802734375, "label_y": 3920.71923828125, "gene_reaction_rule": "b0114 and b0115 and b0116"}, "1576698": {"name": "Isocitrate dehydrogenase (NADP)", "bigg_id": "ICDHyr", "segments": {"319": {"to_node_id": "1576848", "from_node_id": "1576846", "b2": null, "b1": null}, "318": {"to_node_id": "1576846", "from_node_id": "1576847", "b2": null, "b1": null}, "322": {"to_node_id": "1576507", "from_node_id": "1576848", "b2": {"y": 3735.4876397766343, "x": 3702.9108389651055}, "b1": {"y": 3767.3462919329904, "x": 3674.9732516895315}}, "323": {"to_node_id": "1576508", "from_node_id": "1576848", "b2": {"y": 3749.7955576929353, "x": 3690.36389556158}, "b1": {"y": 3771.6386673078805, "x": 3671.209168668474}}, "320": {"to_node_id": "1576847", "from_node_id": "1576505", "b2": {"y": 3933.673891941737, "x": 3498.9695345126847}, "b1": {"y": 3958.5796398057905, "x": 3468.565115042282}}, "321": {"to_node_id": "1576847", "from_node_id": "1576506", "b2": {"y": 3936.593890513596, "x": 3495.4048609314546}, "b1": {"y": 3968.312968378653, "x": 3456.6828697715146}}, "324": {"to_node_id": "1576509", "from_node_id": "1576848", "b2": {"y": 3715.2337610392046, "x": 3720.671932627159}, "b1": {"y": 3761.2701283117613, "x": 3680.3015797881476}}}, "genes": [{"bigg_id": "b1136", "name": "icd"}], "reversibility": true, "metabolites": [{"coefficient": 1.0, "bigg_id": "nadph_c"}, {"coefficient": 1.0, "bigg_id": "akg_c"}, {"coefficient": 1.0, "bigg_id": "co2_c"}, {"coefficient": -1.0, "bigg_id": "nadp_c"}, {"coefficient": -1.0, "bigg_id": "icit_c"}], "label_x": 3616.0, "label_y": 3836.0, "gene_reaction_rule": "b1136"}, "1576695": {"name": "O2 transport  diffusion ", "bigg_id": "O2t", "segments": {"304": {"to_node_id": "1576840", "from_node_id": "1576494", "b2": {"y": 1660.0, "x": 4755.0}, "b1": {"y": 1660.0, "x": 4821.5}}, "305": {"to_node_id": "1576495", "from_node_id": "1576840", "b2": {"y": 1660.0, "x": 4495.0}, "b1": {"y": 1660.0, "x": 4610.5}}}, "genes": [{"bigg_id": "s0001", "name": "None"}], "reversibility": true, "metabolites": [{"coefficient": 1.0, "bigg_id": "o2_c"}, {"coefficient": -1.0, "bigg_id": "o2_e"}], "label_x": 4557.1943359375, "label_y": 1635.4964599609375, "gene_reaction_rule": "s0001"}, "1576694": {"name": "Phosphogluconate dehydrogenase", "bigg_id": "GND", "segments": {"300": {"to_node_id": "1576838", "from_node_id": "1576490", "b2": {"y": 1265.0, "x": 1920.5}, "b1": {"y": 1265.0, "x": 1882.0}}, "301": {"to_node_id": "1576491", "from_node_id": "1576839", "b2": {"y": 1265.0, "x": 2029.2015325445527}, "b1": {"y": 1265.0, "x": 1992.660459763366}}, "302": {"to_node_id": "1576492", "from_node_id": "1576839", "b2": {"y": 1265.0, "x": 2041.0312423743285}, "b1": {"y": 1265.0, "x": 1996.2093727122985}}, "303": {"to_node_id": "1576493", "from_node_id": "1576839", "b2": {"y": 1265.0, "x": 2066.0}, "b1": {"y": 1265.0, "x": 2003.7}}, "298": {"to_node_id": "1576839", "from_node_id": "1576837", "b2": null, "b1": null}, "299": {"to_node_id": "1576838", "from_node_id": "1576489", "b2": {"y": 1265.0, "x": 1921.339540236634}, "b1": {"y": 1265.0, "x": 1884.7984674554473}}, "297": {"to_node_id": "1576837", "from_node_id": "1576838", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b2029", "name": "gnd"}], "reversibility": false, "metabolites": [{"coefficient": 1.0, "bigg_id": "ru5p__D_c"}, {"coefficient": 1.0, "bigg_id": "nadph_c"}, {"coefficient": 1.0, "bigg_id": "co2_c"}, {"coefficient": -1.0, "bigg_id": "nadp_c"}, {"coefficient": -1.0, "bigg_id": "6pgc_c"}], "label_x": 1930.5045166015625, "label_y": 1313.710205078125, "gene_reaction_rule": "b2029"}, "1576697": {"name": "Fumarase", "bigg_id": "FUM", "segments": {"317": {"to_node_id": "1576844", "from_node_id": "1576503", "b2": {"y": 3003.8745504813855, "x": 2741.433228320378}, "b1": {"y": 2961.5818349379524, "x": 2775.110761067927}}, "316": {"to_node_id": "1576844", "from_node_id": "1576502", "b2": {"y": 3010.0650991921693, "x": 2736.5037173099395}, "b1": {"y": 2982.216997307231, "x": 2758.679057699798}}, "315": {"to_node_id": "1576504", "from_node_id": "1576845", "b2": {"y": 3134.0, "x": 2652.5}, "b1": {"y": 3093.4, "x": 2674.55}}, "314": {"to_node_id": "1576845", "from_node_id": "1576844", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b4122", "name": "fumB"}, {"bigg_id": "b1611", "name": "fumC"}, {"bigg_id": "b1612", "name": "fumA"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "fum_c"}, {"coefficient": -1.0, "bigg_id": "h2o_c"}, {"coefficient": 1.0, "bigg_id": "mal__L_c"}], "label_x": 2759.057373046875, "label_y": 3066.0, "gene_reaction_rule": "b1612 or b4122 or b1611"}, "1576696": {"name": "NAD P  transhydrogenase", "bigg_id": "THD2", "segments": {"308": {"to_node_id": "1576842", "from_node_id": "1576496", "b2": {"y": 724.5066228070302, "x": 3510.0}, "b1": {"y": 580.5856339661426, "x": 3331.1220703125}}, "309": {"to_node_id": "1576842", "from_node_id": "1576497", "b2": {"y": 750.137689584216, "x": 3510.0}, "b1": {"y": 654.7419446101471, "x": 3418.143798828125}}, "313": {"to_node_id": "1576501", "from_node_id": "1576843", "b2": {"y": 1081.817596989458, "x": 3624.41748046875}, "b1": {"y": 1038.7769502394156, "x": 3506.777099609375}}, "312": {"to_node_id": "1576500", "from_node_id": "1576843", "b2": {"y": 1078.144282674624, "x": 3740.4462890625}, "b1": {"y": 1061.6865465211372, "x": 3508.388671875}}, "311": {"to_node_id": "1576499", "from_node_id": "1576843", "b2": {"y": 995.287841796875, "x": 3510.0}, "b1": {"y": 921.2841796875, "x": 3510.0}}, "310": {"to_node_id": "1576842", "from_node_id": "1576498", "b2": {"y": 777.5, "x": 3510.0}, "b1": {"y": 725.0, "x": 3510.0}}, "306": {"to_node_id": "1576841", "from_node_id": "1576842", "b2": null, "b1": null}, "307": {"to_node_id": "1576843", "from_node_id": "1576841", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b1602", "name": "pntB"}, {"bigg_id": "b1603", "name": "pntA"}], "reversibility": false, "metabolites": [{"coefficient": -2.0, "bigg_id": "h_e"}, {"coefficient": -1.0, "bigg_id": "nadp_c"}, {"coefficient": -1.0, "bigg_id": "nadh_c"}, {"coefficient": 1.0, "bigg_id": "nadph_c"}, {"coefficient": 2.0, "bigg_id": "h_c"}, {"coefficient": 1.0, "bigg_id": "nad_c"}], "label_x": 3532.891845703125, "label_y": 872.8489990234375, "gene_reaction_rule": "b1602 and b1603"}, "1576693": {"name": "Phosphoglycerate kinase", "bigg_id": "PGK", "segments": {"296": {"to_node_id": "1576488", "from_node_id": "1576834", "b2": {"y": 2617.5658350974745, "x": 1055.0}, "b1": {"y": 2650.769750529242, "x": 1055.0}}, "294": {"to_node_id": "1576835", "from_node_id": "1576486", "b2": {"y": 2790.0, "x": 1055.0}, "b1": {"y": 2825.0, "x": 1055.0}}, "295": {"to_node_id": "1576487", "from_node_id": "1576834", "b2": {"y": 2615.0, "x": 1055.0}, "b1": {"y": 2650.0, "x": 1055.0}}, "292": {"to_node_id": "1576834", "from_node_id": "1576836", "b2": null, "b1": null}, "293": {"to_node_id": "1576835", "from_node_id": "1576485", "b2": {"y": 2789.230249470758, "x": 1055.0}, "b1": {"y": 2822.4341649025255, "x": 1055.0}}, "291": {"to_node_id": "1576836", "from_node_id": "1576835", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b2926", "name": "pgk"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "3pg_c"}, {"coefficient": 1.0, "bigg_id": "13dpg_c"}, {"coefficient": -1.0, "bigg_id": "atp_c"}, {"coefficient": 1.0, "bigg_id": "adp_c"}], "label_x": 1065.0, "label_y": 2715.0, "gene_reaction_rule": "b2926"}, "1576776": {"name": "Malic enzyme (NADP)", "bigg_id": "ME2", "segments": {"270": {"to_node_id": "1576692", "from_node_id": "1577027", "b2": {"y": 3439.4108823397055, "x": 2161.178235320589}, "b1": {"y": 3418.8232647019117, "x": 2202.3534705961765}}, "267": {"to_node_id": "1577028", "from_node_id": "1576504", "b2": {"y": 3332.720745600581, "x": 2355.4654239990323}, "b1": {"y": 3269.069152001936, "x": 2461.551413330107}}, "266": {"to_node_id": "1577028", "from_node_id": "1576690", "b2": {"y": 3350.7069760509485, "x": 2325.4883732484195}, "b1": {"y": 3329.0232535031614, "x": 2361.6279108280646}}, "265": {"to_node_id": "1577027", "from_node_id": "1577026", "b2": null, "b1": null}, "264": {"to_node_id": "1577026", "from_node_id": "1577028", "b2": null, "b1": null}, "269": {"to_node_id": "1576511", "from_node_id": "1577027", "b2": {"y": 3895.002675936253, "x": 1164.309223322806}, "b1": {"y": 3495.997238327751, "x": 2048.005523344498}}, "268": {"to_node_id": "1576691", "from_node_id": "1577027", "b2": {"y": 3434.0831891575845, "x": 2171.8336216848306}, "b1": {"y": 3417.2249567472754, "x": 2205.550086505449}}}, "genes": [{"bigg_id": "b2463", "name": "maeB"}], "reversibility": false, "metabolites": [{"coefficient": 1.0, "bigg_id": "pyr_c"}, {"coefficient": -1.0, "bigg_id": "mal__L_c"}, {"coefficient": 1.0, "bigg_id": "co2_c"}, {"coefficient": -1.0, "bigg_id": "nadp_c"}, {"coefficient": 1.0, "bigg_id": "nadph_c"}], "label_x": 2281.107177734375, "label_y": 3432.36328125, "gene_reaction_rule": "b2463"}, "1576777": {"name": "Formate exchange", "bigg_id": "EX_for_e", "segments": {"271": {"to_node_id": "1577030", "from_node_id": "1576666", "b2": {"y": 4884.95458984375, "x": 1460.0}, "b1": {"y": 4885.96044921875, "x": 1461.5867919921875}}}, "genes": [], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "for_e"}], "label_x": 1476.3470458984375, "label_y": 4913.4130859375, "gene_reaction_rule": ""}, "1576774": {"name": "Citrate synthase", "bigg_id": "CS", "segments": {"252": {"to_node_id": "1577020", "from_node_id": "1576514", "b2": {"y": 3745.4027250468985, "x": 2627.479742988546}, "b1": {"y": 3679.773731927161, "x": 1727.7705707040077}}, "253": {"to_node_id": "1577020", "from_node_id": "1576684", "b2": {"y": 3823.2954829227556, "x": 2728.8970628128327}, "b1": {"y": 3791.3182764091857, "x": 2693.656876042776}}, "250": {"to_node_id": "1577022", "from_node_id": "1577020", "b2": null, "b1": null}, "251": {"to_node_id": "1577021", "from_node_id": "1577022", "b2": null, "b1": null}, "256": {"to_node_id": "1576686", "from_node_id": "1577021", "b2": {"y": 3971.425553937104, "x": 2910.1210395424487}, "b1": {"y": 3934.0276661811313, "x": 2861.0363118627347}}, "257": {"to_node_id": "1576687", "from_node_id": "1577021", "b2": {"y": 3980.7262047116856, "x": 2922.328143684087}, "b1": {"y": 3936.817861413506, "x": 2864.698443105226}}, "254": {"to_node_id": "1577020", "from_node_id": "1576521", "b2": {"y": 3822.7470798256522, "x": 2728.292700216025}, "b1": {"y": 3789.4902660855073, "x": 2691.642334053416}}, "255": {"to_node_id": "1576685", "from_node_id": "1577021", "b2": {"y": 3962.7252091426644, "x": 2898.7018369997472}, "b1": {"y": 3931.4175627427994, "x": 2857.610551099924}}}, "genes": [{"bigg_id": "b0720", "name": "gltA"}], "reversibility": false, "metabolites": [{"coefficient": 1.0, "bigg_id": "coa_c"}, {"coefficient": -1.0, "bigg_id": "oaa_c"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": 1.0, "bigg_id": "cit_c"}, {"coefficient": -1.0, "bigg_id": "accoa_c"}, {"coefficient": -1.0, "bigg_id": "h2o_c"}], "label_x": 2808.0, "label_y": 3876.0, "gene_reaction_rule": "b0720"}, "1576775": {"name": "Pyruvate transport in via proton symport", "bigg_id": "PYRt2", "segments": {"260": {"to_node_id": "1577023", "from_node_id": "1576688", "b2": {"y": 3945.0, "x": 359.3395402366342}, "b1": {"y": 3945.0, "x": 322.7984674554473}}, "261": {"to_node_id": "1577023", "from_node_id": "1576557", "b2": {"y": 3945.0, "x": 360.0}, "b1": {"y": 3945.0, "x": 325.0}}, "263": {"to_node_id": "1576689", "from_node_id": "1577024", "b2": {"y": 3945.0, "x": 697.2015325445527}, "b1": {"y": 3945.0, "x": 660.6604597633658}}, "262": {"to_node_id": "1576511", "from_node_id": "1577024", "b2": {"y": 3945.0, "x": 850.0}, "b1": {"y": 3945.0, "x": 706.5}}, "258": {"to_node_id": "1577025", "from_node_id": "1577023", "b2": null, "b1": null}, "259": {"to_node_id": "1577024", "from_node_id": "1577025", "b2": null, "b1": null}}, "genes": [], "reversibility": true, "metabolites": [{"coefficient": 1.0, "bigg_id": "pyr_c"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": -1.0, "bigg_id": "pyr_e"}, {"coefficient": -1.0, "bigg_id": "h_e"}], "label_x": 462.6368408203125, "label_y": 3908.02490234375, "gene_reaction_rule": ""}, "1576772": {"name": "Glutamate dehydrogenase (NADP)", "bigg_id": "GLUDy", "segments": {"238": {"to_node_id": "1576677", "from_node_id": "1577014", "b2": {"y": 3632.0, "x": 4021.2725815852687}, "b1": {"y": 3632.0, "x": 4060.9817744755806}}, "240": {"to_node_id": "1576509", "from_node_id": "1577014", "b2": {"y": 3632.0, "x": 3911.98117576612}, "b1": {"y": 3632.0, "x": 4028.194352729836}}, "241": {"to_node_id": "1576679", "from_node_id": "1577014", "b2": {"y": 3632.0, "x": 4036.853918777118}, "b1": {"y": 3632.0, "x": 4065.6561756331353}}, "239": {"to_node_id": "1576678", "from_node_id": "1577014", "b2": {"y": 3632.0, "x": 4000.5855310681522}, "b1": {"y": 3632.0, "x": 4054.775659320446}}, "234": {"to_node_id": "1577014", "from_node_id": "1577015", "b2": null, "b1": null}, "235": {"to_node_id": "1577016", "from_node_id": "1576675", "b2": {"y": 3632.0, "x": 4133.6977705423415}, "b1": {"y": 3632.0, "x": 4170.325901807804}}, "236": {"to_node_id": "1577016", "from_node_id": "1576554", "b2": {"y": 3632.0, "x": 4137.5}, "b1": {"y": 3632.0, "x": 4183.0}}, "237": {"to_node_id": "1577016", "from_node_id": "1576676", "b2": {"y": 3632.0, "x": 4129.669190203266}, "b1": {"y": 3632.0, "x": 4156.897300677553}}, "233": {"to_node_id": "1577015", "from_node_id": "1577016", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b1761", "name": "gdhA"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "glu__L_c"}, {"coefficient": -1.0, "bigg_id": "nadp_c"}, {"coefficient": 1.0, "bigg_id": "nh4_c"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": 1.0, "bigg_id": "nadph_c"}, {"coefficient": 1.0, "bigg_id": "akg_c"}, {"coefficient": -1.0, "bigg_id": "h2o_c"}], "label_x": 4025.81298828125, "label_y": 3671.95703125, "gene_reaction_rule": "b1761"}, "1576773": {"name": "ATP synthase (four protons for one ATP)", "bigg_id": "ATPS4r", "segments": {"245": {"to_node_id": "1577017", "from_node_id": "1576681", "b2": {"y": 1150.0, "x": 4746.487950057818}, "b1": {"y": 1332.100830078125, "x": 4877.134963734394}}, "244": {"to_node_id": "1577017", "from_node_id": "1576680", "b2": {"y": 1150.0, "x": 4729.0}, "b1": {"y": 1150.0, "x": 4785.0}}, "247": {"to_node_id": "1576682", "from_node_id": "1577018", "b2": {"y": 1150.0, "x": 4520.0}, "b1": {"y": 1148.3885498046875, "x": 4558.046875}}, "246": {"to_node_id": "1577017", "from_node_id": "1576536", "b2": {"y": 1150.0, "x": 4796.204440681362}, "b1": {"y": 1523.8707275390625, "x": 4965.504060083706}}, "243": {"to_node_id": "1577018", "from_node_id": "1577019", "b2": null, "b1": null}, "242": {"to_node_id": "1577019", "from_node_id": "1577017", "b2": null, "b1": null}, "249": {"to_node_id": "1576534", "from_node_id": "1577018", "b2": {"y": 1043.64013671875, "x": 4324.116846450839}, "b1": {"y": 1148.3885498046875, "x": 4366.332368388376}}, "248": {"to_node_id": "1576683", "from_node_id": "1577018", "b2": {"y": 1150.0, "x": 4542.7265625}, "b1": {"y": 1148.388427734375, "x": 4575.66162109375}}}, "genes": [{"bigg_id": "b3731", "name": "atpC"}, {"bigg_id": "b3738", "name": "atpB"}, {"bigg_id": "b3733", "name": "atpG"}, {"bigg_id": "b3739", "name": "atpI"}, {"bigg_id": "b3734", "name": "atpA"}, {"bigg_id": "b3736", "name": "atpF"}, {"bigg_id": "b3737", "name": "atpE"}, {"bigg_id": "b3735", "name": "atpH"}, {"bigg_id": "b3732", "name": "atpD"}], "reversibility": true, "metabolites": [{"coefficient": -4.0, "bigg_id": "h_e"}, {"coefficient": 1.0, "bigg_id": "atp_c"}, {"coefficient": 3.0, "bigg_id": "h_c"}, {"coefficient": -1.0, "bigg_id": "adp_c"}, {"coefficient": -1.0, "bigg_id": "pi_c"}, {"coefficient": 1.0, "bigg_id": "h2o_c"}], "label_x": 4558.97119140625, "label_y": 1122.273193359375, "gene_reaction_rule": "((b3736 and b3737 and b3738) and (b3731 and b3732 and b3733 and b3734 and b3735)) or ((b3736 and b3737 and b3738) and (b3731 and b3732 and b3733 and b3734 and b3735) and b3739)"}, "1576770": {"name": "Fumarate exchange", "bigg_id": "EX_fum_e", "segments": {"225": {"to_node_id": "1577009", "from_node_id": "1576657", "b2": {"y": 560.0, "x": 2840.0}, "b1": {"y": 623.0, "x": 2840.0}}}, "genes": [], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "fum_e"}], "label_x": 2915.057373046875, "label_y": 529.8175659179688, "gene_reaction_rule": ""}, "1576771": {"name": "Succinate transport via proton symport  2 H ", "bigg_id": "SUCCt2_2", "segments": {"229": {"to_node_id": "1577013", "from_node_id": "1576673", "b2": {"y": 3027.0, "x": 4806.816653826392}, "b1": {"y": 3027.0, "x": 4832.0555127546395}}, "228": {"to_node_id": "1577012", "from_node_id": "1577011", "b2": null, "b1": null}, "227": {"to_node_id": "1577011", "from_node_id": "1577013", "b2": null, "b1": null}, "230": {"to_node_id": "1577013", "from_node_id": "1576531", "b2": {"y": 3027.0, "x": 4826.039349194016}, "b1": {"y": 3027.0, "x": 4896.1311639800515}}, "231": {"to_node_id": "1576533", "from_node_id": "1577012", "b2": {"y": 3027.0, "x": 3972.294403079054}, "b1": {"y": 3027.0, "x": 4366.8883209237165}}, "232": {"to_node_id": "1576674", "from_node_id": "1577012", "b2": {"y": 3027.0, "x": 4486.0}, "b1": {"y": 3027.0, "x": 4521.0}}}, "genes": [{"bigg_id": "b3528", "name": "dctA"}], "reversibility": false, "metabolites": [{"coefficient": 1.0, "bigg_id": "succ_c"}, {"coefficient": -1.0, "bigg_id": "succ_e"}, {"coefficient": 2.0, "bigg_id": "h_c"}, {"coefficient": -2.0, "bigg_id": "h_e"}], "label_x": 4501.95703125, "label_y": 2997.661865234375, "gene_reaction_rule": "b3528"}, "1576708": {"name": "L-Glutamine exchange", "bigg_id": "EX_gln__L_e", "segments": {"365": {"to_node_id": "1576868", "from_node_id": "1576537", "b2": {"y": 4158.0, "x": 4951.0}, "b1": {"y": 4158.0, "x": 4902.7}}}, "genes": [], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "gln__L_e"}], "label_x": 4933.3095703125, "label_y": 4131.884765625, "gene_reaction_rule": ""}, "1576703": {"name": "Ammonia reversible transport", "bigg_id": "NH4t", "segments": {"347": {"to_node_id": "1576858", "from_node_id": "1576526", "b2": {"y": 4677.5, "x": 3989.0}, "b1": {"y": 4733.15, "x": 3989.0}}, "348": {"to_node_id": "1576527", "from_node_id": "1576858", "b2": {"y": 4519.5, "x": 3989.0}, "b1": {"y": 4574.45, "x": 3989.0}}}, "genes": [{"bigg_id": "b0451", "name": "amtB"}, {"bigg_id": "s0001", "name": "None"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "nh4_e"}, {"coefficient": 1.0, "bigg_id": "nh4_c"}], "label_x": 3999.0, "label_y": 4588.0, "gene_reaction_rule": "s0001 or b0451"}, "1576702": {"name": "Glucose-6-phosphate isomerase", "bigg_id": "PGI", "segments": {"345": {"to_node_id": "1576857", "from_node_id": "1576524", "b2": {"y": 1330.0, "x": 1055.0}, "b1": {"y": 1284.5, "x": 1055.0}}, "346": {"to_node_id": "1576525", "from_node_id": "1576857", "b2": {"y": 1470.0, "x": 1055.0}, "b1": {"y": 1417.5, "x": 1055.0}}}, "genes": [{"bigg_id": "b4025", "name": "pgi"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "g6p_c"}, {"coefficient": 1.0, "bigg_id": "f6p_c"}], "label_x": 1065.0, "label_y": 1385.0, "gene_reaction_rule": "b4025"}, "1576701": {"name": "Enolase", "bigg_id": "ENO", "segments": {"344": {"to_node_id": "1576523", "from_node_id": "1576855", "b2": {"y": 3319.0832691319597, "x": 1055.0}, "b1": {"y": 3281.224980739588, "x": 1055.0}}, "341": {"to_node_id": "1576856", "from_node_id": "1576522", "b2": {"y": 3175.0, "x": 1055.0}, "b1": {"y": 3173.322021484375, "x": 1055.0}}, "342": {"to_node_id": "1576855", "from_node_id": "1576856", "b2": null, "b1": null}, "343": {"to_node_id": "1576517", "from_node_id": "1576855", "b2": {"y": 3320.0, "x": 1055.0}, "b1": {"y": 3281.5, "x": 1055.0}}}, "genes": [{"bigg_id": "b2779", "name": "eno"}], "reversibility": true, "metabolites": [{"coefficient": 1.0, "bigg_id": "pep_c"}, {"coefficient": 1.0, "bigg_id": "h2o_c"}, {"coefficient": -1.0, "bigg_id": "2pg_c"}], "label_x": 1065.0, "label_y": 3215.0, "gene_reaction_rule": "b2779"}, "1576700": {"name": "Phosphoenolpyruvate carboxylase", "bigg_id": "PPC", "segments": {"339": {"to_node_id": "1576520", "from_node_id": "1576853", "b2": {"y": 3552.157197214914, "x": 1572.3763206054002}, "b1": {"y": 3528.947159164474, "x": 1516.81289618162}}, "338": {"to_node_id": "1576519", "from_node_id": "1576853", "b2": {"y": 3543.994528732819, "x": 1552.8353869664456}, "b1": {"y": 3526.498358619846, "x": 1510.9506160899336}}, "335": {"to_node_id": "1576854", "from_node_id": "1576516", "b2": {"y": 3452.2308899862983, "x": 1334.4013835391315}, "b1": {"y": 3438.769633287661, "x": 1302.6712784637714}}, "334": {"to_node_id": "1576853", "from_node_id": "1576852", "b2": null, "b1": null}, "337": {"to_node_id": "1576854", "from_node_id": "1576518", "b2": {"y": 3447.322871456709, "x": 1322.8324827193853}, "b1": {"y": 3422.409571522363, "x": 1264.1082757312843}}, "336": {"to_node_id": "1576854", "from_node_id": "1576517", "b2": {"y": 3440.1599283734054, "x": 1305.9484025944557}, "b1": {"y": 3398.5330945780183, "x": 1207.828008648186}}, "333": {"to_node_id": "1576852", "from_node_id": "1576854", "b2": null, "b1": null}, "340": {"to_node_id": "1576521", "from_node_id": "1576853", "b2": {"y": 3691.624192938869, "x": 2580.289220436279}, "b1": {"y": 3708.0419942097856, "x": 1966.279649431665}}}, "genes": [{"bigg_id": "b3956", "name": "ppc"}], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "h2o_c"}, {"coefficient": 1.0, "bigg_id": "oaa_c"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": -1.0, "bigg_id": "pep_c"}, {"coefficient": 1.0, "bigg_id": "pi_c"}, {"coefficient": -1.0, "bigg_id": "co2_c"}], "label_x": 1490.0008544921875, "label_y": 3479.666748046875, "gene_reaction_rule": "b3956"}, "1576707": {"name": "Adenylate kinase", "bigg_id": "ADK1", "segments": {"364": {"to_node_id": "1576867", "from_node_id": "1576535", "b2": {"y": 1177.1034937162894, "x": 4145.0}, "b1": {"y": 1123.6783123876312, "x": 4145.0}}, "362": {"to_node_id": "1576536", "from_node_id": "1576866", "b2": {"y": 1441.4029541015625, "x": 4146.15869140625}, "b1": {"y": 1352.2913818359375, "x": 4145.83056640625}}, "363": {"to_node_id": "1576867", "from_node_id": "1576534", "b2": {"y": 1173.8036262051405, "x": 4145.0}, "b1": {"y": 1112.6787540171351, "x": 4145.0}}, "361": {"to_node_id": "1576866", "from_node_id": "1576867", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b0474", "name": "adk"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "amp_c"}, {"coefficient": -1.0, "bigg_id": "atp_c"}, {"coefficient": 2.0, "bigg_id": "adp_c"}], "label_x": 3997.07177734375, "label_y": 1251.6114501953125, "gene_reaction_rule": "b0474"}, "1576706": {"name": "Isocitrate lyase", "bigg_id": "ICL", "segments": {"357": {"to_node_id": "1576865", "from_node_id": "1576505", "b2": {"y": 3916.5, "x": 3415.0}, "b1": {"y": 3958.15, "x": 3413.6}}, "360": {"to_node_id": "1576533", "from_node_id": "1576864", "b2": {"y": 3316.4974972260998, "x": 3417.0}, "b1": {"y": 3631.14924916783, "x": 3417.0}}, "359": {"to_node_id": "1576532", "from_node_id": "1576864", "b2": {"y": 3612.2266277927156, "x": 3417.0}, "b1": {"y": 3719.8679883378145, "x": 3417.0}}, "358": {"to_node_id": "1576864", "from_node_id": "1576865", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b4015", "name": "aceA"}], "reversibility": false, "metabolites": [{"coefficient": 1.0, "bigg_id": "succ_c"}, {"coefficient": 1.0, "bigg_id": "glx_c"}, {"coefficient": -1.0, "bigg_id": "icit_c"}], "label_x": 3427.0, "label_y": 3847.0, "gene_reaction_rule": "b4015"}, "1576705": {"name": "Succinate exchange", "bigg_id": "EX_succ_e", "segments": {"355": {"to_node_id": "1576863", "from_node_id": "1576531", "b2": {"y": 2880.0, "x": 4978.5}, "b1": {"y": 2880.0, "x": 4945.95}}}, "genes": [], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "succ_e"}], "label_x": 4968.927734375, "label_y": 2845.8271484375, "gene_reaction_rule": ""}, "1576704": {"name": "Fructose-bisphosphatase", "bigg_id": "FBP", "segments": {"354": {"to_node_id": "1576530", "from_node_id": "1576860", "b2": {"y": 1600.9687576256715, "x": 835.0}, "b1": {"y": 1645.7906272877015, "x": 835.0}}, "353": {"to_node_id": "1576525", "from_node_id": "1576860", "b2": {"y": 1539.7003591385833, "x": 835.0}, "b1": {"y": 1627.410107741575, "x": 835.0}}, "352": {"to_node_id": "1576861", "from_node_id": "1576529", "b2": {"y": 1805.8044115262064, "x": 835.0}, "b1": {"y": 1901.0147050873545, "x": 835.0}}, "351": {"to_node_id": "1576861", "from_node_id": "1576528", "b2": {"y": 1782.1026313764871, "x": 835.0}, "b1": {"y": 1822.0087712549569, "x": 835.0}}, "350": {"to_node_id": "1576860", "from_node_id": "1576859", "b2": null, "b1": null}, "349": {"to_node_id": "1576859", "from_node_id": "1576861", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b4232", "name": "fbp"}, {"bigg_id": "b3925", "name": "glpX"}], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "fdp_c"}, {"coefficient": -1.0, "bigg_id": "h2o_c"}, {"coefficient": 1.0, "bigg_id": "pi_c"}, {"coefficient": 1.0, "bigg_id": "f6p_c"}], "label_x": 751.3809814453125, "label_y": 1733.561767578125, "gene_reaction_rule": "b3925 or b4232"}, "1577548": {"name": "Aconitase (half-reaction A, Citrate hydro-lyase)", "bigg_id": "ACONTa", "segments": {"511": {"to_node_id": "1576685", "from_node_id": "1577099", "b2": {"y": 4010.3555557486548, "x": 3025.1432055426353}, "b1": {"y": 4012.0956406322803, "x": 3025.7810749583687}}, "507": {"to_node_id": "1577100", "from_node_id": "1577099", "b2": null, "b1": null}, "510": {"to_node_id": "1577103", "from_node_id": "1577101", "b2": {"y": 4045.94073519232, "x": 3126.6630443215304}, "b1": {"y": 4044.2013827305695, "x": 3108.646756937047}}, "508": {"to_node_id": "1577100", "from_node_id": "1577101", "b2": null, "b1": null}, "509": {"to_node_id": "1577102", "from_node_id": "1577101", "b2": {"y": 3993.9154608910203, "x": 3112.4765239553985}, "b1": {"y": 4044.558477078102, "x": 3125.4142208172407}}}, "genes": [{"bigg_id": "b0118", "name": "acnB"}, {"bigg_id": "b1276", "name": "acnA"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "cit_c"}, {"coefficient": 1.0, "bigg_id": "h2o_c"}, {"coefficient": 1.0, "bigg_id": "acon_C_c"}], "label_x": 2982.991259697708, "label_y": 4088.6436288689247, "gene_reaction_rule": "b0118 or b1276"}, "1577549": {"name": "Aconitase (half-reaction B, Isocitrate hydro-lyase)", "bigg_id": "ACONTb", "segments": {"513": {"to_node_id": "1577105", "from_node_id": "1577106", "b2": null, "b1": null}, "512": {"to_node_id": "1577105", "from_node_id": "1577104", "b2": null, "b1": null}, "515": {"to_node_id": "1576505", "from_node_id": "1577106", "b2": {"y": 4013.1918298584474, "x": 3345.4226198631072}, "b1": {"y": 4014.8024620364417, "x": 3344.105236291347}}, "514": {"to_node_id": "1577102", "from_node_id": "1577104", "b2": {"y": 3991.5491179659602, "x": 3266.0226278968735}, "b1": {"y": 4044.360816430351, "x": 3261.354277099013}}, "516": {"to_node_id": "1577103", "from_node_id": "1577104", "b2": {"y": 4046.222560627323, "x": 3260.813883986344}, "b1": {"y": 4046.056264386829, "x": 3262.862957011229}}}, "genes": [{"bigg_id": "b1276", "name": "acnA"}, {"bigg_id": "b0118", "name": "acnB"}], "reversibility": true, "metabolites": [{"coefficient": 1.0, "bigg_id": "icit_c"}, {"coefficient": -1.0, "bigg_id": "h2o_c"}, {"coefficient": -1.0, "bigg_id": "acon_C_c"}], "label_x": 3291.833217745038, "label_y": 4081.35343547726, "gene_reaction_rule": "b0118 or b1276"}, "1577546": {"name": "D lactate transport via proton symport", "bigg_id": "D_LACt2", "segments": {"476": {"to_node_id": "1577068", "from_node_id": "1577067", "b2": null, "b1": null}, "477": {"to_node_id": "1577068", "from_node_id": "1577069", "b2": null, "b1": null}, "478": {"to_node_id": "1576556", "from_node_id": "1577067", "b2": {"y": 4736.89501953125, "x": 1054.9998779296875}, "b1": {"y": 4692.98193359375, "x": 1055.0}}, "479": {"to_node_id": "1577071", "from_node_id": "1577067", "b2": {"y": 4715.98193359375, "x": 1076.0}, "b1": {"y": 4696.98193359375, "x": 1055.0}}, "481": {"to_node_id": "1577072", "from_node_id": "1577069", "b2": {"y": 4451.7353515625, "x": 1074.4132080078125}, "b1": {"y": 4470.7353515625, "x": 1053.4132080078125}}, "480": {"to_node_id": "1576584", "from_node_id": "1577069", "b2": {"y": 4413.36767578125, "x": 1055.0}, "b1": {"y": 4474.7353515625, "x": 1053.4132080078125}}}, "genes": [{"bigg_id": "b3603", "name": "lldP"}, {"bigg_id": "b2975", "name": "glcA"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "lac__D_e"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": 1.0, "bigg_id": "lac__D_c"}, {"coefficient": -1.0, "bigg_id": "h_e"}], "label_x": 1078.65283203125, "label_y": 4609.72607421875, "gene_reaction_rule": "b2975 or b3603"}, "1576711": {"name": "Transaldolase", "bigg_id": "TALA", "segments": {"369": {"to_node_id": "1576872", "from_node_id": "1576873", "b2": null, "b1": null}, "371": {"to_node_id": "1576873", "from_node_id": "1576545", "b2": {"y": 1856.1727017464573, "x": 2173.815906732547}, "b1": {"y": 1892.1518443631908, "x": 2283.184776999114}}, "370": {"to_node_id": "1576874", "from_node_id": "1576872", "b2": null, "b1": null}, "373": {"to_node_id": "1576547", "from_node_id": "1576874", "b2": {"y": 2171.7496092324754, "x": 2178.0}, "b1": {"y": 2076.976957965055, "x": 2178.0}}, "372": {"to_node_id": "1576873", "from_node_id": "1576546", "b2": {"y": 1856.1728238167698, "x": 2175.402576654422}, "b1": {"y": 1890.5651744413158, "x": 2064.2112662569266}}, "374": {"to_node_id": "1576548", "from_node_id": "1576874", "b2": {"y": 2170.2455578331073, "x": 2178.000244140625}, "b1": {"y": 2077.4778177405574, "x": 2178.0}}}, "genes": [{"bigg_id": "b2464", "name": "talA"}, {"bigg_id": "b0008", "name": "talB"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "s7p_c"}, {"coefficient": -1.0, "bigg_id": "g3p_c"}, {"coefficient": 1.0, "bigg_id": "f6p_c"}, {"coefficient": 1.0, "bigg_id": "e4p_c"}], "label_x": 2197.5205078125, "label_y": 2008.8013916015625, "gene_reaction_rule": "b2464 or b0008"}, "1576712": {"name": "Pyruvate kinase", "bigg_id": "PYK", "segments": {"380": {"to_node_id": "1576511", "from_node_id": "1576877", "b2": {"y": 3845.0, "x": 1055.0}, "b1": {"y": 3775.0, "x": 1055.0}}, "381": {"to_node_id": "1576551", "from_node_id": "1576877", "b2": {"y": 3802.008771254957, "x": 1055.0}, "b1": {"y": 3762.102631376487, "x": 1055.0}}, "379": {"to_node_id": "1576875", "from_node_id": "1576517", "b2": {"y": 3613.0, "x": 1055.0}, "b1": {"y": 3515.0, "x": 1055.0}}, "378": {"to_node_id": "1576875", "from_node_id": "1576550", "b2": {"y": 3634.8195639293895, "x": 1055.0}, "b1": {"y": 3587.7318797646312, "x": 1055.0}}, "375": {"to_node_id": "1576876", "from_node_id": "1576875", "b2": null, "b1": null}, "377": {"to_node_id": "1576875", "from_node_id": "1576549", "b2": {"y": 3640.769750529242, "x": 1055.0}, "b1": {"y": 3607.5658350974745, "x": 1055.0}}, "376": {"to_node_id": "1576877", "from_node_id": "1576876", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b1854", "name": "pykA"}, {"bigg_id": "b1676", "name": "pykF"}], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "pep_c"}, {"coefficient": -1.0, "bigg_id": "adp_c"}, {"coefficient": 1.0, "bigg_id": "pyr_c"}, {"coefficient": 1.0, "bigg_id": "atp_c"}, {"coefficient": -1.0, "bigg_id": "h_c"}], "label_x": 1065.0, "label_y": 3695.0, "gene_reaction_rule": "b1854 or b1676"}, "1576713": {"name": "L glutamate transport via proton symport  reversible", "bigg_id": "GLUt2r", "segments": {"382": {"to_node_id": "1576878", "from_node_id": "1576880", "b2": null, "b1": null}, "383": {"to_node_id": "1576879", "from_node_id": "1576878", "b2": null, "b1": null}, "384": {"to_node_id": "1576880", "from_node_id": "1576552", "b2": {"y": 3635.0, "x": 4794.600721137178}, "b1": {"y": 3635.0, "x": 4831.002403790594}}, "385": {"to_node_id": "1576880", "from_node_id": "1576553", "b2": {"y": 3635.0, "x": 4791.314625451064}, "b1": {"y": 3635.0, "x": 4820.0487515035475}}, "386": {"to_node_id": "1576554", "from_node_id": "1576879", "b2": {"y": 3635.0, "x": 4394.492321020364}, "b1": {"y": 3635.0, "x": 4497.047696306109}}, "387": {"to_node_id": "1576555", "from_node_id": "1576879", "b2": {"y": 3635.0, "x": 4499.835695074495}, "b1": {"y": 3635.0, "x": 4528.650708522348}}}, "genes": [{"bigg_id": "b4077", "name": "gltP"}], "reversibility": true, "metabolites": [{"coefficient": 1.0, "bigg_id": "glu__L_c"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": -1.0, "bigg_id": "glu__L_e"}, {"coefficient": -1.0, "bigg_id": "h_e"}], "label_x": 4655.0, "label_y": 3625.0, "gene_reaction_rule": "b4077"}, "1576714": {"name": "D-lactate exchange", "bigg_id": "EX_lac__D_e", "segments": {"388": {"to_node_id": "1576881", "from_node_id": "1576556", "b2": {"y": 4880.0, "x": 1055.0}, "b1": {"y": 4861.19384765625, "x": 1055.0}}}, "genes": [], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "lac__D_e"}], "label_x": 1065.0, "label_y": 4915.0, "gene_reaction_rule": ""}, "1576715": {"name": "Pyruvate exchange", "bigg_id": "EX_pyr_e", "segments": {"390": {"to_node_id": "1576884", "from_node_id": "1576557", "b2": {"y": 3945.0, "x": 215.0}, "b1": {"y": 3945.0, "x": 257.0}}}, "genes": [], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "pyr_e"}], "label_x": 96.76921081542969, "label_y": 3904.851318359375, "gene_reaction_rule": ""}, "1576716": {"name": "Ribulose 5-phosphate 3-epimerase", "bigg_id": "RPE", "segments": {"393": {"to_node_id": "1576558", "from_node_id": "1576885", "b2": {"y": 1485.0, "x": 1995.0}, "b1": {"y": 1436.0, "x": 2030.0}}, "392": {"to_node_id": "1576885", "from_node_id": "1576493", "b2": {"y": 1340.0, "x": 2100.0}, "b1": {"y": 1287.5, "x": 2138.5}}}, "genes": [{"bigg_id": "b4301", "name": "sgcE"}, {"bigg_id": "b3386", "name": "rpe"}], "reversibility": true, "metabolites": [{"coefficient": 1.0, "bigg_id": "xu5p__D_c"}, {"coefficient": -1.0, "bigg_id": "ru5p__D_c"}], "label_x": 1937.57958984375, "label_y": 1422.4544677734375, "gene_reaction_rule": "b3386 or b4301"}, "1576717": {"name": "H+ exchange", "bigg_id": "EX_h_e", "segments": {"394": {"to_node_id": "1576887", "from_node_id": "1576559", "b2": {"y": 2229.5, "x": 4918.0}, "b1": {"y": 2229.15, "x": 4870.4}}}, "genes": [], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "h_e"}], "label_x": 4920.2587890625, "label_y": 2195.827392578125, "gene_reaction_rule": ""}, "1576761": {"name": "Glutamate synthase (NADPH)", "bigg_id": "GLUSy", "segments": {"184": {"to_node_id": "1576554", "from_node_id": "1576987", "b2": {"y": 3721.4298613416263, "x": 4116.0}, "b1": {"y": 3810.0289584024877, "x": 4116.0}}, "182": {"to_node_id": "1576986", "from_node_id": "1576655", "b2": {"y": 3907.2123007471773, "x": 4116.0}, "b1": {"y": 3952.041002490592, "x": 4116.0}}, "183": {"to_node_id": "1576656", "from_node_id": "1576987", "b2": {"y": 3790.445677833893, "x": 4116.0}, "b1": {"y": 3830.733703350168, "x": 4116.0}}, "180": {"to_node_id": "1576986", "from_node_id": "1576654", "b2": {"y": 3902.6240384299276, "x": 4116.0}, "b1": {"y": 3936.7467947664254, "x": 4116.0}}, "181": {"to_node_id": "1576986", "from_node_id": "1576578", "b2": {"y": 3924.538472874492, "x": 4116.0}, "b1": {"y": 4009.7949095816407, "x": 4116.0}}, "179": {"to_node_id": "1576986", "from_node_id": "1576509", "b2": {"y": 4155.746259618145, "x": 4119.22314453125}, "b1": {"y": 4145.014875810485, "x": 3943.568359375}}, "178": {"to_node_id": "1576987", "from_node_id": "1576988", "b2": null, "b1": null}, "177": {"to_node_id": "1576988", "from_node_id": "1576986", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b3212", "name": "gltB"}, {"bigg_id": "b3213", "name": "gltD"}], "reversibility": false, "metabolites": [{"coefficient": 2.0, "bigg_id": "glu__L_c"}, {"coefficient": 1.0, "bigg_id": "nadp_c"}, {"coefficient": -1.0, "bigg_id": "h_c"}, {"coefficient": -1.0, "bigg_id": "nadph_c"}, {"coefficient": -1.0, "bigg_id": "gln__L_c"}, {"coefficient": -1.0, "bigg_id": "akg_c"}], "label_x": 3984.18701171875, "label_y": 3851.553955078125, "gene_reaction_rule": "b3212 and b3213"}, "1577490": {"name": "Acetaldehyde dehydrogenase (acetylating)", "bigg_id": "ACALD", "segments": {"280": {"to_node_id": "1576812", "from_node_id": "1577033", "b2": {"y": 3945.0, "x": 1918.1029079843004}, "b1": {"y": 3945.0, "x": 1961.4308723952902}}, "273": {"to_node_id": "1577032", "from_node_id": "1577031", "b2": null, "b1": null}, "274": {"to_node_id": "1577033", "from_node_id": "1577032", "b2": null, "b1": null}, "275": {"to_node_id": "1577031", "from_node_id": "1576817", "b2": {"y": 3945.0, "x": 2065.5}, "b1": {"y": 3945.0, "x": 2125.0}}, "276": {"to_node_id": "1577031", "from_node_id": "1576825", "b2": {"y": 3945.0, "x": 2058.56912760471}, "b1": {"y": 3945.0, "x": 2101.8970920157}}, "277": {"to_node_id": "1577031", "from_node_id": "1576828", "b2": {"y": 3945.0, "x": 2053.52081728299}, "b1": {"y": 3945.0, "x": 2085.0693909433}}, "278": {"to_node_id": "1576514", "from_node_id": "1577033", "b2": {"y": 3945.0, "x": 1847.5}, "b1": {"y": 3945.0, "x": 1940.25}}, "279": {"to_node_id": "1576832", "from_node_id": "1577033", "b2": {"y": 3945.0, "x": 1934.9306090567002}, "b1": {"y": 3945.0, "x": 1966.47918271701}}}, "genes": [{"bigg_id": "b1241", "name": "adhE"}, {"bigg_id": "b0351", "name": "mhpF"}], "reversibility": true, "metabolites": [{"coefficient": 1.0, "bigg_id": "nadh_c"}, {"coefficient": -1.0, "bigg_id": "coa_c"}, {"coefficient": -1.0, "bigg_id": "acald_c"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": -1.0, "bigg_id": "nad_c"}, {"coefficient": 1.0, "bigg_id": "accoa_c"}], "label_x": 1939.0750732421875, "label_y": 3998.470458984375, "gene_reaction_rule": "b0351 or b1241"}, "1577497": {"name": "Acetaldehyde reversible transport", "bigg_id": "ACALDt", "segments": {"281": {"to_node_id": "1577034", "from_node_id": "1576815", "b2": {"y": 4707.0, "x": 2210.0}, "b1": {"y": 4796.55283203125, "x": 2210.0}}, "282": {"to_node_id": "1576817", "from_node_id": "1577034", "b2": {"y": 4257.5, "x": 2210.0}, "b1": {"y": 4476.25, "x": 2210.0}}}, "genes": [{"bigg_id": "s0001", "name": "None"}], "reversibility": true, "metabolites": [{"coefficient": 1.0, "bigg_id": "acald_c"}, {"coefficient": -1.0, "bigg_id": "acald_e"}], "label_x": 2248.561767578125, "label_y": 4579.041015625, "gene_reaction_rule": "s0001"}, "1577498": {"name": "Acetaldehyde exchange", "bigg_id": "EX_acald_e", "segments": {"283": {"to_node_id": "1577035", "from_node_id": "1576815", "b2": {"y": 4894.0, "x": 2210.5}, "b1": {"y": 4889.1484375, "x": 2210.15}}}, "genes": [], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "acald_e"}], "label_x": 2227.346923828125, "label_y": 4922.892578125, "gene_reaction_rule": ""}, "1576724": {"name": "Glutamine synthetase", "bigg_id": "GLNS", "segments": {"424": {"to_node_id": "1576578", "from_node_id": "1576899", "b2": {"y": 4007.2677048056653, "x": 4364.0}, "b1": {"y": 3924.4803114416995, "x": 4364.0}}, "421": {"to_node_id": "1576901", "from_node_id": "1576554", "b2": {"y": 3812.091159595566, "x": 4364.0}, "b1": {"y": 3725.970531985219, "x": 4364.0}}, "420": {"to_node_id": "1576899", "from_node_id": "1576900", "b2": null, "b1": null}, "423": {"to_node_id": "1576901", "from_node_id": "1576577", "b2": {"y": 3835.8273009599397, "x": 4364.0}, "b1": {"y": 3805.0910031997996, "x": 4364.0}}, "422": {"to_node_id": "1576901", "from_node_id": "1576576", "b2": {"y": 3830.8679841164862, "x": 4364.0}, "b1": {"y": 3788.5599470549537, "x": 4364.0}}, "425": {"to_node_id": "1576579", "from_node_id": "1576899", "b2": {"y": 3936.762432936357, "x": 4364.0}, "b1": {"y": 3903.3287298809073, "x": 4364.0}}, "419": {"to_node_id": "1576900", "from_node_id": "1576901", "b2": null, "b1": null}, "427": {"to_node_id": "1576581", "from_node_id": "1576899", "b2": {"y": 3978.617241644675, "x": 4364.0}, "b1": {"y": 3915.8851724934025, "x": 4364.0}}, "426": {"to_node_id": "1576580", "from_node_id": "1576899", "b2": {"y": 3956.314560089181, "x": 4364.0}, "b1": {"y": 3909.1943680267545, "x": 4364.0}}}, "genes": [{"bigg_id": "b3870", "name": "glnA"}, {"bigg_id": "b1297", "name": "puuA"}], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "glu__L_c"}, {"coefficient": -1.0, "bigg_id": "atp_c"}, {"coefficient": -1.0, "bigg_id": "nh4_c"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": 1.0, "bigg_id": "adp_c"}, {"coefficient": 1.0, "bigg_id": "pi_c"}, {"coefficient": 1.0, "bigg_id": "gln__L_c"}], "label_x": 4377.22314453125, "label_y": 3875.114990234375, "gene_reaction_rule": "b3870 or b1297"}, "1576727": {"name": "2-Oxogluterate dehydrogenase", "bigg_id": "AKGDH", "segments": {"443": {"to_node_id": "1576908", "from_node_id": "1576585", "b2": {"y": 3494.907757737772, "x": 3779.4266247023934}, "b1": {"y": 3529.6925257925727, "x": 3778.088749007978}}, "442": {"to_node_id": "1576908", "from_node_id": "1576509", "b2": {"y": 3502.6153909632244, "x": 3779.130177270645}, "b1": {"y": 3555.384636544082, "x": 3777.1005909021505}}, "441": {"to_node_id": "1576910", "from_node_id": "1576909", "b2": null, "b1": null}, "440": {"to_node_id": "1576909", "from_node_id": "1576908", "b2": null, "b1": null}, "447": {"to_node_id": "1576588", "from_node_id": "1576910", "b2": {"y": 3276.99346892041, "x": 3770.846587256151}, "b1": {"y": 3314.098040676123, "x": 3774.453976176845}}, "446": {"to_node_id": "1576587", "from_node_id": "1576910", "b2": {"y": 3277.236984619066, "x": 3770.8702623935205}, "b1": {"y": 3314.1710953857196, "x": 3774.4610787180563}}, "445": {"to_node_id": "1576570", "from_node_id": "1576910", "b2": {"y": 3259.378766045427, "x": 3769.134046698861}, "b1": {"y": 3308.813629813628, "x": 3773.940214009658}}, "444": {"to_node_id": "1576908", "from_node_id": "1576586", "b2": {"y": 3498.5402671676266, "x": 3779.2869128012453}, "b1": {"y": 3541.8008905587553, "x": 3777.623042670817}}}, "genes": [{"bigg_id": "b0116", "name": "lpd"}, {"bigg_id": "b0726", "name": "sucA"}, {"bigg_id": "b0727", "name": "sucB"}], "reversibility": false, "metabolites": [{"coefficient": 1.0, "bigg_id": "nadh_c"}, {"coefficient": -1.0, "bigg_id": "coa_c"}, {"coefficient": -1.0, "bigg_id": "nad_c"}, {"coefficient": 1.0, "bigg_id": "co2_c"}, {"coefficient": 1.0, "bigg_id": "succoa_c"}, {"coefficient": -1.0, "bigg_id": "akg_c"}], "label_x": 3793.0, "label_y": 3392.0, "gene_reaction_rule": "b0116 and b0726 and b0727"}, "1576726": {"name": "NAD transhydrogenase", "bigg_id": "NADTRHD", "segments": {"438": {"to_node_id": "1576496", "from_node_id": "1576905", "b2": {"y": 1270.0, "x": 3400.0}, "b1": {"y": 1270.0, "x": 3449.0}}, "439": {"to_node_id": "1576497", "from_node_id": "1576905", "b2": {"y": 1270.0, "x": 3418.3388104489154}, "b1": {"y": 1270.0, "x": 3446.2829175487373}}, "436": {"to_node_id": "1576906", "from_node_id": "1576501", "b2": {"y": 1270.0, "x": 3592.9455878111676}, "b1": {"y": 1270.0001220703125, "x": 3627.146913797642}}, "437": {"to_node_id": "1576906", "from_node_id": "1576500", "b2": {"y": 1270.0, "x": 3595.5}, "b1": {"y": 1270.0, "x": 3655.0}}, "434": {"to_node_id": "1576907", "from_node_id": "1576906", "b2": null, "b1": null}, "435": {"to_node_id": "1576905", "from_node_id": "1576907", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b1602", "name": "pntB"}, {"bigg_id": "b3962", "name": "sthA"}, {"bigg_id": "b1603", "name": "pntA"}], "reversibility": false, "metabolites": [{"coefficient": 1.0, "bigg_id": "nadh_c"}, {"coefficient": 1.0, "bigg_id": "nadp_c"}, {"coefficient": -1.0, "bigg_id": "nad_c"}, {"coefficient": -1.0, "bigg_id": "nadph_c"}], "label_x": 3478.431396484375, "label_y": 1319.6259765625, "gene_reaction_rule": "b3962 or (b1602 and b1603)"}, "1576721": {"name": "Phosphofructokinase", "bigg_id": "PFK", "segments": {"407": {"to_node_id": "1576893", "from_node_id": "1576572", "b2": {"y": 1674.9065411518764, "x": 1055.0}, "b1": {"y": 1639.6884705062548, "x": 1055.0}}, "406": {"to_node_id": "1576893", "from_node_id": "1576525", "b2": {"y": 1668.25, "x": 1055.0}, "b1": {"y": 1617.5, "x": 1055.0}}, "405": {"to_node_id": "1576892", "from_node_id": "1576891", "b2": null, "b1": null}, "404": {"to_node_id": "1576891", "from_node_id": "1576893", "b2": null, "b1": null}, "410": {"to_node_id": "1576574", "from_node_id": "1576892", "b2": {"y": 1835.2079728939614, "x": 1055.0}, "b1": {"y": 1793.0623918681883, "x": 1055.0}}, "409": {"to_node_id": "1576529", "from_node_id": "1576892", "b2": {"y": 1850.0, "x": 1055.0}, "b1": {"y": 1797.5, "x": 1055.0}}, "408": {"to_node_id": "1576573", "from_node_id": "1576892", "b2": {"y": 1822.4341649025257, "x": 1055.0}, "b1": {"y": 1789.2302494707578, "x": 1055.0}}}, "genes": [{"bigg_id": "b1723", "name": "pfkB"}, {"bigg_id": "b3916", "name": "pfkA"}], "reversibility": false, "metabolites": [{"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": 1.0, "bigg_id": "adp_c"}, {"coefficient": -1.0, "bigg_id": "f6p_c"}, {"coefficient": -1.0, "bigg_id": "atp_c"}, {"coefficient": 1.0, "bigg_id": "fdp_c"}], "label_x": 1065.0, "label_y": 1725.0, "gene_reaction_rule": "b3916 or b1723"}, "1576720": {"name": "Succinyl-CoA synthetase (ADP-forming)", "bigg_id": "SUCOAS", "segments": {"397": {"to_node_id": "1576890", "from_node_id": "1576888", "b2": null, "b1": null}, "396": {"to_node_id": "1576888", "from_node_id": "1576889", "b2": null, "b1": null}, "401": {"to_node_id": "1576569", "from_node_id": "1576890", "b2": {"y": 3112.853617863234, "x": 3706.5785261677484}, "b1": {"y": 3077.95608535897, "x": 3678.1735578503244}}, "400": {"to_node_id": "1576889", "from_node_id": "1576533", "b2": {"y": 2954.5162418879845, "x": 3567.004509117803}, "b1": {"y": 2904.387472959949, "x": 3518.015030392677}}, "403": {"to_node_id": "1576571", "from_node_id": "1576890", "b2": {"y": 3107.574578569538, "x": 3702.2816337193913}, "b1": {"y": 3076.3723735708613, "x": 3676.8844901158172}}, "399": {"to_node_id": "1576889", "from_node_id": "1576568", "b2": {"y": 2964.923830429043, "x": 3577.1755615556553}, "b1": {"y": 2939.079434763476, "x": 3551.9185385188516}}, "398": {"to_node_id": "1576889", "from_node_id": "1576567", "b2": {"y": 2962.1615434463, "x": 3574.4760538225205}, "b1": {"y": 2929.871811487667, "x": 3542.920179408402}}, "402": {"to_node_id": "1576570", "from_node_id": "1576890", "b2": {"y": 3120.815793594307, "x": 3713.059366879087}, "b1": {"y": 3080.344738078292, "x": 3680.117810063726}}}, "genes": [{"bigg_id": "b0729", "name": "sucD"}, {"bigg_id": "b0728", "name": "sucC"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "coa_c"}, {"coefficient": 1.0, "bigg_id": "adp_c"}, {"coefficient": -1.0, "bigg_id": "succ_c"}, {"coefficient": -1.0, "bigg_id": "atp_c"}, {"coefficient": 1.0, "bigg_id": "succoa_c"}, {"coefficient": 1.0, "bigg_id": "pi_c"}], "label_x": 3641.0, "label_y": 3010.0, "gene_reaction_rule": "b0728 and b0729"}, "1576723": {"name": "Transketolase", "bigg_id": "TKT2", "segments": {"414": {"to_node_id": "1576898", "from_node_id": "1576896", "b2": null, "b1": null}, "415": {"to_node_id": "1576897", "from_node_id": "1576547", "b2": {"y": 1735.0, "x": 1772.8736958157247}, "b1": {"y": 1735.0, "x": 1954.5789860524153}}, "416": {"to_node_id": "1576897", "from_node_id": "1576558", "b2": {"y": 1735.0, "x": 1741.208765402248}, "b1": {"y": 1735.0, "x": 1849.0292180074937}}, "417": {"to_node_id": "1576525", "from_node_id": "1576898", "b2": {"y": 1587.43115234375, "x": 1280.4546812716637}, "b1": {"y": 1741.3470458984375, "x": 1235.776382408843}}, "413": {"to_node_id": "1576896", "from_node_id": "1576897", "b2": null, "b1": null}, "418": {"to_node_id": "1576575", "from_node_id": "1576898", "b2": {"y": 1735.0, "x": 1312.7516245895065}, "b1": {"y": 1735.0, "x": 1318.2979239002893}}}, "genes": [{"bigg_id": "b2465", "name": "tktB"}, {"bigg_id": "b2935", "name": "tktA"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "xu5p__D_c"}, {"coefficient": -1.0, "bigg_id": "e4p_c"}, {"coefficient": 1.0, "bigg_id": "g3p_c"}, {"coefficient": 1.0, "bigg_id": "f6p_c"}], "label_x": 1520.71923828125, "label_y": 1702.785400390625, "gene_reaction_rule": "b2935 or b2465"}, "1576722": {"name": "L-Glutamate exchange", "bigg_id": "EX_glu__L_e", "segments": {"411": {"to_node_id": "1576895", "from_node_id": "1576552", "b2": {"y": 3635.0, "x": 4949.0}, "b1": {"y": 3634.3, "x": 4902.8}}}, "genes": [], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "glu__L_e"}], "label_x": 4936.36669921875, "label_y": 3680.79150390625, "gene_reaction_rule": ""}, "1576729": {"name": "O2 exchange", "bigg_id": "EX_o2_e", "segments": {"454": {"to_node_id": "1576914", "from_node_id": "1576494", "b2": {"y": 1660.0, "x": 4910.0}, "b1": {"y": 1660.0, "x": 4868.0}}}, "genes": [], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "o2_e"}], "label_x": 4894.58984375, "label_y": 1633.8848876953125, "gene_reaction_rule": ""}, "1576728": {"name": "Pyruvate formate lyase", "bigg_id": "PFL", "segments": {"449": {"to_node_id": "1576913", "from_node_id": "1576911", "b2": null, "b1": null}, "448": {"to_node_id": "1576911", "from_node_id": "1576912", "b2": null, "b1": null}, "450": {"to_node_id": "1576912", "from_node_id": "1576589", "b2": {"y": 3995.0, "x": 1239.5565547885194}, "b1": {"y": 3995.0, "x": 1203.521849295065}}, "451": {"to_node_id": "1576912", "from_node_id": "1576511", "b2": {"y": 3995.0, "x": 1224.0767078078675}, "b1": {"y": 3995.0, "x": 1151.9223593595584}}, "452": {"to_node_id": "1576514", "from_node_id": "1576913", "b2": {"y": 3995.0, "x": 1567.0690632574556}, "b1": {"y": 3995.0, "x": 1460.6207189772367}}, "453": {"to_node_id": "1576590", "from_node_id": "1576913", "b2": {"y": 3995.0, "x": 1469.8292804986534}, "b1": {"y": 3995.0, "x": 1431.4487841495961}}}, "genes": [{"bigg_id": "b3114", "name": "tdcE"}, {"bigg_id": "b3951", "name": "pflD"}, {"bigg_id": "b3952", "name": "pflC"}, {"bigg_id": "b0903", "name": "pflB"}, {"bigg_id": "b0902", "name": "pflA"}, {"bigg_id": "b2579", "name": "grcA"}], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "pyr_c"}, {"coefficient": -1.0, "bigg_id": "coa_c"}, {"coefficient": 1.0, "bigg_id": "accoa_c"}, {"coefficient": 1.0, "bigg_id": "for_c"}], "label_x": 1310.09130859375, "label_y": 4046.8837890625, "gene_reaction_rule": "((b0902 and b0903) and b2579) or (b0902 and b0903) or (b0902 and b3114) or (b3951 and b3952)"}, "1577532": {"name": "Malate transport via proton symport  2 H ", "bigg_id": "MALt2_2", "segments": {"33": {"to_node_id": "1577056", "from_node_id": "1576831", "b2": {"y": 720.0576036932963, "x": 2610.0}, "b1": {"y": 682.8586789776543, "x": 2610.0}}, "32": {"to_node_id": "1577058", "from_node_id": "1577057", "b2": null, "b1": null}, "31": {"to_node_id": "1577057", "from_node_id": "1577056", "b2": null, "b1": null}, "36": {"to_node_id": "1576504", "from_node_id": "1577058", "b2": {"y": 2086.013675322326, "x": 2610.0}, "b1": {"y": 1311.8041025966977, "x": 2610.0}}, "35": {"to_node_id": "1576810", "from_node_id": "1577058", "b2": {"y": 1032.2015325445527, "x": 2610.0}, "b1": {"y": 995.6604597633658, "x": 2610.0}}, "34": {"to_node_id": "1577056", "from_node_id": "1576816", "b2": {"y": 723.1, "x": 2610.0}, "b1": {"y": 693.0, "x": 2610.0}}}, "genes": [{"bigg_id": "b3528", "name": "dctA"}], "reversibility": false, "metabolites": [{"coefficient": 1.0, "bigg_id": "mal__L_c"}, {"coefficient": 2.0, "bigg_id": "h_c"}, {"coefficient": -1.0, "bigg_id": "mal__L_e"}, {"coefficient": -2.0, "bigg_id": "h_e"}], "label_x": 2623.173583984375, "label_y": 844.3793334960938, "gene_reaction_rule": "b3528"}, "1577537": {"name": "L-Malate exchange", "bigg_id": "EX_mal__L_e", "segments": {"37": {"to_node_id": "1577059", "from_node_id": "1576816", "b2": {"y": 560.0, "x": 2610.0}, "b1": {"y": 623.0, "x": 2610.0}}}, "genes": [], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "mal__L_e"}], "label_x": 2356.597412109375, "label_y": 513.949951171875, "gene_reaction_rule": ""}, "1576732": {"name": "2 oxoglutarate reversible transport via symport", "bigg_id": "AKGt2r", "segments": {"469": {"to_node_id": "1576924", "from_node_id": "1576923", "b2": null, "b1": null}, "472": {"to_node_id": "1576923", "from_node_id": "1576599", "b2": {"y": 3228.0, "x": 4807.306616216525}, "b1": {"y": 3228.0, "x": 4843.0220540550845}}, "473": {"to_node_id": "1576509", "from_node_id": "1576922", "b2": {"y": 3228.0, "x": 4074.584218822}, "b1": {"y": 3228.0, "x": 4373.7752656466}}, "470": {"to_node_id": "1576922", "from_node_id": "1576924", "b2": null, "b1": null}, "471": {"to_node_id": "1576923", "from_node_id": "1576598", "b2": {"y": 3228.0, "x": 4811.5}, "b1": {"y": 3228.0, "x": 4857.0}}, "474": {"to_node_id": "1576600", "from_node_id": "1576922", "b2": {"y": 3228.0, "x": 4449.798467455447}, "b1": {"y": 3228.0, "x": 4486.339540236634}}}, "genes": [{"bigg_id": "b2587", "name": "kgtP"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "h_e"}, {"coefficient": 1.0, "bigg_id": "akg_c"}, {"coefficient": -1.0, "bigg_id": "akg_e"}, {"coefficient": 1.0, "bigg_id": "h_c"}], "label_x": 4594.6474609375, "label_y": 3197.05029296875, "gene_reaction_rule": "b2587"}, "1576733": {"name": "Fructose-bisphosphate aldolase", "bigg_id": "FBA", "segments": {"55": {"to_node_id": "1576601", "from_node_id": "1576925", "b2": {"y": 2081.141357421875, "x": 929.645751953125}, "b1": {"y": 2082.5, "x": 1055.0}}, "54": {"to_node_id": "1576575", "from_node_id": "1576925", "b2": {"y": 2120.0, "x": 1055.0}, "b1": {"y": 2067.5, "x": 1055.0}}, "53": {"to_node_id": "1576925", "from_node_id": "1576926", "b2": null, "b1": null}, "475": {"to_node_id": "1576926", "from_node_id": "1576529", "b2": {"y": 1974.28076171875, "x": 1055.0}, "b1": {"y": 1970.4088134765625, "x": 1055.0}}}, "genes": [{"bigg_id": "b2097", "name": "fbaB"}, {"bigg_id": "b2925", "name": "fbaA"}, {"bigg_id": "b1773", "name": "ydjI"}], "reversibility": true, "metabolites": [{"coefficient": 1.0, "bigg_id": "dhap_c"}, {"coefficient": 1.0, "bigg_id": "g3p_c"}, {"coefficient": -1.0, "bigg_id": "fdp_c"}], "label_x": 969.7942504882812, "label_y": 2031.01611328125, "gene_reaction_rule": "b2097 or b1773 or b2925"}, "1576730": {"name": "Phosphoenolpyruvate carboxykinase", "bigg_id": "PPCK", "segments": {"458": {"to_node_id": "1576917", "from_node_id": "1576591", "b2": {"y": 3557.6148705803193, "x": 1495.4573041787805}, "b1": {"y": 3566.049568601064, "x": 1519.8576805959353}}, "459": {"to_node_id": "1576917", "from_node_id": "1576521", "b2": {"y": 3678.777694102544, "x": 1757.8986662821364}, "b1": {"y": 3758.886258987647, "x": 2521.6033016696215}}, "461": {"to_node_id": "1576593", "from_node_id": "1576918", "b2": {"y": 3483.931701701515, "x": 1277.7951051045454}, "b1": {"y": 3497.2795105104547, "x": 1317.8385315313635}}, "460": {"to_node_id": "1576592", "from_node_id": "1576918", "b2": {"y": 3492.675272400688, "x": 1304.0258172020633}, "b1": {"y": 3499.9025817202064, "x": 1325.707745160619}}, "456": {"to_node_id": "1576916", "from_node_id": "1576917", "b2": null, "b1": null}, "457": {"to_node_id": "1576918", "from_node_id": "1576916", "b2": null, "b1": null}, "462": {"to_node_id": "1576517", "from_node_id": "1576918", "b2": {"y": 3454.321462634956, "x": 1188.9643879048676}, "b1": {"y": 3488.3964387904866, "x": 1291.1893163714603}}}, "genes": [{"bigg_id": "b3403", "name": "pck"}], "reversibility": false, "metabolites": [{"coefficient": 1.0, "bigg_id": "pep_c"}, {"coefficient": -1.0, "bigg_id": "atp_c"}, {"coefficient": -1.0, "bigg_id": "oaa_c"}, {"coefficient": 1.0, "bigg_id": "co2_c"}, {"coefficient": 1.0, "bigg_id": "adp_c"}], "label_x": 1377.3328857421875, "label_y": 3600.33447265625, "gene_reaction_rule": "b3403"}, "1576731": {"name": "Phosphate reversible transport via symport", "bigg_id": "PIt2r", "segments": {"468": {"to_node_id": "1576597", "from_node_id": "1576919", "b2": {"y": 4475.0, "x": 2880.0}, "b1": {"y": 4506.5, "x": 2880.0}}, "465": {"to_node_id": "1576921", "from_node_id": "1576594", "b2": {"y": 4742.1, "x": 2880.0}, "b1": {"y": 4782.0, "x": 2880.0}}, "464": {"to_node_id": "1576919", "from_node_id": "1576920", "b2": null, "b1": null}, "467": {"to_node_id": "1576596", "from_node_id": "1576919", "b2": {"y": 4464.789040942943, "x": 2880.0}, "b1": {"y": 4503.436712282883, "x": 2880.0}}, "466": {"to_node_id": "1576921", "from_node_id": "1576595", "b2": {"y": 4740.280870394058, "x": 2880.0}, "b1": {"y": 4775.936234646861, "x": 2880.0}}, "463": {"to_node_id": "1576920", "from_node_id": "1576921", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b3493", "name": "pitA"}, {"bigg_id": "b2987", "name": "pitB"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "h_e"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": 1.0, "bigg_id": "pi_c"}, {"coefficient": -1.0, "bigg_id": "pi_e"}], "label_x": 2916.97509765625, "label_y": 4649.33837890625, "gene_reaction_rule": "b2987 or b3493"}, "1576736": {"name": "Ribose-5-phosphate isomerase", "bigg_id": "RPI", "segments": {"66": {"to_node_id": "1576931", "from_node_id": "1576605", "b2": {"y": 1490.0, "x": 2362.0}, "b1": {"y": 1535.5, "x": 2401.9}}, "67": {"to_node_id": "1576493", "from_node_id": "1576931", "b2": {"y": 1345.0, "x": 2230.0}, "b1": {"y": 1401.0, "x": 2282.5}}}, "genes": [{"bigg_id": "b2914", "name": "rpiA"}, {"bigg_id": "b4090", "name": "rpiB"}], "reversibility": true, "metabolites": [{"coefficient": 1.0, "bigg_id": "ru5p__D_c"}, {"coefficient": -1.0, "bigg_id": "r5p_c"}], "label_x": 2315.0, "label_y": 1415.0, "gene_reaction_rule": "b2914 or b4090"}, "1576737": {"name": "Malate synthase", "bigg_id": "MALS", "segments": {"75": {"to_node_id": "1576504", "from_node_id": "1576932", "b2": {"y": 3264.9901959981144, "x": 2733.0283686781227}, "b1": {"y": 3318.197058799434, "x": 2810.0085106034367}}, "74": {"to_node_id": "1576609", "from_node_id": "1576932", "b2": {"y": 3288.6581354094164, "x": 2767.2713448476666}, "b1": {"y": 3325.297440622825, "x": 2820.2814034543}}, "73": {"to_node_id": "1576608", "from_node_id": "1576932", "b2": {"y": 3305.691868266011, "x": 2791.915894512527}, "b1": {"y": 3330.4075604798036, "x": 2827.674768353758}}, "72": {"to_node_id": "1576933", "from_node_id": "1576607", "b2": {"y": 3460.23788356471, "x": 3016.1884971205427}, "b1": {"y": 3495.7929452157005, "x": 3067.961657068476}}, "71": {"to_node_id": "1576933", "from_node_id": "1576606", "b2": {"y": 3455.108224908018, "x": 3008.7189941643073}, "b1": {"y": 3478.694083026728, "x": 3043.063313881025}}, "70": {"to_node_id": "1576933", "from_node_id": "1576532", "b2": {"y": 3464.029731004742, "x": 3021.7099591823435}, "b1": {"y": 3508.4324366824735, "x": 3086.3665306078124}}, "68": {"to_node_id": "1576934", "from_node_id": "1576933", "b2": null, "b1": null}, "69": {"to_node_id": "1576932", "from_node_id": "1576934", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b2976", "name": "glcB"}, {"bigg_id": "b4014", "name": "aceB"}], "reversibility": false, "metabolites": [{"coefficient": 1.0, "bigg_id": "coa_c"}, {"coefficient": 1.0, "bigg_id": "h_c"}, {"coefficient": 1.0, "bigg_id": "mal__L_c"}, {"coefficient": -1.0, "bigg_id": "accoa_c"}, {"coefficient": -1.0, "bigg_id": "h2o_c"}, {"coefficient": -1.0, "bigg_id": "glx_c"}], "label_x": 2921.0, "label_y": 3378.0, "gene_reaction_rule": "b4014 or b2976"}, "1576734": {"name": "Triose-phosphate isomerase", "bigg_id": "TPI", "segments": {"57": {"to_node_id": "1576575", "from_node_id": "1576927", "b2": {"y": 2195.0, "x": 1005.0}, "b1": {"y": 2195.0, "x": 970.0}}, "56": {"to_node_id": "1576927", "from_node_id": "1576601", "b2": {"y": 2195.0, "x": 911.3470458984375}, "b1": {"y": 2195.0, "x": 911.255859375}}}, "genes": [{"bigg_id": "b3919", "name": "tpiA"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "dhap_c"}, {"coefficient": 1.0, "bigg_id": "g3p_c"}], "label_x": 936.438232421875, "label_y": 2245.297119140625, "gene_reaction_rule": "b3919"}, "1576735": {"name": "Cytochrome oxidase bd (ubiquinol-8: 2 protons)", "bigg_id": "CYTBD", "segments": {"59": {"to_node_id": "1576929", "from_node_id": "1576928", "b2": null, "b1": null}, "58": {"to_node_id": "1576928", "from_node_id": "1576930", "b2": null, "b1": null}, "60": {"to_node_id": "1576930", "from_node_id": "1576602", "b2": {"y": 1900.0, "x": 4595.5}, "b1": {"y": 1895.1654052734375, "x": 4416.69775390625}}, "61": {"to_node_id": "1576930", "from_node_id": "1576495", "b2": {"y": 1900.0, "x": 4572.371881863104}, "b1": {"y": 1900.0, "x": 4437.906272877015}}, "62": {"to_node_id": "1576930", "from_node_id": "1576542", "b2": {"y": 1900.0, "x": 4581.906341374356}, "b1": {"y": 1890.3310546875, "x": 4368.162902237436}}, "63": {"to_node_id": "1576539", "from_node_id": "1576929", "b2": {"y": 1903.22314453125, "x": 4842.38515985191}, "b1": {"y": 1900.0, "x": 4715.894014752448}}, "64": {"to_node_id": "1576603", "from_node_id": "1576929", "b2": {"y": 1900.0, "x": 4775.0}, "b1": {"y": 1900.0, "x": 4715.5}}, "65": {"to_node_id": "1576604", "from_node_id": "1576929", "b2": {"y": 1758.1868896484375, "x": 4884.545828600423}, "b1": {"y": 1901.611572265625, "x": 4821.203885298877}}}, "genes": [{"bigg_id": "b0978", "name": "cbdA"}, {"bigg_id": "b0734", "name": "cydB"}, {"bigg_id": "b0979", "name": "cbdB"}, {"bigg_id": "b0733", "name": "cydA"}], "reversibility": false, "metabolites": [{"coefficient": -0.5, "bigg_id": "o2_c"}, {"coefficient": 1.0, "bigg_id": "q8_c"}, {"coefficient": 2.0, "bigg_id": "h_e"}, {"coefficient": -1.0, "bigg_id": "q8h2_c"}, {"coefficient": -2.0, "bigg_id": "h_c"}, {"coefficient": 1.0, "bigg_id": "h2o_c"}], "label_x": 4560.4169921875, "label_y": 1954.46044921875, "gene_reaction_rule": "(b0978 and b0979) or (b0733 and b0734)"}, "1576739": {"name": "Phosphotransacetylase", "bigg_id": "PTAr", "segments": {"77": {"to_node_id": "1576936", "from_node_id": "1576937", "b2": null, "b1": null}, "76": {"to_node_id": "1576937", "from_node_id": "1576935", "b2": null, "b1": null}, "80": {"to_node_id": "1576613", "from_node_id": "1576936", "b2": {"y": 4140.0, "x": 1715.0}, "b1": {"y": 4115.5, "x": 1715.0}}, "81": {"to_node_id": "1576614", "from_node_id": "1576936", "b2": {"y": 4157.201532544553, "x": 1715.0}, "b1": {"y": 4120.660459763366, "x": 1715.0}}, "79": {"to_node_id": "1576935", "from_node_id": "1576612", "b2": {"y": 4049.339540236634, "x": 1715.0}, "b1": {"y": 4012.7984674554473, "x": 1715.0}}, "78": {"to_node_id": "1576935", "from_node_id": "1576514", "b2": {"y": 4047.0, "x": 1715.0}, "b1": {"y": 4005.0, "x": 1715.0}}}, "genes": [{"bigg_id": "b2297", "name": "pta"}, {"bigg_id": "b2458", "name": "eutD"}], "reversibility": true, "metabolites": [{"coefficient": -1.0, "bigg_id": "accoa_c"}, {"coefficient": 1.0, "bigg_id": "actp_c"}, {"coefficient": -1.0, "bigg_id": "pi_c"}, {"coefficient": 1.0, "bigg_id": "coa_c"}], "label_x": 1725.0, "label_y": 4075.0, "gene_reaction_rule": "b2297 or b2458"}, "1577529": {"name": "D-Fructose exchange", "bigg_id": "EX_fru_e", "segments": {"29": {"to_node_id": "1577054", "from_node_id": "1576826", "b2": {"y": 1360.0, "x": 241.0}, "b1": {"y": 1360.0, "x": 282.3}}}, "genes": [], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "fru_e"}], "label_x": 125.35597229003906, "label_y": 1321.438232421875, "gene_reaction_rule": ""}, "1577520": {"name": "Fumarate reductase", "bigg_id": "FRD7", "segments": {"20": {"to_node_id": "1577048", "from_node_id": "1576830", "b2": {"y": 2600.0, "x": 3057.152680682408}, "b1": {"y": 2600.0, "x": 3003.842268941361}}, "21": {"to_node_id": "1576814", "from_node_id": "1577050", "b2": {"y": 2600.0, "x": 3213.824115301167}, "b1": {"y": 2600.0, "x": 3162.14723459035}}, "22": {"to_node_id": "1576533", "from_node_id": "1577050", "b2": {"y": 2600.0, "x": 3333.4483135103533}, "b1": {"y": 2600.0, "x": 3198.034494053106}}, "19": {"to_node_id": "1577048", "from_node_id": "1576503", "b2": {"y": 2600.0, "x": 3020.2689151278832}, "b1": {"y": 2600.0, "x": 2880.896383759611}}, "18": {"to_node_id": "1577050", "from_node_id": "1577049", "b2": null, "b1": null}, "17": {"to_node_id": "1577049", "from_node_id": "1577048", "b2": null, "b1": null}}, "genes": [{"bigg_id": "b4152", "name": "frdC"}, {"bigg_id": "b4151", "name": "frdD"}, {"bigg_id": "b4154", "name": "frdA"}, {"bigg_id": "b4153", "name": "frdB"}], "reversibility": false, "metabolites": [{"coefficient": 1.0, "bigg_id": "succ_c"}, {"coefficient": -1.0, "bigg_id": "fum_c"}, {"coefficient": 1.0, "bigg_id": "q8_c"}, {"coefficient": -1.0, "bigg_id": "q8h2_c"}], "label_x": 3078.744384765625, "label_y": 2572.54541015625, "gene_reaction_rule": "b4151 and b4152 and b4153 and b4154"}, "1577524": {"name": "Fructose transport via PEPPyr PTS  f6p generating ", "bigg_id": "FRUpts2", "segments": {"24": {"to_node_id": "1577053", "from_node_id": "1577052", "b2": null, "b1": null}, "25": {"to_node_id": "1577051", "from_node_id": "1576826", "b2": {"y": 1361.5867919921875, "x": 526.550048828125}, "b1": {"y": 1360.0, "x": 465.0}}, "26": {"to_node_id": "1577051", "from_node_id": "1576819", "b2": {"y": 1360.0, "x": 396.1378949970459}, "b1": {"y": 1452.0322265625, "x": 400.008457770101}}, "27": {"to_node_id": "1576525", "from_node_id": "1577053", "b2": {"y": 1361.586669921875, "x": 917.1118252292455}, "b1": {"y": 1363.1734619140625, "x": 860.370260215258}}, "23": {"to_node_id": "1577052", "from_node_id": "1577051", "b2": null, "b1": null}, "28": {"to_node_id": "1576821", "from_node_id": "1577053", "b2": {"y": 1240.992919921875, "x": 861.106575008484}, "b1": {"y": 1364.76025390625, "x": 861.4990623462952}}}, "genes": [{"bigg_id": "b1819", "name": "manZ"}, {"bigg_id": "b1817", "name": "manX"}, {"bigg_id": "b2415", "name": "ptsH"}, {"bigg_id": "b2416", "name": "ptsI"}, {"bigg_id": "b1818", "name": "manY"}], "reversibility": false, "metabolites": [{"coefficient": -1.0, "bigg_id": "pep_c"}, {"coefficient": 1.0, "bigg_id": "f6p_c"}, {"coefficient": -1.0, "bigg_id": "fru_e"}, {"coefficient": 1.0, "bigg_id": "pyr_c"}], "label_x": 456.41497802734375, "label_y": 1327.7852783203125, "gene_reaction_rule": "b1817 and b1818 and b1819 and b2415 and b2416"}}, "nodes": {"1576509": {"node_is_primary": true, "name": "2-Oxoglutarate", "label_x": 3669.712158203125, "node_type": "metabolite", "y": 3627.0, "x": 3746.0, "bigg_id": "akg_c", "label_y": 3611.942626953125}, "1576508": {"node_is_primary": false, "name": "CO2", "label_x": 3539.820068359375, "node_type": "metabolite", "y": 3710.0, "x": 3620.0, "bigg_id": "co2_c", "label_y": 3711.611572265625}, "1576501": {"node_is_primary": true, "name": "Nicotinamide adenine dinucleotide", "label_x": 3556.820068359375, "node_type": "metabolite", "y": 1147.3958740234375, "x": 3625.7841796875, "bigg_id": "nad_c", "label_y": 1187.06494140625}, "1576500": {"node_is_primary": true, "name": "Nicotinamide adenine dinucleotide phosphate - reduced", "label_x": 3740.0, "node_type": "metabolite", "y": 1270.0, "x": 3740.0, "bigg_id": "nadph_c", "label_y": 1310.0}, "1576503": {"node_is_primary": true, "name": "Fumarate", "label_x": 2867.189453125, "node_type": "metabolite", "y": 2920.0, "x": 2843.0, "bigg_id": "fum_c", "label_y": 2939.602783203125}, "1576502": {"node_is_primary": false, "name": "H2O", "label_x": 2693.4130859375, "node_type": "metabolite", "y": 2921.0, "x": 2715.0, "bigg_id": "h2o_c", "label_y": 2896.71923828125}, "1576505": {"node_is_primary": true, "name": "Isocitrate", "label_x": 3344.32373046875, "node_type": "metabolite", "y": 3976.0, "x": 3413.0, "bigg_id": "icit_c", "label_y": 3949.222900390625}, "1576504": {"node_is_primary": true, "name": "L-Malate", "label_x": 2506.83544921875, "node_type": "metabolite", "y": 3192.0, "x": 2621.0, "bigg_id": "mal__L_c", "label_y": 3174.826416015625}, "1576507": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide phosphate - reduced", "label_x": 3557.6474609375, "node_type": "metabolite", "y": 3660.0, "x": 3659.0, "bigg_id": "nadph_c", "label_y": 3655.388427734375}, "1576506": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide phosphate", "label_x": 3495.0, "node_type": "metabolite", "y": 4065.0, "x": 3495.0, "bigg_id": "nadp_c", "label_y": 4098.0}, "1576992": {"y": 980.0, "x": 2840.0, "node_type": "multimarker"}, "1576868": {"y": 4158.0, "x": 5020.0, "node_type": "midmarker"}, "1576993": {"y": 840.0, "x": 2840.0, "node_type": "midmarker"}, "1576863": {"y": 2880.0, "x": 5025.0, "node_type": "midmarker"}, "1576860": {"y": 1665.0, "x": 835.0, "node_type": "multimarker"}, "1576861": {"y": 1765.0, "x": 835.0, "node_type": "multimarker"}, "1576866": {"y": 1260.0, "x": 4145.0, "node_type": "midmarker"}, "1576867": {"y": 1200.0, "x": 4145.0, "node_type": "multimarker"}, "1576864": {"y": 3766.0, "x": 3417.0, "node_type": "multimarker"}, "1576865": {"y": 3857.0, "x": 3417.0, "node_type": "midmarker"}, "1576490": {"node_is_primary": true, "name": "6-Phospho-D-gluconate", "label_x": 1800.0250244140625, "node_type": "metabolite", "y": 1265.0, "x": 1827.0, "bigg_id": "6pgc_c", "label_y": 1235.0}, "1576996": {"y": 4501.49560546875, "x": 1715.0, "node_type": "multimarker"}, "1576997": {"y": 1008.8675537109375, "x": 1056.5865478515625, "node_type": "midmarker"}, "1576994": {"y": 4745.0, "x": 1715.0, "node_type": "multimarker"}, "1576995": {"y": 4585.0, "x": 1715.0, "node_type": "midmarker"}, "1576615": {"node_is_primary": false, "name": "ATP", "label_x": 4552.7265625, "node_type": "metabolite", "y": 4258.0, "x": 4535.0, "bigg_id": "atp_c", "label_y": 4269.94287109375}, "1576614": {"node_is_primary": false, "name": "Coenzyme A", "label_x": 1835.0, "node_type": "metabolite", "y": 4135.0, "x": 1815.0, "bigg_id": "coa_c", "label_y": 4135.0}, "1576617": {"node_is_primary": false, "name": "Phosphate", "label_x": 4268.884765625, "node_type": "metabolite", "y": 4258.0, "x": 4285.0, "bigg_id": "pi_c", "label_y": 4287.6689453125}, "1576616": {"node_is_primary": false, "name": "H2O", "label_x": 4481.77685546875, "node_type": "metabolite", "y": 4258.0, "x": 4485.0, "bigg_id": "h2o_c", "label_y": 4287.6689453125}, "1576613": {"node_is_primary": true, "name": "Acetyl phosphate", "label_x": 1745.0, "node_type": "metabolite", "y": 4175.0, "x": 1715.0, "bigg_id": "actp_c", "label_y": 4175.0}, "1576612": {"node_is_primary": false, "name": "Phosphate", "label_x": 1835.0, "node_type": "metabolite", "y": 4035.0, "x": 1815.0, "bigg_id": "pi_c", "label_y": 4035.0}, "1576619": {"node_is_primary": false, "name": "H+", "label_x": 4331.77734375, "node_type": "metabolite", "y": 4258.0, "x": 4335.0, "bigg_id": "h_c", "label_y": 4286.0576171875}, "1576618": {"node_is_primary": false, "name": "ADP", "label_x": 4381.77685546875, "node_type": "metabolite", "y": 4258.0, "x": 4385.0, "bigg_id": "adp_c", "label_y": 4290.89208984375}, "1576598": {"node_is_primary": true, "name": "2-Oxoglutarate", "label_x": 4922.0, "node_type": "metabolite", "y": 3228.0, "x": 4922.0, "bigg_id": "akg_e", "label_y": 3268.0}, "1576599": {"node_is_primary": false, "name": "H+", "label_x": 4861.39599609375, "node_type": "metabolite", "y": 3321.0, "x": 4834.0, "bigg_id": "h_e", "label_y": 3334.553955078125}, "1576596": {"node_is_primary": false, "name": "H+", "label_x": 2754.13232421875, "node_type": "metabolite", "y": 4452.0, "x": 2793.0, "bigg_id": "h_c", "label_y": 4426.61181640625}, "1576597": {"node_is_primary": true, "name": "Phosphate", "label_x": 2921.0, "node_type": "metabolite", "y": 4430.0, "x": 2880.0, "bigg_id": "pi_c", "label_y": 4428.0}, "1576594": {"node_is_primary": true, "name": "Phosphate", "label_x": 2910.0, "node_type": "metabolite", "y": 4839.0, "x": 2880.0, "bigg_id": "pi_e", "label_y": 4839.0}, "1576595": {"node_is_primary": false, "name": "H+", "label_x": 2733.83544921875, "node_type": "metabolite", "y": 4778.0, "x": 2793.0, "bigg_id": "h_e", "label_y": 4763.8515625}, "1576592": {"node_is_primary": false, "name": "ADP", "label_x": 1285.0, "node_type": "metabolite", "y": 3545.0, "x": 1285.0, "bigg_id": "adp_c", "label_y": 3575.0}, "1576593": {"node_is_primary": false, "name": "CO2", "label_x": 1215.0, "node_type": "metabolite", "y": 3515.0, "x": 1215.0, "bigg_id": "co2_c", "label_y": 3535.0}, "1576590": {"node_is_primary": true, "name": "Formate", "label_x": 1495.230712890625, "node_type": "metabolite", "y": 4095.0, "x": 1460.0, "bigg_id": "for_c", "label_y": 4083.958984375}, "1576591": {"node_is_primary": false, "name": "ATP", "label_x": 1525.0, "node_type": "metabolite", "y": 3625.0, "x": 1505.0, "bigg_id": "atp_c", "label_y": 3625.0}, "1576819": {"node_is_primary": false, "name": "Phosphoenolpyruvate", "label_x": 554.497314453125, "node_type": "metabolite", "y": 1448.4132080078125, "x": 565.6046142578125, "bigg_id": "pep_c", "label_y": 1479.5206298828125}, "1576817": {"node_is_primary": true, "name": "Acetaldehyde", "label_x": 2210.0, "node_type": "metabolite", "y": 3945.0, "x": 2210.0, "bigg_id": "acald_c", "label_y": 3905.0}, "1576816": {"node_is_primary": true, "name": "L-Malate", "label_x": 2640.0, "node_type": "metabolite", "y": 650.0, "x": 2610.0, "bigg_id": "mal__L_e", "label_y": 630.0}, "1576815": {"node_is_primary": true, "name": "Acetaldehyde", "label_x": 2240.0, "node_type": "metabolite", "y": 4837.65283203125, "x": 2210.0, "bigg_id": "acald_e", "label_y": 4837.65283203125}, "1576814": {"node_is_primary": false, "name": "Ubiquinone-8", "label_x": 3228.082275390625, "node_type": "metabolite", "y": 2730.0, "x": 3210.0, "bigg_id": "q8_c", "label_y": 2736.34716796875}, "1576813": {"node_is_primary": false, "name": "H+", "label_x": 2406.0, "node_type": "metabolite", "y": 3980.0, "x": 2392.0, "bigg_id": "h_c", "label_y": 3965.0}, "1576812": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide - reduced", "label_x": 1868.892578125, "node_type": "metabolite", "y": 3860.0, "x": 1890.0, "bigg_id": "nadh_c", "label_y": 3840.810302734375}, "1576811": {"node_is_primary": false, "name": "H+", "label_x": 1245.23974609375, "node_type": "metabolite", "y": 4440.0, "x": 1270.0, "bigg_id": "h_c", "label_y": 4424.13232421875}, "1576810": {"node_is_primary": false, "name": "H+", "label_x": 2473.50439453125, "node_type": "metabolite", "y": 1010.0, "x": 2510.0, "bigg_id": "h_c", "label_y": 1043.1734619140625}, "1576692": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide phosphate - reduced", "label_x": 2220.0, "node_type": "metabolite", "y": 3540.0, "x": 2200.0, "bigg_id": "nadph_c", "label_y": 3550.0}, "1577106": {"y": 4020.0757924471372, "x": 3331.3033751186185, "node_type": "multimarker"}, "1577104": {"y": 4035.7165277261324, "x": 3294.488060371458, "node_type": "multimarker"}, "1577105": {"y": 4027.896160086635, "x": 3312.895717745038, "node_type": "midmarker"}, "1577069": {"y": 4506.7353515625, "x": 1053.4132080078125, "node_type": "multimarker"}, "1577068": {"y": 4583.8583984375, "x": 1055.0, "node_type": "midmarker"}, "1577100": {"y": 4030.8645761345497, "x": 3074.275683525833, "node_type": "midmarker"}, "1577101": {"y": 4038.0833974815746, "x": 3092.9274560517806, "node_type": "multimarker"}, "1577065": {"y": 2819.0, "x": 3129.0, "node_type": "midmarker"}, "1577064": {"y": 2817.0, "x": 3180.0, "node_type": "multimarker"}, "1577067": {"y": 4660.98193359375, "x": 1055.0, "node_type": "multimarker"}, "1577066": {"y": 2826.0, "x": 3078.0, "node_type": "multimarker"}, "1577061": {"y": 2570.0, "x": 4630.0, "node_type": "multimarker"}, "1577063": {"y": 2570.0, "x": 4710.0, "node_type": "multimarker"}, "1577062": {"y": 2570.0, "x": 4670.0, "node_type": "midmarker"}, "1576884": {"y": 3945.0, "x": 155.0, "node_type": "midmarker"}, "1576885": {"y": 1415.0, "x": 2045.0, "node_type": "midmarker"}, "1576929": {"y": 1900.0, "x": 4690.0, "node_type": "multimarker"}, "1576887": {"y": 2230.0, "x": 4986.0, "node_type": "midmarker"}, "1576880": {"y": 3635.0, "x": 4779.0, "node_type": "multimarker"}, "1576881": {"y": 4925.0, "x": 1055.0, "node_type": "midmarker"}, "1576923": {"y": 3228.0, "x": 4792.0, "node_type": "multimarker"}, "1576922": {"y": 3228.0, "x": 4502.0, "node_type": "multimarker"}, "1576921": {"y": 4725.0, "x": 2880.0, "node_type": "multimarker"}, "1576920": {"y": 4580.0, "x": 2880.0, "node_type": "midmarker"}, "1576927": {"y": 2195.0, "x": 955.0, "node_type": "midmarker"}, "1576926": {"y": 1995.0, "x": 1055.0, "node_type": "midmarker"}, "1576925": {"y": 2045.0, "x": 1055.0, "node_type": "multimarker"}, "1576924": {"y": 3228.0, "x": 4662.0, "node_type": "midmarker"}, "1576491": {"node_is_primary": false, "name": "CO2", "label_x": 2007.0, "node_type": "metabolite", "y": 1165.0, "x": 2007.0, "bigg_id": "co2_c", "label_y": 1145.0}, "1577087": {"node_is_primary": false, "name": "Coenzyme A", "label_x": 5175.48828125, "node_type": "metabolite", "y": 4931.947265625, "x": 5208.85205078125, "bigg_id": "coa_c", "label_y": 4975.3330078125}, "1577086": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide", "label_x": 4860.95166015625, "node_type": "metabolite", "y": 4529.25048828125, "x": 4893.27099609375, "bigg_id": "nad_c", "label_y": 4501.22509765625}, "1577085": {"node_is_primary": false, "name": "Pyruvate", "label_x": 4962.07666015625, "node_type": "metabolite", "y": 4509.18115234375, "x": 4988.05859375, "bigg_id": "pyr_c", "label_y": 4488.5498046875}, "1577084": {"node_is_primary": false, "name": "D-Fructose 6-phosphate", "label_x": 5052.6396484375, "node_type": "metabolite", "y": 4498.61865234375, "x": 5087.0712890625, "bigg_id": "f6p_c", "label_y": 4477.9873046875}, "1577083": {"node_is_primary": false, "name": "ATP", "label_x": 5152.708984375, "node_type": "metabolite", "y": 4488.05615234375, "x": 5183.9716796875, "bigg_id": "atp_c", "label_y": 4461.08740234375}, "1577082": {"node_is_primary": false, "name": "Alpha-D-Ribose 5-phosphate", "label_x": 5390.7685546875, "node_type": "metabolite", "y": 4418.7158203125, "x": 5403.0185546875, "bigg_id": "r5p_c", "label_y": 4391.7470703125}, "1577081": {"node_is_primary": false, "name": "H+", "label_x": 5204.56640625, "node_type": "metabolite", "y": 4994.3544921875, "x": 5262.95361328125, "bigg_id": "h_c", "label_y": 5025.4677734375}, "1577080": {"node_is_primary": false, "name": "D-Erythrose 4-phosphate", "label_x": 5442.19677734375, "node_type": "metabolite", "y": 4466.33544921875, "x": 5437.546875, "bigg_id": "e4p_c", "label_y": 4450.9853515625}, "1576851": {"y": 3945.0, "x": 1555.0, "node_type": "multimarker"}, "1577089": {"node_is_primary": false, "name": "D-Glucose 6-phosphate", "label_x": 4679.8271484375, "node_type": "metabolite", "y": 4559.88134765625, "x": 4700.52734375, "bigg_id": "g6p_c", "label_y": 4537.1376953125}, "1577088": {"node_is_primary": false, "name": "Oxaloacetate", "label_x": 4770.38916015625, "node_type": "metabolite", "y": 4544.03759765625, "x": 4783.69580078125, "bigg_id": "oaa_c", "label_y": 4522.349609375}, "1576850": {"y": 3945.0, "x": 1495.0, "node_type": "midmarker"}, "1576853": {"y": 3519.0, "x": 1493.0, "node_type": "multimarker"}, "1576852": {"y": 3486.0, "x": 1414.0, "node_type": "midmarker"}, "1576998": {"y": 976.1735229492188, "x": 1057.0, "node_type": "multimarker"}, "1576498": {"node_is_primary": false, "name": "H+", "label_x": 3529.338134765625, "node_type": "metabolite", "y": 650.0, "x": 3510.0, "bigg_id": "h_e", "label_y": 639.6690673828125}, "1576857": {"y": 1395.0, "x": 1055.0, "node_type": "midmarker"}, "1576856": {"y": 3225.0, "x": 1055.0, "node_type": "midmarker"}, "1576855": {"y": 3265.0, "x": 1055.0, "node_type": "multimarker"}, "1576854": {"y": 3458.0, "x": 1348.0, "node_type": "multimarker"}, "1576493": {"node_is_primary": true, "name": "D-Ribulose 5-phosphate", "label_x": 2155.0, "node_type": "metabolite", "y": 1265.0, "x": 2155.0, "bigg_id": "ru5p__D_c", "label_y": 1235.0}, "1576492": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide phosphate - reduced", "label_x": 2080.0, "node_type": "metabolite", "y": 1165.0, "x": 2057.0, "bigg_id": "nadph_c", "label_y": 1140.0}, "1576859": {"y": 1715.0, "x": 835.0, "node_type": "midmarker"}, "1576858": {"y": 4598.0, "x": 3989.0, "node_type": "midmarker"}, "1576497": {"node_is_primary": true, "name": "Nicotinamide adenine dinucleotide - reduced", "label_x": 3450.0, "node_type": "metabolite", "y": 1120.0, "x": 3420.0, "bigg_id": "nadh_c", "label_y": 1150.0}, "1576496": {"node_is_primary": true, "name": "Nicotinamide adenine dinucleotide phosphate", "label_x": 3330.0, "node_type": "metabolite", "y": 1270.0, "x": 3330.0, "bigg_id": "nadp_c", "label_y": 1310.0}, "1576495": {"node_is_primary": true, "name": "O2", "label_x": 4259.09326171875, "node_type": "metabolite", "y": 1660.0, "x": 4330.0, "bigg_id": "o2_c", "label_y": 1677.4388427734375}, "1576494": {"node_is_primary": true, "name": "O2", "label_x": 4840.3310546875, "node_type": "metabolite", "y": 1660.0, "x": 4850.0, "bigg_id": "o2_e", "label_y": 1702.89208984375}, "1576549": {"node_is_primary": false, "name": "H+", "label_x": 911.677978515625, "node_type": "metabolite", "y": 3625.0, "x": 965.0, "bigg_id": "h_c", "label_y": 3612.305908203125}, "1576548": {"node_is_primary": true, "name": "D-Fructose 6-phosphate", "label_x": 2367.636962890625, "node_type": "metabolite", "y": 2186.826416015625, "x": 2362.636962890625, "bigg_id": "f6p_c", "label_y": 2216.826416015625}, "1576545": {"node_is_primary": true, "name": "Glyceraldehyde 3-phosphate", "label_x": 2375.091552734375, "node_type": "metabolite", "y": 1865.0, "x": 2358.984130859375, "bigg_id": "g3p_c", "label_y": 1898.4132080078125}, "1576544": {"node_is_primary": true, "name": "CO2", "label_x": 3651.0, "node_type": "metabolite", "y": 4754.0, "x": 3621.0, "bigg_id": "co2_e", "label_y": 4754.0}, "1576547": {"node_is_primary": true, "name": "D-Erythrose 4-phosphate", "label_x": 1922.7852783203125, "node_type": "metabolite", "y": 2190.0, "x": 1945.0, "bigg_id": "e4p_c", "label_y": 2242.214599609375}, "1576546": {"node_is_primary": true, "name": "Sedoheptulose 7-phosphate", "label_x": 1955.8675537109375, "node_type": "metabolite", "y": 1865.0, "x": 1983.082275390625, "bigg_id": "s7p_c", "label_y": 1814.314697265625}, "1576542": {"node_is_primary": true, "name": "Ubiquinol-8", "label_x": 4411.00048828125, "node_type": "metabolite", "y": 2210.3310546875, "x": 4508.47509765625, "bigg_id": "q8h2_c", "label_y": 2217.395751953125}, "1577102": {"node_is_primary": false, "name": "H2O", "label_x": 3189.1795476587818, "node_type": "metabolite", "y": 3976.144484067998, "x": 3188.1170476587818, "bigg_id": "h2o_c", "label_y": 3930.712355161748}, "1576648": {"node_is_primary": false, "name": "H+", "label_x": 2620.0, "node_type": "metabolite", "y": 4760.0, "x": 2600.0, "bigg_id": "h_e", "label_y": 4760.0}, "1576649": {"node_is_primary": true, "name": "Ethanol", "label_x": 2530.0, "node_type": "metabolite", "y": 4830.0, "x": 2500.0, "bigg_id": "etoh_e", "label_y": 4830.0}, "1576646": {"node_is_primary": false, "name": "Phosphate", "label_x": 684.8515014648438, "node_type": "metabolite", "y": 3425.0, "x": 735.0, "bigg_id": "pi_c", "label_y": 3409.13232421875}, "1576647": {"node_is_primary": true, "name": "D-Glucose", "label_x": 1085.066162109375, "node_type": "metabolite", "y": 705.0, "x": 1055.066162109375, "bigg_id": "glc__D_e", "label_y": 705.0}, "1576644": {"node_is_primary": false, "name": "H+", "label_x": 672.1574096679688, "node_type": "metabolite", "y": 3475.0, "x": 735.0, "bigg_id": "h_c", "label_y": 3478.173583984375}, "1576645": {"node_is_primary": false, "name": "AMP", "label_x": 640.4221801757812, "node_type": "metabolite", "y": 3525.0, "x": 735.0, "bigg_id": "amp_c", "label_y": 3545.6279296875}, "1576642": {"node_is_primary": false, "name": "ATP", "label_x": 670.5706176757812, "node_type": "metabolite", "y": 3855.0, "x": 735.0, "bigg_id": "atp_c", "label_y": 3840.71923828125}, "1576643": {"node_is_primary": false, "name": "H2O", "label_x": 681.677978515625, "node_type": "metabolite", "y": 3805.0, "x": 735.0, "bigg_id": "h2o_c", "label_y": 3787.545654296875}, "1576640": {"node_is_primary": true, "name": "H2O", "label_x": 3287.0, "node_type": "metabolite", "y": 4434.0, "x": 3257.0, "bigg_id": "h2o_c", "label_y": 4434.0}, "1576641": {"node_is_primary": true, "name": "CO2", "label_x": 3651.0, "node_type": "metabolite", "y": 4434.0, "x": 3621.0, "bigg_id": "co2_c", "label_y": 4434.0}, "1577103": {"node_is_primary": true, "name": "Cis-Aconitate", "label_x": 3156.1556150985407, "node_type": "metabolite", "y": 4053.2845721909744, "x": 3197.4642088485407, "bigg_id": "acon_C_c", "label_y": 4098.026271409724}, "1576991": {"y": 730.0, "x": 2840.0, "node_type": "multimarker"}, "1577034": {"y": 4570.0, "x": 2210.0, "node_type": "midmarker"}, "1577035": {"y": 4944.0, "x": 2211.0, "node_type": "midmarker"}, "1577032": {"y": 3945.0, "x": 2010.0, "node_type": "midmarker"}, "1577033": {"y": 3945.0, "x": 1980.0, "node_type": "multimarker"}, "1577030": {"y": 4925.0, "x": 1460.0, "node_type": "midmarker"}, "1577031": {"y": 3945.0, "x": 2040.0, "node_type": "multimarker"}, "1576974": {"y": 543.4132690429688, "x": 1056.6529541015625, "node_type": "midmarker"}, "1576975": {"y": 4430.0, "x": 2500.0, "node_type": "multimarker"}, "1576976": {"y": 4550.0, "x": 2500.0, "node_type": "midmarker"}, "1576977": {"y": 4730.0, "x": 2500.0, "node_type": "multimarker"}, "1576970": {"y": 3805.0, "x": 835.0, "node_type": "multimarker"}, "1576971": {"y": 3525.0, "x": 835.0, "node_type": "multimarker"}, "1576972": {"y": 3645.0, "x": 835.0, "node_type": "midmarker"}, "1576978": {"y": 2995.0, "x": 1055.0, "node_type": "midmarker"}, "1576989": {"y": 4925.107421875, "x": 2880.0, "node_type": "midmarker"}, "1576602": {"node_is_primary": false, "name": "H+", "label_x": 4234.01416015625, "node_type": "metabolite", "y": 1895.1654052734375, "x": 4301.69775390625, "bigg_id": "h_c", "label_y": 1903.8848876953125}, "1576603": {"node_is_primary": false, "name": "H+", "label_x": 4858.38818359375, "node_type": "metabolite", "y": 1900.0, "x": 4860.0, "bigg_id": "h_e", "label_y": 1950.6187744140625}, "1576600": {"node_is_primary": false, "name": "H+", "label_x": 4490.337890625, "node_type": "metabolite", "y": 3328.0, "x": 4472.0, "bigg_id": "h_c", "label_y": 3342.330810546875}, "1576601": {"node_is_primary": true, "name": "Dihydroxyacetone phosphate", "label_x": 739.3148193359375, "node_type": "metabolite", "y": 2195.0, "x": 855.0, "bigg_id": "dhap_c", "label_y": 2179.132568359375}, "1576606": {"node_is_primary": false, "name": "Acetyl-CoA", "label_x": 3125.0, "node_type": "metabolite", "y": 3402.0, "x": 3105.0, "bigg_id": "accoa_c", "label_y": 3402.0}, "1576607": {"node_is_primary": false, "name": "H2O", "label_x": 3190.0, "node_type": "metabolite", "y": 3480.0, "x": 3170.0, "bigg_id": "h2o_c", "label_y": 3480.0}, "1576604": {"node_is_primary": false, "name": "H2O", "label_x": 4452.77001953125, "node_type": "metabolite", "y": 1760.9495849609375, "x": 4439.09375, "bigg_id": "h2o_c", "label_y": 1736.77685546875}, "1576605": {"node_is_primary": true, "name": "Alpha-D-Ribose 5-phosphate", "label_x": 2418.413330078125, "node_type": "metabolite", "y": 1555.0, "x": 2419.0, "bigg_id": "r5p_c", "label_y": 1601.1072998046875}, "1576608": {"node_is_primary": false, "name": "H+", "label_x": 2891.0, "node_type": "metabolite", "y": 3220.0, "x": 2871.0, "bigg_id": "h_c", "label_y": 3220.0}, "1576609": {"node_is_primary": false, "name": "Coenzyme A", "label_x": 2800.0, "node_type": "metabolite", "y": 3168.0, "x": 2780.0, "bigg_id": "coa_c", "label_y": 3168.0}, "1576808": {"node_is_primary": false, "name": "H+", "label_x": 4874.1728515625, "node_type": "metabolite", "y": 2570.0, "x": 4850.0, "bigg_id": "h_e", "label_y": 2601.280517578125}, "1576809": {"node_is_primary": true, "name": "Nicotinamide adenine dinucleotide", "label_x": 4356.72412109375, "node_type": "metabolite", "y": 2646.77685546875, "x": 4449.00732421875, "bigg_id": "nad_c", "label_y": 2646.95849609375}, "1576516": {"node_is_primary": false, "name": "H2O", "label_x": 1315.0, "node_type": "metabolite", "y": 3375.0, "x": 1295.0, "bigg_id": "h2o_c", "label_y": 3375.0}, "1576517": {"node_is_primary": true, "name": "Phosphoenolpyruvate", "label_x": 1085.0, "node_type": "metabolite", "y": 3375.0, "x": 1055.0, "bigg_id": "pep_c", "label_y": 3355.0}, "1576514": {"node_is_primary": true, "name": "Acetyl-CoA", "label_x": 1695.0, "node_type": "metabolite", "y": 3945.0, "x": 1715.0, "bigg_id": "accoa_c", "label_y": 3965.0}, "1576515": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide - reduced", "label_x": 1647.545654296875, "node_type": "metabolite", "y": 3885.0, "x": 1655.0, "bigg_id": "nadh_c", "label_y": 3855.4794921875}, "1576512": {"node_is_primary": false, "name": "Coenzyme A", "label_x": 1287.066162109375, "node_type": "metabolite", "y": 3905.0, "x": 1315.0, "bigg_id": "coa_c", "label_y": 3887.545654296875}, "1576513": {"node_is_primary": false, "name": "CO2", "label_x": 1595.0, "node_type": "metabolite", "y": 3855.0, "x": 1605.0, "bigg_id": "co2_c", "label_y": 3835.0}, "1576510": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide", "label_x": 1394.189697265625, "node_type": "metabolite", "y": 3855.0, "x": 1365.0, "bigg_id": "nad_c", "label_y": 3851.826416015625}, "1576511": {"node_is_primary": true, "name": "Pyruvate", "label_x": 1025.0, "node_type": "metabolite", "y": 3945.0, "x": 1055.0, "bigg_id": "pyr_c", "label_y": 3965.0}, "1576982": {"y": 4275.0, "x": 1715.0, "node_type": "midmarker"}, "1576691": {"node_is_primary": false, "name": "CO2", "label_x": 2280.0, "node_type": "metabolite", "y": 3510.0, "x": 2260.0, "bigg_id": "co2_c", "label_y": 3510.0}, "1576690": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide phosphate", "label_x": 2450.0, "node_type": "metabolite", "y": 3370.0, "x": 2430.0, "bigg_id": "nadp_c", "label_y": 3370.0}, "1576518": {"node_is_primary": false, "name": "CO2", "label_x": 1215.0, "node_type": "metabolite", "y": 3345.0, "x": 1205.0, "bigg_id": "co2_c", "label_y": 3325.0}, "1576519": {"node_is_primary": false, "name": "H+", "label_x": 1635.0, "node_type": "metabolite", "y": 3475.0, "x": 1615.0, "bigg_id": "h_c", "label_y": 3475.0}, "1577078": {"node_is_primary": false, "name": "L-Glutamate", "label_x": 5555.015625, "node_type": "metabolite", "y": 4651.92236328125, "x": 5534.521484375, "bigg_id": "glu__L_c", "label_y": 4645.02197265625}, "1577079": {"node_is_primary": false, "name": "Glyceraldehyde 3-phosphate", "label_x": 5534.87109375, "node_type": "metabolite", "y": 4517.58447265625, "x": 5512.26513671875, "bigg_id": "g3p_c", "label_y": 4508.57177734375}, "1577072": {"node_is_primary": false, "name": "H+", "label_x": 1123.4132080078125, "node_type": "metabolite", "y": 4416.7353515625, "x": 1093.4132080078125, "bigg_id": "h_c", "label_y": 4426.7353515625}, "1577073": {"node_is_primary": false, "name": "H2O", "label_x": 5539.50146484375, "node_type": "metabolite", "y": 4574.02490234375, "x": 5527.4580078125, "bigg_id": "h2o_c", "label_y": 4562.89990234375}, "1577071": {"node_is_primary": false, "name": "H+", "label_x": 1125.0, "node_type": "metabolite", "y": 4750.98193359375, "x": 1095.0, "bigg_id": "h_e", "label_y": 4760.98193359375}, "1577076": {"y": 4757.48193359375, "x": 5334.0517578125, "node_type": "multimarker"}, "1577077": {"node_is_primary": false, "name": "ADP", "label_x": 5529.1103515625, "node_type": "metabolite", "y": 4924.5068359375, "x": 5503.33544921875, "bigg_id": "adp_c", "label_y": 4931.337890625}, "1577074": {"y": 4717.48193359375, "x": 5334.0517578125, "node_type": "multimarker"}, "1577075": {"y": 4737.48193359375, "x": 5334.0517578125, "node_type": "midmarker"}, "1576677": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide phosphate - reduced", "label_x": 3935.431640625, "node_type": "metabolite", "y": 3558.0, "x": 3992.0, "bigg_id": "nadph_c", "label_y": 3532.22314453125}, "1576676": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide phosphate", "label_x": 4142.0, "node_type": "metabolite", "y": 3558.0, "x": 4142.0, "bigg_id": "nadp_c", "label_y": 3528.0}, "1576675": {"node_is_primary": false, "name": "H2O", "label_x": 4210.0, "node_type": "metabolite", "y": 3558.0, "x": 4192.0, "bigg_id": "h2o_c", "label_y": 3530.0}, "1576674": {"node_is_primary": false, "name": "H+", "label_x": 4456.0, "node_type": "metabolite", "y": 3087.0, "x": 4456.0, "bigg_id": "h_c", "label_y": 3109.0}, "1576673": {"node_is_primary": false, "name": "H+", "label_x": 4836.0, "node_type": "metabolite", "y": 3087.0, "x": 4836.0, "bigg_id": "h_e", "label_y": 3115.0}, "1576672": {"node_is_primary": false, "name": "H+", "label_x": 1169.0, "node_type": "metabolite", "y": 2465.0, "x": 1145.0, "bigg_id": "h_c", "label_y": 2465.0}, "1576671": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide - reduced", "label_x": 1165.0, "node_type": "metabolite", "y": 2515.0, "x": 1145.0, "bigg_id": "nadh_c", "label_y": 2515.0}, "1576670": {"node_is_primary": false, "name": "Phosphate", "label_x": 1165.0, "node_type": "metabolite", "y": 2315.0, "x": 1145.0, "bigg_id": "pi_c", "label_y": 2315.0}, "1576679": {"node_is_primary": false, "name": "H+", "label_x": 4050.0, "node_type": "metabolite", "y": 3558.0, "x": 4042.0, "bigg_id": "h_c", "label_y": 3530.0}, "1576678": {"node_is_primary": false, "name": "Ammonium", "label_x": 3856.820068359375, "node_type": "metabolite", "y": 3558.0, "x": 3942.0, "bigg_id": "nh4_c", "label_y": 3573.222900390625}, "1576938": {"y": 4158.0, "x": 4415.0, "node_type": "multimarker"}, "1576939": {"y": 4158.0, "x": 4435.0, "node_type": "midmarker"}, "1576930": {"y": 1900.0, "x": 4630.0, "node_type": "multimarker"}, "1576931": {"y": 1425.0, "x": 2305.0, "node_type": "midmarker"}, "1576932": {"y": 3341.0, "x": 2843.0, "node_type": "multimarker"}, "1576933": {"y": 3445.0, "x": 2994.0, "node_type": "multimarker"}, "1576934": {"y": 3388.0, "x": 2911.0, "node_type": "midmarker"}, "1576935": {"y": 4065.0, "x": 1715.0, "node_type": "multimarker"}, "1576936": {"y": 4105.0, "x": 1715.0, "node_type": "multimarker"}, "1576937": {"y": 4085.0, "x": 1715.0, "node_type": "midmarker"}, "1577009": {"y": 470.0, "x": 2840.0, "node_type": "midmarker"}, "1577008": {"y": 2395.0, "x": 1055.0, "node_type": "midmarker"}, "1577007": {"y": 2435.0, "x": 1055.0, "node_type": "multimarker"}, "1577006": {"y": 2345.0, "x": 1055.0, "node_type": "multimarker"}, "1577005": {"y": 1265.0, "x": 1617.0, "node_type": "multimarker"}, "1577004": {"y": 1265.0, "x": 1657.0, "node_type": "multimarker"}, "1577003": {"y": 1265.0, "x": 1637.0, "node_type": "midmarker"}, "1577002": {"y": 2846.0, "x": 4560.0, "node_type": "multimarker"}, "1577001": {"y": 2846.0, "x": 4770.0, "node_type": "multimarker"}, "1577000": {"y": 2846.0, "x": 4667.0, "node_type": "midmarker"}, "1577094": {"node_is_primary": false, "name": "Phosphoenolpyruvate", "label_x": 4379.6201171875, "node_type": "metabolite", "y": 4629.59423828125, "x": 4414.0517578125, "bigg_id": "pep_c", "label_y": 4607.90673828125}, "1577095": {"node_is_primary": false, "name": "L-Glutamine", "label_x": 4253.14453125, "node_type": "metabolite", "y": 4650.7197265625, "x": 4332.9951171875, "bigg_id": "gln__L_c", "label_y": 4627.97607421875}, "1577096": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide phosphate", "label_x": 4968.08447265625, "node_type": "metabolite", "y": 4864.818359375, "x": 5028.71435546875, "bigg_id": "nadp_c", "label_y": 4902.36181640625}, "1577097": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide phosphate - reduced", "label_x": 4203.775390625, "node_type": "metabolite", "y": 4682.4072265625, "x": 4267.78271484375, "bigg_id": "nadph_c", "label_y": 4664.94482421875}, "1577090": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide - reduced", "label_x": 5078.88623046875, "node_type": "metabolite", "y": 4897.1259765625, "x": 5134.0517578125, "bigg_id": "nadh_c", "label_y": 4936.322265625}, "1577091": {"node_is_primary": false, "name": "2-Oxoglutarate", "label_x": 5497.31591796875, "node_type": "metabolite", "y": 4979.51025390625, "x": 5481.046875, "bigg_id": "akg_c", "label_y": 5004.2978515625}, "1577092": {"node_is_primary": false, "name": "Acetyl-CoA", "label_x": 4556.52001953125, "node_type": "metabolite", "y": 4576.78173828125, "x": 4601.51416015625, "bigg_id": "accoa_c", "label_y": 4549.81298828125}, "1577093": {"node_is_primary": false, "name": "3-Phospho-D-glycerate", "label_x": 4459.6201171875, "node_type": "metabolite", "y": 4602.1318359375, "x": 4508.83935546875, "bigg_id": "3pg_c", "label_y": 4576.21923828125}, "1577098": {"node_is_primary": false, "name": "Phosphate", "label_x": 4884.8583984375, "node_type": "metabolite", "y": 4831.37548828125, "x": 4933.43505859375, "bigg_id": "pi_c", "label_y": 4859.1142578125}, "1577099": {"y": 4023.6457547875243, "x": 3055.6239109998846, "node_type": "multimarker"}, "1576529": {"node_is_primary": true, "name": "D-Fructose 1,6-bisphosphate", "label_x": 1096.404296875, "node_type": "metabolite", "y": 1925.0, "x": 1055.0, "bigg_id": "fdp_c", "label_y": 1928.173583984375}, "1576528": {"node_is_primary": false, "name": "H2O", "label_x": 672.9427490234375, "node_type": "metabolite", "y": 1855.0, "x": 765.0, "bigg_id": "h2o_c", "label_y": 1861.3470458984375}, "1576527": {"node_is_primary": true, "name": "Ammonium", "label_x": 4019.0, "node_type": "metabolite", "y": 4441.0, "x": 3989.0, "bigg_id": "nh4_c", "label_y": 4441.0}, "1576526": {"node_is_primary": true, "name": "Ammonium", "label_x": 4019.0, "node_type": "metabolite", "y": 4757.0, "x": 3989.0, "bigg_id": "nh4_e", "label_y": 4757.0}, "1576525": {"node_is_primary": true, "name": "D-Fructose 6-phosphate", "label_x": 1075.0, "node_type": "metabolite", "y": 1545.0, "x": 1055.0, "bigg_id": "f6p_c", "label_y": 1525.0}, "1576524": {"node_is_primary": true, "name": "D-Glucose 6-phosphate", "label_x": 1075.0, "node_type": "metabolite", "y": 1265.0, "x": 1055.0, "bigg_id": "g6p_c", "label_y": 1245.0}, "1576523": {"node_is_primary": false, "name": "H2O", "label_x": 886.289794921875, "node_type": "metabolite", "y": 3325.0, "x": 965.0, "bigg_id": "h2o_c", "label_y": 3307.958740234375}, "1576522": {"node_is_primary": true, "name": "D-Glycerate 2-phosphate", "label_x": 1093.0, "node_type": "metabolite", "y": 3125.0, "x": 1055.0, "bigg_id": "2pg_c", "label_y": 3125.0}, "1576521": {"node_is_primary": true, "name": "Oxaloacetate", "label_x": 2692.0, "node_type": "metabolite", "y": 3724.0, "x": 2659.0, "bigg_id": "oaa_c", "label_y": 3724.0}, "1576520": {"node_is_primary": false, "name": "Phosphate", "label_x": 1685.0, "node_type": "metabolite", "y": 3515.0, "x": 1665.0, "bigg_id": "pi_c", "label_y": 3515.0}, "1576488": {"node_is_primary": false, "name": "ADP", "label_x": 1165.0, "node_type": "metabolite", "y": 2635.0, "x": 1145.0, "bigg_id": "adp_c", "label_y": 2635.0}, "1576841": {"y": 820.0, "x": 3510.0, "node_type": "midmarker"}, "1576842": {"y": 800.0, "x": 3510.0, "node_type": "multimarker"}, "1576843": {"y": 870.0, "x": 3510.0, "node_type": "multimarker"}, "1576844": {"y": 3022.0, "x": 2727.0, "node_type": "multimarker"}, "1576845": {"y": 3076.0, "x": 2684.0, "node_type": "midmarker"}, "1576846": {"y": 3846.0, "x": 3606.0, "node_type": "midmarker"}, "1576847": {"y": 3923.0, "x": 3512.0, "node_type": "multimarker"}, "1576848": {"y": 3781.0, "x": 3663.0, "node_type": "multimarker"}, "1576849": {"y": 3945.0, "x": 1430.0, "node_type": "multimarker"}, "1576485": {"node_is_primary": false, "name": "ATP", "label_x": 1165.0, "node_type": "metabolite", "y": 2805.0, "x": 1145.0, "bigg_id": "atp_c", "label_y": 2805.0}, "1576486": {"node_is_primary": true, "name": "3-Phospho-D-glycerate", "label_x": 1085.0, "node_type": "metabolite", "y": 2875.0, "x": 1055.0, "bigg_id": "3pg_c", "label_y": 2875.0}, "1576487": {"node_is_primary": true, "name": "3-Phospho-D-glyceroyl phosphate", "label_x": 1085.0, "node_type": "metabolite", "y": 2565.0, "x": 1055.0, "bigg_id": "13dpg_c", "label_y": 2565.0}, "1576558": {"node_is_primary": true, "name": "D-Xylulose 5-phosphate", "label_x": 1944.76025390625, "node_type": "metabolite", "y": 1555.0, "x": 1945.0, "bigg_id": "xu5p__D_c", "label_y": 1599.5205078125}, "1576559": {"node_is_primary": true, "name": "H+", "label_x": 4867.7265625, "node_type": "metabolite", "y": 2229.0, "x": 4850.0, "bigg_id": "h_e", "label_y": 2273.503662109375}, "1576552": {"node_is_primary": true, "name": "L-Glutamate", "label_x": 4883.0, "node_type": "metabolite", "y": 3634.0, "x": 4883.0, "bigg_id": "glu__L_e", "label_y": 3604.0}, "1576553": {"node_is_primary": false, "name": "H+", "label_x": 4857.23046875, "node_type": "metabolite", "y": 3703.0, "x": 4825.0, "bigg_id": "h_e", "label_y": 3723.0}, "1576550": {"node_is_primary": false, "name": "ADP", "label_x": 903.744140625, "node_type": "metabolite", "y": 3555.0, "x": 965.0, "bigg_id": "adp_c", "label_y": 3528.02490234375}, "1576551": {"node_is_primary": false, "name": "ATP", "label_x": 929.1323852539062, "node_type": "metabolite", "y": 3815.0, "x": 965.0, "bigg_id": "atp_c", "label_y": 3794.372314453125}, "1576556": {"node_is_primary": true, "name": "D-Lactate", "label_x": 1088.470458984375, "node_type": "metabolite", "y": 4835.0, "x": 1055.0, "bigg_id": "lac__D_e", "label_y": 4857.21484375}, "1576557": {"node_is_primary": true, "name": "Pyruvate", "label_x": 249.61181640625, "node_type": "metabolite", "y": 3945.0, "x": 275.0, "bigg_id": "pyr_e", "label_y": 3994.041015625}, "1576554": {"node_is_primary": true, "name": "L-Glutamate", "label_x": 4221.2158203125, "node_type": "metabolite", "y": 3632.0, "x": 4248.0, "bigg_id": "glu__L_c", "label_y": 3601.0}, "1576555": {"node_is_primary": false, "name": "H+", "label_x": 4503.1796875, "node_type": "metabolite", "y": 3688.0, "x": 4478.0, "bigg_id": "h_c", "label_y": 3696.834716796875}, "1576639": {"node_is_primary": true, "name": "H2O", "label_x": 3287.0, "node_type": "metabolite", "y": 4754.0, "x": 3257.0, "bigg_id": "h2o_e", "label_y": 4754.0}, "1576638": {"node_is_primary": false, "name": "H+", "label_x": 2692.0, "node_type": "metabolite", "y": 3510.0, "x": 2660.0, "bigg_id": "h_c", "label_y": 3510.0}, "1576633": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide", "label_x": 935.0, "node_type": "metabolite", "y": 4255.0, "x": 955.0, "bigg_id": "nad_c", "label_y": 4255.0}, "1576632": {"node_is_primary": false, "name": "H+", "label_x": 4305.0, "node_type": "metabolite", "y": 1380.0, "x": 4285.0, "bigg_id": "h_c", "label_y": 1380.0}, "1576631": {"node_is_primary": false, "name": "Phosphate", "label_x": 4305.0, "node_type": "metabolite", "y": 1450.0, "x": 4285.0, "bigg_id": "pi_c", "label_y": 1450.0}, "1576630": {"node_is_primary": false, "name": "H2O", "label_x": 4295.0, "node_type": "metabolite", "y": 1140.0, "x": 4275.0, "bigg_id": "h2o_c", "label_y": 1140.0}, "1576637": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide - reduced", "label_x": 2710.0, "node_type": "metabolite", "y": 3585.0, "x": 2680.0, "bigg_id": "nadh_c", "label_y": 3590.0}, "1576636": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide", "label_x": 2690.0, "node_type": "metabolite", "y": 3310.0, "x": 2670.0, "bigg_id": "nad_c", "label_y": 3320.0}, "1576635": {"node_is_primary": false, "name": "H+", "label_x": 935.0, "node_type": "metabolite", "y": 4095.0, "x": 955.0, "bigg_id": "h_c", "label_y": 4095.0}, "1576634": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide - reduced", "label_x": 935.0, "node_type": "metabolite", "y": 4045.0, "x": 955.0, "bigg_id": "nadh_c", "label_y": 4045.0}, "1577043": {"y": 4071.0, "x": 2342.0, "node_type": "multimarker"}, "1577042": {"y": 4086.0, "x": 2356.0, "node_type": "midmarker"}, "1577041": {"y": 4100.0, "x": 2371.0, "node_type": "multimarker"}, "1577047": {"y": 4432.0, "x": 1460.0, "node_type": "midmarker"}, "1577046": {"y": 4470.0, "x": 1360.0, "node_type": "multimarker"}, "1577045": {"y": 4600.0, "x": 1360.0, "node_type": "midmarker"}, "1577044": {"y": 4730.0, "x": 1360.0, "node_type": "multimarker"}, "1577049": {"y": 2600.0, "x": 3110.0, "node_type": "midmarker"}, "1577048": {"y": 2600.0, "x": 3080.0, "node_type": "multimarker"}, "1576941": {"y": 3330.0, "x": 2310.0, "node_type": "multimarker"}, "1576940": {"y": 4158.0, "x": 4455.0, "node_type": "multimarker"}, "1576943": {"y": 3390.0, "x": 2190.0, "node_type": "multimarker"}, "1576942": {"y": 3360.0, "x": 2250.0, "node_type": "midmarker"}, "1576945": {"y": 1265.0, "x": 1307.0, "node_type": "midmarker"}, "1576944": {"y": 1265.0, "x": 1327.0, "node_type": "multimarker"}, "1576947": {"y": 4935.0, "x": 1715.0, "node_type": "midmarker"}, "1576946": {"y": 1265.0, "x": 1287.0, "node_type": "multimarker"}, "1576949": {"y": 3815.0, "x": 4247.0, "node_type": "multimarker"}, "1576628": {"node_is_primary": false, "name": "H2O", "label_x": 4175.82763671875, "node_type": "metabolite", "y": 3940.0, "x": 4201.0, "bigg_id": "h2o_c", "label_y": 3972.89208984375}, "1576629": {"node_is_primary": false, "name": "Ammonium", "label_x": 4160.99267578125, "node_type": "metabolite", "y": 3762.0, "x": 4193.0, "bigg_id": "nh4_c", "label_y": 3793.22314453125}, "1576888": {"y": 3020.0, "x": 3631.0, "node_type": "midmarker"}, "1576889": {"y": 2976.0, "x": 3588.0, "node_type": "multimarker"}, "1576983": {"y": 4255.0, "x": 1715.0, "node_type": "multimarker"}, "1576620": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide", "label_x": 2380.0, "node_type": "metabolite", "y": 3220.0, "x": 2360.0, "bigg_id": "nad_c", "label_y": 3220.0}, "1576621": {"node_is_primary": false, "name": "CO2", "label_x": 1979.703125, "node_type": "metabolite", "y": 3420.0, "x": 2060.0, "bigg_id": "co2_c", "label_y": 3415.23974609375}, "1576839": {"y": 1265.0, "x": 1977.0, "node_type": "multimarker"}, "1576838": {"y": 1265.0, "x": 1937.0, "node_type": "multimarker"}, "1576831": {"node_is_primary": false, "name": "H+", "label_x": 2460.1826171875, "node_type": "metabolite", "y": 700.0, "x": 2510.0, "bigg_id": "h_e", "label_y": 722.5455932617188}, "1576830": {"node_is_primary": false, "name": "Ubiquinol-8", "label_x": 3041.5869140625, "node_type": "metabolite", "y": 2740.0, "x": 3020.0, "bigg_id": "q8h2_c", "label_y": 2740.0}, "1576833": {"node_is_primary": false, "name": "H+", "label_x": 1228.8927001953125, "node_type": "metabolite", "y": 4770.0, "x": 1270.0, "bigg_id": "h_e", "label_y": 4750.95849609375}, "1576832": {"node_is_primary": false, "name": "H+", "label_x": 1950.0, "node_type": "metabolite", "y": 3860.0, "x": 1950.0, "bigg_id": "h_c", "label_y": 3840.0}, "1576835": {"y": 2775.0, "x": 1055.0, "node_type": "multimarker"}, "1576834": {"y": 2665.0, "x": 1055.0, "node_type": "multimarker"}, "1576837": {"y": 1265.0, "x": 1957.0, "node_type": "midmarker"}, "1576836": {"y": 2725.0, "x": 1055.0, "node_type": "midmarker"}, "1576688": {"node_is_primary": false, "name": "H+", "label_x": 351.3470764160156, "node_type": "metabolite", "y": 4045.0, "x": 345.0, "bigg_id": "h_e", "label_y": 4072.933837890625}, "1576689": {"node_is_primary": false, "name": "H+", "label_x": 675.0, "node_type": "metabolite", "y": 4045.0, "x": 675.0, "bigg_id": "h_c", "label_y": 4077.694091796875}, "1576567": {"node_is_primary": false, "name": "Coenzyme A", "label_x": 3448.892578125, "node_type": "metabolite", "y": 2960.0, "x": 3460.0, "bigg_id": "coa_c", "label_y": 2991.107421875}, "1576682": {"node_is_primary": false, "name": "H+", "label_x": 4398.884765625, "node_type": "metabolite", "y": 1150.0, "x": 4415.0, "bigg_id": "h_c", "label_y": 1187.7266845703125}, "1576683": {"node_is_primary": false, "name": "H2O", "label_x": 4482.7265625, "node_type": "metabolite", "y": 1030.0, "x": 4482.7265625, "bigg_id": "h2o_c", "label_y": 1010.0}, "1576680": {"node_is_primary": false, "name": "H+", "label_x": 4865.0, "node_type": "metabolite", "y": 1150.0, "x": 4865.0, "bigg_id": "h_e", "label_y": 1180.0}, "1576568": {"node_is_primary": false, "name": "ATP", "label_x": 3496.826416015625, "node_type": "metabolite", "y": 3030.0, "x": 3500.0, "bigg_id": "atp_c", "label_y": 3062.694091796875}, "1576686": {"node_is_primary": false, "name": "Coenzyme A", "label_x": 2786.826416015625, "node_type": "metabolite", "y": 4091.0, "x": 2806.0, "bigg_id": "coa_c", "label_y": 4132.21484375}, "1576687": {"node_is_primary": false, "name": "H+", "label_x": 2899.041015625, "node_type": "metabolite", "y": 4117.0, "x": 2897.0, "bigg_id": "h_c", "label_y": 4155.8671875}, "1576684": {"node_is_primary": false, "name": "H2O", "label_x": 2599.520751953125, "node_type": "metabolite", "y": 3860.0, "x": 2610.0, "bigg_id": "h2o_c", "label_y": 3890.1484375}, "1576685": {"node_is_primary": true, "name": "Citrate", "label_x": 2972.653076171875, "node_type": "metabolite", "y": 3986.0, "x": 2971.0, "bigg_id": "cit_c", "label_y": 3943.1826171875}, "1576664": {"node_is_primary": false, "name": "H+", "label_x": 4818.7197265625, "node_type": "metabolite", "y": 2921.942138671875, "x": 4791.7197265625, "bigg_id": "h_e", "label_y": 2921.942138671875}, "1576665": {"node_is_primary": false, "name": "H+", "label_x": 4389.423828125, "node_type": "metabolite", "y": 2763.553955078125, "x": 4461.380859375, "bigg_id": "h_c", "label_y": 2763.9423828125}, "1576666": {"node_is_primary": true, "name": "Formate", "label_x": 1500.0, "node_type": "metabolite", "y": 4843.322265625, "x": 1460.0, "bigg_id": "for_e", "label_y": 4843.322265625}, "1576667": {"node_is_primary": false, "name": "H2O", "label_x": 1587.0, "node_type": "metabolite", "y": 1160.0, "x": 1587.0, "bigg_id": "h2o_c", "label_y": 1140.0}, "1576660": {"node_is_primary": false, "name": "H+", "label_x": 1835.0, "node_type": "metabolite", "y": 4775.0, "x": 1815.0, "bigg_id": "h_e", "label_y": 4775.0}, "1576661": {"node_is_primary": false, "name": "H+", "label_x": 1839.76025390625, "node_type": "metabolite", "y": 4452.45458984375, "x": 1819.76025390625, "bigg_id": "h_c", "label_y": 4452.45458984375}, "1576662": {"node_is_primary": false, "name": "Phosphoenolpyruvate", "label_x": 877.8765258789062, "node_type": "metabolite", "y": 974.4060668945312, "x": 957.694091796875, "bigg_id": "pep_c", "label_y": 976.9517211914062}, "1576663": {"node_is_primary": false, "name": "Pyruvate", "label_x": 1193.082275390625, "node_type": "metabolite", "y": 972.8192138671875, "x": 1161.3470458984375, "bigg_id": "pyr_c", "label_y": 986.47216796875}, "1576668": {"node_is_primary": false, "name": "H+", "label_x": 1687.0, "node_type": "metabolite", "y": 1160.0, "x": 1687.0, "bigg_id": "h_c", "label_y": 1140.0}, "1576669": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide", "label_x": 1165.0, "node_type": "metabolite", "y": 2265.0, "x": 1145.0, "bigg_id": "nad_c", "label_y": 2265.0}, "1576905": {"y": 1270.0, "x": 3470.0, "node_type": "multimarker"}, "1576907": {"y": 1270.0, "x": 3520.0, "node_type": "midmarker"}, "1576906": {"y": 1270.0, "x": 3570.0, "node_type": "multimarker"}, "1576901": {"y": 3849.0, "x": 4364.0, "node_type": "multimarker"}, "1576900": {"y": 3869.0, "x": 4364.0, "node_type": "midmarker"}, "1576909": {"y": 3402.0, "x": 3783.0, "node_type": "midmarker"}, "1576908": {"y": 3480.0, "x": 3780.0, "node_type": "multimarker"}, "1577018": {"y": 1150.0, "x": 4625.0, "node_type": "multimarker"}, "1577019": {"y": 1150.0, "x": 4665.0, "node_type": "midmarker"}, "1577014": {"y": 3632.0, "x": 4078.0, "node_type": "multimarker"}, "1577015": {"y": 3632.0, "x": 4098.0, "node_type": "midmarker"}, "1577016": {"y": 3632.0, "x": 4118.0, "node_type": "multimarker"}, "1577017": {"y": 1150.0, "x": 4705.0, "node_type": "multimarker"}, "1577011": {"y": 3027.0, "x": 4666.0, "node_type": "midmarker"}, "1577012": {"y": 3027.0, "x": 4536.0, "node_type": "multimarker"}, "1577013": {"y": 3027.0, "x": 4796.0, "node_type": "multimarker"}, "1576840": {"y": 1660.0, "x": 4660.0, "node_type": "midmarker"}, "1576489": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide phosphate", "label_x": 1907.0, "node_type": "metabolite", "y": 1165.0, "x": 1907.0, "bigg_id": "nadp_c", "label_y": 1145.0}, "1576539": {"node_is_primary": true, "name": "Ubiquinone-8", "label_x": 4686.61181640625, "node_type": "metabolite", "y": 2215.0361328125, "x": 4758.67626953125, "bigg_id": "q8_c", "label_y": 2192.47509765625}, "1576534": {"node_is_primary": true, "name": "ATP", "label_x": 4215.0, "node_type": "metabolite", "y": 1040.0, "x": 4215.0, "bigg_id": "atp_c", "label_y": 1010.0}, "1576535": {"node_is_primary": true, "name": "AMP", "label_x": 4033.388427734375, "node_type": "metabolite", "y": 1070.0, "x": 4065.0, "bigg_id": "amp_c", "label_y": 1030.661865234375}, "1576536": {"node_is_primary": true, "name": "ADP", "label_x": 4196.611328125, "node_type": "metabolite", "y": 1510.0, "x": 4215.0, "bigg_id": "adp_c", "label_y": 1556.1151123046875}, "1576537": {"node_is_primary": true, "name": "L-Glutamine", "label_x": 4851.38134765625, "node_type": "metabolite", "y": 4158.0, "x": 4882.0, "bigg_id": "gln__L_e", "label_y": 4199.2802734375}, "1576530": {"node_is_primary": false, "name": "Phosphate", "label_x": 686.744140625, "node_type": "metabolite", "y": 1565.0, "x": 755.0, "bigg_id": "pi_c", "label_y": 1563.4132080078125}, "1576531": {"node_is_primary": true, "name": "Succinate", "label_x": 4950.4462890625, "node_type": "metabolite", "y": 2880.0, "x": 4932.0, "bigg_id": "succ_e", "label_y": 2915.280517578125}, "1576532": {"node_is_primary": true, "name": "Glyoxylate", "label_x": 3211.3271484375, "node_type": "metabolite", "y": 3570.0, "x": 3180.0, "bigg_id": "glx_c", "label_y": 3543.267578125}, "1576533": {"node_is_primary": true, "name": "Succinate", "label_x": 3439.01611328125, "node_type": "metabolite", "y": 2867.0, "x": 3420.0, "bigg_id": "succ_c", "label_y": 2838.810302734375}, "1576879": {"y": 3635.0, "x": 4541.0, "node_type": "multimarker"}, "1576878": {"y": 3635.0, "x": 4645.0, "node_type": "midmarker"}, "1576875": {"y": 3655.0, "x": 1055.0, "node_type": "multimarker"}, "1576874": {"y": 2035.0, "x": 2178.0, "node_type": "multimarker"}, "1576877": {"y": 3745.0, "x": 1055.0, "node_type": "multimarker"}, "1576876": {"y": 3705.0, "x": 1055.0, "node_type": "midmarker"}, "1576871": {"y": 4914.0, "x": 3621.0, "node_type": "midmarker"}, "1576569": {"node_is_primary": false, "name": "Phosphate", "label_x": 3814.0, "node_type": "metabolite", "y": 3051.0, "x": 3794.0, "bigg_id": "pi_c", "label_y": 3051.0}, "1576873": {"y": 1955.0, "x": 2175.0, "node_type": "multimarker"}, "1576872": {"y": 1995.0, "x": 2178.0, "node_type": "midmarker"}, "1576681": {"node_is_primary": false, "name": "Phosphate", "label_x": 4459.546875, "node_type": "metabolite", "y": 1330.0, "x": 4495.0, "bigg_id": "pi_c", "label_y": 1293.5970458984375}, "1576581": {"node_is_primary": false, "name": "Phosphate", "label_x": 4454.0, "node_type": "metabolite", "y": 4054.0, "x": 4434.0, "bigg_id": "pi_c", "label_y": 4054.0}, "1576580": {"node_is_primary": false, "name": "H+", "label_x": 4454.0, "node_type": "metabolite", "y": 4004.0, "x": 4434.0, "bigg_id": "h_c", "label_y": 4004.0}, "1576585": {"node_is_primary": false, "name": "Coenzyme A", "label_x": 3628.99267578125, "node_type": "metabolite", "y": 3506.0, "x": 3684.0, "bigg_id": "coa_c", "label_y": 3483.05029296875}, "1576584": {"node_is_primary": true, "name": "D-Lactate", "label_x": 1089.0, "node_type": "metabolite", "y": 4345.0, "x": 1055.0, "bigg_id": "lac__D_c", "label_y": 4349.0}, "1576587": {"node_is_primary": false, "name": "CO2", "label_x": 3898.0, "node_type": "metabolite", "y": 3285.0, "x": 3872.0, "bigg_id": "co2_c", "label_y": 3285.0}, "1576586": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide", "label_x": 3606.208740234375, "node_type": "metabolite", "y": 3558.0, "x": 3684.0, "bigg_id": "nad_c", "label_y": 3539.885009765625}, "1576589": {"node_is_primary": false, "name": "Coenzyme A", "label_x": 1165.0, "node_type": "metabolite", "y": 4045.0, "x": 1165.0, "bigg_id": "coa_c", "label_y": 4065.0}, "1576588": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide - reduced", "label_x": 3846.0, "node_type": "metabolite", "y": 3233.0, "x": 3820.0, "bigg_id": "nadh_c", "label_y": 3233.0}, "1576622": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide - reduced", "label_x": 1994.9427490234375, "node_type": "metabolite", "y": 3370.0, "x": 2080.0, "bigg_id": "nadh_c", "label_y": 3350.958740234375}, "1576623": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide phosphate", "label_x": 1257.0, "node_type": "metabolite", "y": 1160.0, "x": 1257.0, "bigg_id": "nadp_c", "label_y": 1140.0}, "1576624": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide phosphate - reduced", "label_x": 1430.0, "node_type": "metabolite", "y": 1160.0, "x": 1407.0, "bigg_id": "nadph_c", "label_y": 1140.0}, "1576625": {"node_is_primary": false, "name": "H+", "label_x": 1357.0, "node_type": "metabolite", "y": 1160.0, "x": 1357.0, "bigg_id": "h_c", "label_y": 1140.0}, "1576626": {"node_is_primary": true, "name": "6-phospho-D-glucono-1,5-lactone", "label_x": 1507.0, "node_type": "metabolite", "y": 1265.0, "x": 1507.0, "bigg_id": "6pgl_c", "label_y": 1235.0}, "1576627": {"node_is_primary": true, "name": "Acetate", "label_x": 1759.0985107421875, "node_type": "metabolite", "y": 4845.0, "x": 1715.0, "bigg_id": "ac_e", "label_y": 4848.173828125}, "1577050": {"y": 2600.0, "x": 3140.0, "node_type": "multimarker"}, "1577051": {"y": 1361.5867919921875, "x": 576.050048828125, "node_type": "multimarker"}, "1577052": {"y": 1361.586669921875, "x": 640.0, "node_type": "midmarker"}, "1577053": {"y": 1361.586669921875, "x": 704.5778198242188, "node_type": "multimarker"}, "1577054": {"y": 1360.0, "x": 182.0, "node_type": "midmarker"}, "1577056": {"y": 736.0, "x": 2610.0, "node_type": "multimarker"}, "1577057": {"y": 756.0, "x": 2610.0, "node_type": "midmarker"}, "1577058": {"y": 980.0, "x": 2610.0, "node_type": "multimarker"}, "1577059": {"y": 470.0, "x": 2610.0, "node_type": "midmarker"}, "1576897": {"y": 1735.0, "x": 1695.0, "node_type": "multimarker"}, "1576896": {"y": 1735.0, "x": 1525.0, "node_type": "midmarker"}, "1576895": {"y": 3636.0, "x": 5015.0, "node_type": "midmarker"}, "1576893": {"y": 1690.0, "x": 1055.0, "node_type": "multimarker"}, "1576892": {"y": 1775.0, "x": 1055.0, "node_type": "multimarker"}, "1576891": {"y": 1735.0, "x": 1055.0, "node_type": "midmarker"}, "1576890": {"y": 3063.0, "x": 3666.0, "node_type": "multimarker"}, "1576956": {"y": 4225.0, "x": 1055.0, "node_type": "multimarker"}, "1576957": {"y": 4175.0, "x": 1055.0, "node_type": "midmarker"}, "1576954": {"y": 1350.0, "x": 4215.0, "node_type": "multimarker"}, "1576955": {"y": 4125.0, "x": 1055.0, "node_type": "multimarker"}, "1576952": {"y": 1200.0, "x": 4215.0, "node_type": "multimarker"}, "1576953": {"y": 1260.0, "x": 4215.0, "node_type": "midmarker"}, "1576899": {"y": 3889.0, "x": 4364.0, "node_type": "multimarker"}, "1576898": {"y": 1735.0, "x": 1405.0, "node_type": "multimarker"}, "1576958": {"y": 3456.0, "x": 2578.0, "node_type": "multimarker"}, "1576959": {"y": 3404.0, "x": 2577.0, "node_type": "midmarker"}, "1576950": {"y": 3877.0, "x": 4247.0, "node_type": "multimarker"}, "1576951": {"y": 3857.0, "x": 4247.0, "node_type": "midmarker"}, "1576826": {"node_is_primary": true, "name": "D-Fructose", "label_x": 284.1323547363281, "node_type": "metabolite", "y": 1360.0, "x": 300.0, "bigg_id": "fru_e", "label_y": 1405.8675537109375}, "1576827": {"node_is_primary": true, "name": "Nicotinamide adenine dinucleotide - reduced", "label_x": 4322.0859375, "node_type": "metabolite", "y": 2478.91357421875, "x": 4417.8271484375, "bigg_id": "nadh_c", "label_y": 2462.79833984375}, "1576824": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide - reduced", "label_x": 2347.0, "node_type": "metabolite", "y": 3935.0, "x": 2333.0, "bigg_id": "nadh_c", "label_y": 3921.0}, "1576825": {"node_is_primary": false, "name": "Coenzyme A", "label_x": 2140.0, "node_type": "metabolite", "y": 3860.0, "x": 2130.0, "bigg_id": "coa_c", "label_y": 3840.0}, "1576822": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide", "label_x": 2496.0, "node_type": "metabolite", "y": 4065.0, "x": 2482.0, "bigg_id": "nad_c", "label_y": 4051.0}, "1576988": {"y": 3868.0, "x": 4116.0, "node_type": "midmarker"}, "1576820": {"node_is_primary": false, "name": "H+", "label_x": 4273.546875, "node_type": "metabolite", "y": 2570.0, "x": 4310.0, "bigg_id": "h_c", "label_y": 2604.6689453125}, "1576821": {"node_is_primary": false, "name": "Pyruvate", "label_x": 692.5455932617188, "node_type": "metabolite", "y": 1237.785400390625, "x": 714.76025390625, "bigg_id": "pyr_c", "label_y": 1207.785400390625}, "1576985": {"y": 4918.0, "x": 3991.0, "node_type": "midmarker"}, "1576987": {"y": 3848.0, "x": 4116.0, "node_type": "multimarker"}, "1576986": {"y": 3888.0, "x": 4116.0, "node_type": "multimarker"}, "1576981": {"y": 4305.0, "x": 1715.0, "node_type": "multimarker"}, "1576980": {"y": 4937.93359375, "x": 2500.0, "node_type": "midmarker"}, "1576828": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide", "label_x": 2070.0, "node_type": "metabolite", "y": 3860.0, "x": 2070.0, "bigg_id": "nad_c", "label_y": 3840.0}, "1576829": {"node_is_primary": true, "name": "Ethanol", "label_x": 2522.0, "node_type": "metabolite", "y": 4228.0, "x": 2501.0, "bigg_id": "etoh_c", "label_y": 4206.0}, "1576570": {"node_is_primary": true, "name": "Succinyl-CoA", "label_x": 3772.230712890625, "node_type": "metabolite", "y": 3193.0, "x": 3739.0, "bigg_id": "succoa_c", "label_y": 3193.479248046875}, "1576571": {"node_is_primary": false, "name": "ADP", "label_x": 3788.0, "node_type": "metabolite", "y": 3116.0, "x": 3768.0, "bigg_id": "adp_c", "label_y": 3126.0}, "1576572": {"node_is_primary": false, "name": "ATP", "label_x": 1165.0, "node_type": "metabolite", "y": 1645.0, "x": 1145.0, "bigg_id": "atp_c", "label_y": 1645.0}, "1576573": {"node_is_primary": false, "name": "ADP", "label_x": 1165.0, "node_type": "metabolite", "y": 1805.0, "x": 1145.0, "bigg_id": "adp_c", "label_y": 1805.0}, "1576574": {"node_is_primary": false, "name": "H+", "label_x": 1165.0, "node_type": "metabolite", "y": 1855.0, "x": 1145.0, "bigg_id": "h_c", "label_y": 1855.0}, "1576575": {"node_is_primary": true, "name": "Glyceraldehyde 3-phosphate", "label_x": 1085.0, "node_type": "metabolite", "y": 2195.0, "x": 1055.0, "bigg_id": "g3p_c", "label_y": 2195.0}, "1576576": {"node_is_primary": false, "name": "ATP", "label_x": 4474.0, "node_type": "metabolite", "y": 3755.0, "x": 4440.0, "bigg_id": "atp_c", "label_y": 3753.0}, "1576577": {"node_is_primary": false, "name": "Ammonium", "label_x": 4477.0, "node_type": "metabolite", "y": 3805.0, "x": 4440.0, "bigg_id": "nh4_c", "label_y": 3811.0}, "1576578": {"node_is_primary": true, "name": "L-Glutamine", "label_x": 4245.0, "node_type": "metabolite", "y": 4094.0, "x": 4246.0, "bigg_id": "gln__L_c", "label_y": 4130.0}, "1576579": {"node_is_primary": false, "name": "ADP", "label_x": 4454.0, "node_type": "metabolite", "y": 3954.0, "x": 4434.0, "bigg_id": "adp_c", "label_y": 3954.0}, "1576928": {"y": 1900.0, "x": 4660.0, "node_type": "midmarker"}, "1576651": {"node_is_primary": false, "name": "ATP", "label_x": 1835.0, "node_type": "metabolite", "y": 4335.0, "x": 1815.0, "bigg_id": "atp_c", "label_y": 4335.0}, "1576650": {"node_is_primary": false, "name": "H+", "label_x": 2620.0, "node_type": "metabolite", "y": 4400.0, "x": 2600.0, "bigg_id": "h_c", "label_y": 4400.0}, "1576653": {"node_is_primary": false, "name": "ADP", "label_x": 1835.0, "node_type": "metabolite", "y": 4225.0, "x": 1815.0, "bigg_id": "adp_c", "label_y": 4225.0}, "1576652": {"node_is_primary": true, "name": "Acetate", "label_x": 1745.0, "node_type": "metabolite", "y": 4385.0, "x": 1715.0, "bigg_id": "ac_c", "label_y": 4385.0}, "1576655": {"node_is_primary": false, "name": "H+", "label_x": 4002.0, "node_type": "metabolite", "y": 3982.0, "x": 4029.0, "bigg_id": "h_c", "label_y": 3986.0}, "1576654": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide phosphate - reduced", "label_x": 3993.9423828125, "node_type": "metabolite", "y": 3932.0, "x": 4029.0, "bigg_id": "nadph_c", "label_y": 3909.05029296875}, "1576657": {"node_is_primary": true, "name": "Fumarate", "label_x": 2879.817626953125, "node_type": "metabolite", "y": 650.0, "x": 2840.0, "bigg_id": "fum_e", "label_y": 635.0911865234375}, "1576656": {"node_is_primary": false, "name": "Nicotinamide adenine dinucleotide phosphate", "label_x": 3957.985595703125, "node_type": "metabolite", "y": 3759.0, "x": 4043.0, "bigg_id": "nadp_c", "label_y": 3736.215576171875}, "1576659": {"node_is_primary": false, "name": "H+", "label_x": 2954.28076171875, "node_type": "metabolite", "y": 1010.0, "x": 2940.0, "bigg_id": "h_c", "label_y": 1038.4132080078125}, "1576658": {"node_is_primary": false, "name": "H+", "label_x": 2962.214599609375, "node_type": "metabolite", "y": 700.0, "x": 2940.0, "bigg_id": "h_e", "label_y": 718.4132080078125}, "1576912": {"y": 3995.0, "x": 1255.0, "node_type": "multimarker"}, "1576913": {"y": 3995.0, "x": 1415.0, "node_type": "multimarker"}, "1576910": {"y": 3330.0, "x": 3776.0, "node_type": "multimarker"}, "1576911": {"y": 3995.0, "x": 1335.0, "node_type": "midmarker"}, "1576916": {"y": 3526.0, "x": 1404.0, "node_type": "midmarker"}, "1576917": {"y": 3554.0, "x": 1485.0, "node_type": "multimarker"}, "1576914": {"y": 1660.0, "x": 4970.0, "node_type": "midmarker"}, "1576918": {"y": 3503.0, "x": 1335.0, "node_type": "multimarker"}, "1576919": {"y": 4520.0, "x": 2880.0, "node_type": "multimarker"}, "1577028": {"y": 3360.0, "x": 2310.0, "node_type": "multimarker"}, "1577021": {"y": 3918.0, "x": 2840.0, "node_type": "multimarker"}, "1577020": {"y": 3837.0, "x": 2744.0, "node_type": "multimarker"}, "1577023": {"y": 3945.0, "x": 375.0, "node_type": "multimarker"}, "1577022": {"y": 3886.0, "x": 2798.0, "node_type": "midmarker"}, "1577025": {"y": 3945.0, "x": 505.0, "node_type": "midmarker"}, "1577024": {"y": 3945.0, "x": 645.0, "node_type": "multimarker"}, "1577027": {"y": 3410.0, "x": 2220.0, "node_type": "multimarker"}, "1577026": {"y": 3390.0, "x": 2260.0, "node_type": "midmarker"}, "1576967": {"y": 4604.0, "x": 3621.0, "node_type": "midmarker"}, "1576966": {"y": 1735.0, "x": 2175.0, "node_type": "multimarker"}, "1576965": {"y": 1695.0, "x": 2175.0, "node_type": "midmarker"}, "1576964": {"y": 1645.0, "x": 2175.0, "node_type": "multimarker"}, "1576962": {"y": 4924.0, "x": 3257.0, "node_type": "midmarker"}, "1576961": {"y": 4614.0, "x": 3257.0, "node_type": "midmarker"}, "1576960": {"y": 3341.0, "x": 2582.0, "node_type": "multimarker"}, "1576969": {"y": 3228.0, "x": 5032.0, "node_type": "midmarker"}, "1576499": {"node_is_primary": false, "name": "H+", "label_x": 3522.892333984375, "node_type": "metabolite", "y": 1080.287841796875, "x": 3510.0, "bigg_id": "h_c", "label_y": 1099.0072021484375}, "1576999": {"y": 1041.710205078125, "x": 1056.5867919921875, "node_type": "multimarker"}}, "canvas": {"y": 314.36893920898433, "x": 7.857062530517567, "height": 4860.457037353515, "width": 5894.515691375733}, "text_labels": {}}]